LCE3A and OIT3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		LCE3A	OIT3
Description		late cornified envelope 3A	oncoprotein induced transcript 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component		Extracellular Space Nucleus Nuclear Envelope Cell Surface
	Molecular Function	Protein Binding	Calcium Ion Binding Protein Binding
	Biological Process	Epidermis Development Keratinization Killing Of Cells Of Another Organism Defense Response To Gram-negative Bacterium Defense Response To Gram-positive Bacterium	Renal System Process
Pathways		Formation of the cornified envelope
Drugs
Diseases
GWAS		Allergic disease (asthma, hay fever or eczema) ( 29785011) Asthma ( 31619474) Asthma or allergic disease (pleiotropy) ( 29785011) Atopic dermatitis ( 23727859) Inflammatory skin disease ( 25574825) Psoriasis ( 19169255) Psoriasis vulgaris ( 26626624)	Coronary artery disease ( 33020668) Low density lipoprotein cholesterol levels ( 29403010 33339817) Refractive error ( 32231278) Total cholesterol levels ( 29403010 33339817)
Interacting Genes		74 interacting genes: ADAMTSL4 ALPP CHIC2 CRCT1 CYSRT1 EFEMP1 EFEMP2 FBLN1 HOXA1 KPRP KRTAP1-1 KRTAP1-3 KRTAP1-5 KRTAP10-1 KRTAP10-11 KRTAP10-5 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP11-1 KRTAP12-1 KRTAP12-3 KRTAP12-4 KRTAP17-1 KRTAP2-3 KRTAP2-4 KRTAP3-1 KRTAP3-2 KRTAP3-3 KRTAP4-1 KRTAP4-11 KRTAP4-12 KRTAP4-2 KRTAP4-4 KRTAP4-5 KRTAP5-11 KRTAP5-2 KRTAP5-3 KRTAP5-4 KRTAP5-6 KRTAP5-7 KRTAP5-8 KRTAP5-9 KRTAP6-3 KRTAP9-2 KRTAP9-3 KRTAP9-8 LCE1C LCE2A LCE2B LCE2C LCE2D LCE3B LCE4A MACO1 MDFI NBPF19 NOTCH2NLA OIT3 PCSK5 PLA2G10 PLSCR2 RGS17 RGS20 SMCP SPRY1 SPRY3 TGFB1 TGM1 TRIM42 TSPAN4 VASN VWC2 VWC2L	9 interacting genes: CRCT1 FBXO34 HOXA1 KRTAP11-1 LCE1C LCE1F LCE3A MEOX2 VAC14
Entrez ID		353142	170392
HPRD ID		13973	17660
Ensembl ID		ENSG00000185962	ENSG00000138315
Uniprot IDs		Q5TA76	Q8WWZ8
PDB IDs
Enriched GO Terms of Interacting Partners?		Intermediate Filament Keratin Filament Keratinization Epidermis Development Hair Cycle Protein Binding Cytosol Tissue Development Elastic Fiber Identical Protein Binding Interstitial Matrix	Keratinization Epidermis Development
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