LCE2A and RGS17

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		LCE2A	RGS17
Gene Name		late cornified envelope 2A	regulator of G-protein signaling 17
Image		No pdb structure
Gene Ontology Annotations	Cellular Component		Nucleus Cytoplasm Plasma Membrane
	Molecular Function		GTPase Activator Activity
	Biological Process	Keratinization	Termination Of G-protein Coupled Receptor Signaling Pathway Positive Regulation Of GTPase Activity
Pathways			Signaling by GPCR GPCR downstream signaling G alpha (z) signalling events
Drugs
Diseases
GWAS			Prostate cancer ( 23535732)
Protein-Protein Interactions		14 interactors: KRTAP10-3 KRTAP10-5 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP3-2 KRTAP4-2 KRTAP5-9 KRTAP9-2 MEOX2 OTX1 RGS17 RGS20 SUMO1P1	18 interactors: ADRB2 AQP1 DHX37 GNAI1 GNAI3 HOXA1 LCE2A LCE3C LCE4A NUFIP2 OSTM1 OTX1 PTGER3 RABEP1 RBBP8 RPL10A SMCP TBC1D16
Entrez ID		353139	26575
HPRD ID		13971	06223
Ensembl ID		ENSG00000187173	ENSG00000091844
Uniprot IDs		Q5TA79	Q9UGC6
PDB IDs			1ZV4
Enriched GO Terms of Interacting Partners?		Termination Of G-protein Coupled Receptor Signaling Pathway Termination Of Signal Transduction Negative Regulation Of G-protein Coupled Receptor Protein Signaling Pathway Regulation Of G-protein Coupled Receptor Protein Signaling Pathway Anterior/posterior Pattern Specification Somite Specification Diencephalon Morphogenesis Positive Regulation Of Metabolic Process Segment Specification Pattern Specification Process Forebrain Morphogenesis	Adenylate Cyclase-modulating G-protein Coupled Receptor Signaling Pathway G-protein Coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger Keratinization Heat Generation Keratinocyte Differentiation Membrane Fusion Epidermal Cell Differentiation Temperature Homeostasis Bicarbonate Transport Vesicle Organization Skin Development Regulation Of Body Fluid Levels Vesicle Fusion Regulation Of Adenylate Cyclase Activity Metanephric Descending Thin Limb Development Metanephric Proximal Straight Tubule Development Metanephric Proximal Convoluted Tubule Segment 2 Development Abducens Nerve Formation Maintenance Of Symbiont-containing Vacuole By Host Transepithelial Water Transport Optokinetic Behavior Epidermis Development Adenylate Cyclase-inhibiting G-protein Coupled Receptor Signaling Pathway Regulation Of Cyclase Activity Cellular Response To Retinoic Acid Organelle Fusion Facial Nucleus Development Carbon Dioxide Transmembrane Transport Corticotropin Secretion Desensitization Of G-protein Coupled Receptor Protein Signaling Pathway By Arrestin Establishment Or Maintenance Of Actin Cytoskeleton Polarity Developmental Process Regulation Of CAMP Biosynthetic Process DNA Double-strand Break Processing Involved In Repair Via Single-strand Annealing Metanephric Proximal Convoluted Tubule Development Rhombomere 4 Development Nitric Oxide Transport Semicircular Canal Formation Cellular Response To Mercury Ion Vasodilation By Norepinephrine-epinephrine Involved In Regulation Of Systemic Arterial Blood Pressure Renal System Process Regulation Of CAMP Metabolic Process Inner Ear Morphogenesis Membrane Organization Rhombomere 3 Development Rhombomere 5 Development Metanephric Proximal Tubule Development Fever Generation Organ Development Anatomical Structure Development
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