IFNA4 and ALDOA

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		IFNA4	ALDOA
Gene Name		interferon, alpha 4	aldolase A, fructose-bisphosphate
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Region Extracellular Space	Extracellular Region Extracellular Space Nucleus Cytosol Actin Cytoskeleton Membrane Platelet Alpha Granule Lumen M Band I Band Extracellular Vesicular Exosome
	Molecular Function	Cytokine Activity Type I Interferon Receptor Binding	Actin Binding Fructose-bisphosphate Aldolase Activity Protein Binding Cytoskeletal Protein Binding Tubulin Binding Identical Protein Binding Poly(A) RNA Binding Fructose Binding
	Biological Process	Adaptive Immune Response T Cell Activation Involved In Immune Response Natural Killer Cell Activation Involved In Immune Response Humoral Immune Response Blood Coagulation Response To Virus Cytokine-mediated Signaling Pathway B Cell Differentiation Positive Regulation Of Peptidyl-serine Phosphorylation Of STAT Protein B Cell Proliferation Response To Exogenous DsRNA Innate Immune Response Regulation Of MHC Class I Biosynthetic Process Defense Response To Virus Type I Interferon Signaling Pathway Regulation Of Type I Interferon-mediated Signaling Pathway	Platelet Degranulation Carbohydrate Metabolic Process Fructose Metabolic Process Glucose Metabolic Process Gluconeogenesis Glycolytic Process ATP Biosynthetic Process Striated Muscle Contraction Actin Filament Organization Blood Coagulation Regulation Of Cell Shape Pathogenesis Platelet Activation Fructose 1,6-bisphosphate Metabolic Process Small Molecule Metabolic Process Muscle Cell Cellular Homeostasis Protein Homotetramerization
Pathways		RIG-I/MDA5 mediated induction of IFN-alpha/beta pathways Regulation of IFNA signaling Interferon Signaling TRAF6 mediated IRF7 activation Cytokine Signaling in Immune system Interferon alpha/beta signaling Factors involved in megakaryocyte development and platelet production Innate Immune System	Gluconeogenesis Glucose metabolism Myoclonic epilepsy of Lafora Response to elevated platelet cytosolic Ca2+ Glycogen storage diseases Glycolysis Platelet degranulation Platelet activation, signaling and aggregation Metabolism of carbohydrates
Drugs			1,6-Fructose Diphosphate (Linear Form) 1,3-Dihydroxyacetonephosphate 1,6-DI-O-PHOSPHONO-D-MANNITOL N-(4-CHLOROPHENYL)-3-(PHOSPHONOOXY)NAPHTHALENE-2-CARBOXAMIDE
Diseases
GWAS
Protein-Protein Interactions		1 interactors: ALDOA	23 interactors: ADRB2 ALDOB ALDOC ATP6V1E1 BCAT2 CACNA1A DYNLL1 EGFR FANCA GALNT6 GPD2 IFNA4 MLH1 MYOC PCNA PIAS4 PLD2 SUMO4 TERF1 TGM2 TRIM63 TUBB XRN1
Entrez ID		3441	226
HPRD ID		00952	00070
Ensembl ID		ENSG00000236637	ENSG00000149925
Uniprot IDs		P05014	P04075
PDB IDs			1ALD 2ALD 4ALD
Enriched GO Terms of Interacting Partners?		Fructose 1,6-bisphosphate Metabolic Process Fructose Metabolic Process Muscle Cell Cellular Homeostasis ATP Biosynthetic Process Gluconeogenesis Hexose Biosynthetic Process Protein Homotetramerization Platelet Degranulation Purine Ribonucleoside Monophosphate Biosynthetic Process Striated Muscle Contraction Nucleoside Triphosphate Biosynthetic Process Glycolytic Process Ribonucleoside Monophosphate Biosynthetic Process Nucleoside Monophosphate Biosynthetic Process Protein Tetramerization Pyruvate Metabolic Process ATP Metabolic Process Glucose Metabolic Process Carbohydrate Catabolic Process Carbohydrate Biosynthetic Process Regulation Of Cell Shape Purine Nucleotide Biosynthetic Process Ribose Phosphate Biosynthetic Process Platelet Activation Pathogenesis Hexose Metabolic Process Muscle Contraction Purine Nucleoside Metabolic Process Monosaccharide Metabolic Process Protein Homooligomerization Muscle System Process Ribonucleotide Metabolic Process Nucleoside Metabolic Process Nucleotide Biosynthetic Process Actin Filament Organization Purine Nucleotide Metabolic Process Ribose Phosphate Metabolic Process Exocytosis Generation Of Precursor Metabolites And Energy Blood Coagulation Hemostasis Protein Oligomerization Regulation Of Cell Morphogenesis Secretion By Cell Monocarboxylic Acid Metabolic Process Nucleotide Metabolic Process Regulation Of Body Fluid Levels Wound Healing Actin Cytoskeleton Organization Secretion	Protein Complex Assembly Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Fructose 1,6-bisphosphate Metabolic Process Glucose Metabolic Process Gluconeogenesis Hexose Biosynthetic Process Cellular Component Assembly Skeletal Muscle Adaptation Hexose Metabolic Process Monosaccharide Metabolic Process Desensitization Of G-protein Coupled Receptor Protein Signaling Pathway Response To Stimulus Fructose Metabolic Process Catabolic Process Cell Cycle G2/M Transition Of Mitotic Cell Cycle Homeostatic Process Organ Development Regulation Of DNA Replication Cellular Protein Complex Assembly Protein Sumoylation Cell Cycle Process Carbohydrate Catabolic Process Mitotic Cell Cycle Process Cellular Response To Dexamethasone Stimulus Carbohydrate Biosynthetic Process Telomere Maintenance Via Telomere Lengthening Developmental Process Response To Dexamethasone Cellular Metabolic Process Mitotic Cell Cycle Response To Stress System Development Salivary Gland Morphogenesis Cellular Response To Stimulus Positive Regulation Of Intracellular Signal Transduction Regulation Of Vasodilation Salivary Gland Development Metal Ion Homeostasis Positive Regulation Of Signal Transduction Isoleucine Catabolic Process Alkanesulfonate Metabolic Process Cerebellar Molecular Layer Development Positive Regulation Of Deoxyribonuclease Activity Skeletal Muscle Hypertrophy Meiotic Metaphase I Plate Congression ERBB2-ERBB3 Signaling Pathway Meiotic Spindle Midzone Assembly Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay
Tagcloud ?			actb aldr catb catd catg co3 conceptus cst6 gd1b gda gdi2 gsn hsp7c hsp90a hsp90a1 hspa8 idhc ifnt itraq phosphorylase pnp pnph ret4 rpb4 serpina31 tera timp2 ulf vcn
Tagcloud (Difference) ?			actb aldr catb catd catg co3 conceptus cst6 gd1b gda gdi2 gsn hsp7c hsp90a hsp90a1 hspa8 idhc ifnt itraq phosphorylase pnp pnph ret4 rpb4 serpina31 tera timp2 ulf vcn
Tagcloud (Intersection) ?