ALDOA and BCAT2

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		ALDOA	BCAT2
Gene Name		aldolase A, fructose-bisphosphate	branched chain amino-acid transaminase 2, mitochondrial
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Gene Ontology Annotations	Cellular Component	Extracellular Region Extracellular Space Nucleus Cytosol Actin Cytoskeleton Membrane Platelet Alpha Granule Lumen M Band I Band Extracellular Vesicular Exosome	Mitochondrion Mitochondrial Matrix
	Molecular Function	Actin Binding Fructose-bisphosphate Aldolase Activity Protein Binding Cytoskeletal Protein Binding Tubulin Binding Identical Protein Binding Poly(A) RNA Binding Fructose Binding	Branched-chain-amino-acid Transaminase Activity L-leucine Transaminase Activity L-valine Transaminase Activity L-isoleucine Transaminase Activity
	Biological Process	Platelet Degranulation Carbohydrate Metabolic Process Fructose Metabolic Process Glucose Metabolic Process Gluconeogenesis Glycolytic Process ATP Biosynthetic Process Striated Muscle Contraction Actin Filament Organization Blood Coagulation Regulation Of Cell Shape Pathogenesis Platelet Activation Fructose 1,6-bisphosphate Metabolic Process Small Molecule Metabolic Process Muscle Cell Cellular Homeostasis Protein Homotetramerization	Isoleucine Catabolic Process Leucine Metabolic Process Valine Metabolic Process Branched-chain Amino Acid Biosynthetic Process Branched-chain Amino Acid Catabolic Process Regulation Of Hormone Levels Cellular Nitrogen Compound Metabolic Process Small Molecule Metabolic Process
Pathways		Gluconeogenesis Glucose metabolism Myoclonic epilepsy of Lafora Response to elevated platelet cytosolic Ca2+ Glycogen storage diseases Glycolysis Platelet degranulation Platelet activation, signaling and aggregation Metabolism of carbohydrates	Branched-chain amino acid catabolism Metabolism of amino acids and derivatives
Drugs		1,6-Fructose Diphosphate (Linear Form) 1,3-Dihydroxyacetonephosphate 1,6-DI-O-PHOSPHONO-D-MANNITOL N-(4-CHLOROPHENYL)-3-(PHOSPHONOOXY)NAPHTHALENE-2-CARBOXAMIDE	Pyridoxal Phosphate L-Glutamic Acid L-Leucine L-Isoleucine Pyridoxamine-5\'-Phosphate N-[O-Phosphono-Pyridoxyl]-Isoleucine Alpha-ketoisovalerate
Diseases
GWAS
Protein-Protein Interactions		23 interactors: ADRB2 ALDOB ALDOC ATP6V1E1 BCAT2 CACNA1A DYNLL1 EGFR FANCA GALNT6 GPD2 IFNA4 MLH1 MYOC PCNA PIAS4 PLD2 SUMO4 TERF1 TGM2 TRIM63 TUBB XRN1	4 interactors: ALDOA APP CREB3 PTGDS
Entrez ID		226	587
HPRD ID		00070	00217
Ensembl ID		ENSG00000149925	ENSG00000105552
Uniprot IDs		P04075	O15382
PDB IDs		1ALD 2ALD 4ALD	1EKF 1EKP 1EKV 1KT8 1KTA 2A1H 2HDK 2HG8 2HGW 2HGX 2HHF
Enriched GO Terms of Interacting Partners?		Protein Complex Assembly Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Fructose 1,6-bisphosphate Metabolic Process Glucose Metabolic Process Gluconeogenesis Hexose Biosynthetic Process Cellular Component Assembly Skeletal Muscle Adaptation Hexose Metabolic Process Monosaccharide Metabolic Process Desensitization Of G-protein Coupled Receptor Protein Signaling Pathway Response To Stimulus Fructose Metabolic Process Catabolic Process Cell Cycle G2/M Transition Of Mitotic Cell Cycle Homeostatic Process Organ Development Regulation Of DNA Replication Cellular Protein Complex Assembly Protein Sumoylation Cell Cycle Process Carbohydrate Catabolic Process Mitotic Cell Cycle Process Cellular Response To Dexamethasone Stimulus Carbohydrate Biosynthetic Process Telomere Maintenance Via Telomere Lengthening Developmental Process Response To Dexamethasone Cellular Metabolic Process Mitotic Cell Cycle Response To Stress System Development Salivary Gland Morphogenesis Cellular Response To Stimulus Positive Regulation Of Intracellular Signal Transduction Regulation Of Vasodilation Salivary Gland Development Metal Ion Homeostasis Positive Regulation Of Signal Transduction Isoleucine Catabolic Process Alkanesulfonate Metabolic Process Cerebellar Molecular Layer Development Positive Regulation Of Deoxyribonuclease Activity Skeletal Muscle Hypertrophy Meiotic Metaphase I Plate Congression ERBB2-ERBB3 Signaling Pathway Meiotic Spindle Midzone Assembly Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay	Platelet Degranulation Negative Regulation Of Ligand-dependent Nuclear Receptor Transcription Coactivator Activity Synaptic Growth At Neuromuscular Junction Release From Viral Latency Regulation Of Behavior Platelet Activation Collateral Sprouting In Absence Of Injury Fructose 1,6-bisphosphate Metabolic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Involved In Unfolded Protein Response Collateral Sprouting Axon Midline Choice Point Recognition Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Positive Regulation Of Deacetylase Activity Axon Choice Point Recognition Exocytosis Neuron Remodeling Establishment Of Viral Latency Positive Regulation Of Monocyte Chemotaxis Blood Coagulation Hemostasis Regulation Of Monocyte Chemotaxis Secretion By Cell Positive Regulation Of Defense Response To Virus By Host Cyclooxygenase Pathway Regulation Of Circadian Sleep/wake Cycle, Sleep Induction Of Positive Chemotaxis Cellular Copper Ion Homeostasis Fructose Metabolic Process Monocarboxylic Acid Metabolic Process Regulation Of Body Fluid Levels Small Molecule Metabolic Process Cytoplasmic Sequestering Of Transcription Factor Wound Healing Chemotaxis Prostaglandin Biosynthetic Process Copper Ion Homeostasis Suckling Behavior Regulation Of Growth Cellular Localization Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Cytoplasmic Sequestering Of Protein Secretion Negative Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway Muscle Cell Cellular Homeostasis Cell Activation Cellular Homeostasis Neuron Maturation MRNA Polyadenylation Regulation Of Epidermal Growth Factor-activated Receptor Activity Prostaglandin Metabolic Process
Tagcloud ?		actb aldr catb catd catg co3 conceptus cst6 gd1b gda gdi2 gsn hsp7c hsp90a hsp90a1 hspa8 idhc ifnt itraq phosphorylase pnp pnph ret4 rpb4 serpina31 tera timp2 ulf vcn
Tagcloud (Difference) ?		actb aldr catb catd catg co3 conceptus cst6 gd1b gda gdi2 gsn hsp7c hsp90a hsp90a1 hspa8 idhc ifnt itraq phosphorylase pnp pnph ret4 rpb4 serpina31 tera timp2 ulf vcn
Tagcloud (Intersection) ?