KRT75 and IQUB

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		KRT75	IQUB
Description		keratin 75	IQ motif and ubiquitin domain containing
Image		No pdb structure
GO Annotations	Cellular Component	Cornified Envelope Cytosol Intermediate Filament Keratin Filament Extracellular Exosome	Radial Spoke Acrosomal Vesicle Cytoplasm Cytoskeleton Cilium Motile Cilium Sperm Flagellum Cell Projection 9+2 Motile Cilium
	Molecular Function	Structural Molecule Activity Protein Binding Structural Constituent Of Skin Epidermis	Protein Binding
	Biological Process	Hematopoietic Progenitor Cell Differentiation Keratinization Intermediate Filament Organization	Smoothened Signaling Pathway Mating Cell Projection Organization Flagellated Sperm Motility Cilium Assembly
Pathways		Keratinization Formation of the cornified envelope
Drugs
Diseases		Pseudofolliculitis barbae
GWAS
Interacting Genes		119 interacting genes: - ABI2 AIRIM AMOT ANKS1A ARMC7 ASB15 BCAS2 BEX2 C19orf25 C1orf216 CAMK2A CARD10 CARD9 CATSPERT CCDC102B CCDC197 CCHCR1 CDC37 CDK18 CDKN2D CEP57 CFAP206 CPNE7 CRACR2A DHX15 DMAP1 DTNBP1 DYDC1 EFHC1 EPM2AIP1 FBXO17 FKBP6 GLYCTK GMCL1 GOLGA2 GOLGA6L9 GPANK1 HGS HNRNPF INCA1 IQUB KANK2 KCTD7 KIF9 KIFC3 KRT13 KRT20 KRT24 KRT25 KRT26 KRT27 KRT31 KRT32 KRT33B KRT34 KRT35 KRT36 KRT37 KRT38 KRT40 KRT76 LCA5L LMO1 LMO2 LMO4 LONRF1 MAGOHB MID2 MKRN3 MNS1 MTUS2 MYO15B MYOZ3 NCDN NDC80 NEK6 NFKBID NME7 NUDT21 NUP62 OIP5 OSGIN1 PLEKHG4 PM20D2 POLR1C POLR3C RCOR3 RSPH14 SCNM1 SMARCD1 SPAG5 SPTA1 STX11 SUFU TBC1D1 TCHP TEKT1 TEKT4 TJAP1 TNPO2 TNPO3 TRAF1 TRIM23 TRIM27 TRIM54 TRIML2 TSG101 TSSK3 TXLNA TXLNB U2AF1 USHBP1 WASHC1 WASHC3 WWOX XPOT ZNF76 ZWINT	58 interacting genes: ALX4 ANAPC11 ANKRD23 BLZF1 CALCOCO2 CEP70 CEP76 CFTR CYSRT1 DIP2A DYNLL1 EYA2 FAM107A GOLGA2 GPRASP3 IHO1 KATNAL1 KIFC3 KRT40 KRT75 KRT76 KRTAP10-3 KRTAP10-7 KRTAP10-9 KRTAP12-2 KRTAP12-4 LHX3 MAGEA6 MDFI PATZ1 PIH1D2 PIK3R3 PKP3 POU6F2 PRDM6 PRR23D1 PRR23D2 RHOH SAXO1 SMN1 SMN2 SORBS3 SYCE1 TMCC2 TP53BP2 TRAF2 TRAF6 TRIM23 TRIM27 TRIM42 TRIM50 TRIM54 TRIM55 TRIM63 ZNF143 ZNF410 ZNF526 ZRANB1
Entrez ID		9119	154865
HPRD ID		11057	08194
Ensembl ID		ENSG00000170454	ENSG00000164675
Uniprot IDs		O95678	Q8NA54
PDB IDs			2DAF 8J07
Enriched GO Terms of Interacting Partners?		Structural Constituent Of Skin Epidermis Intermediate Filament Organization Keratin Filament Intermediate Filament Cytoskeleton Organization Intermediate Filament-based Process Intermediate Filament Cytoskeleton Structural Molecule Activity Supramolecular Fiber Organization Cytoskeleton Organization Protein Binding Morphogenesis Of An Epithelium Epithelial Cell Differentiation Tissue Morphogenesis Motile Cilium Organelle Organization Axonemal A Tubule Inner Sheath Radial Spoke Microtubule-based Process Sperm Flagellum Axonemal Microtubule Cytoplasm Microtubule-based Movement Flagellated Sperm Motility Sperm Motility Cytosol Cilium-dependent Cell Motility Cilium Movement Cilium Movement Involved In Cell Motility Cilium Identical Protein Binding Microtubule Binding Regulation Of Actin Nucleation Microtubule Regulation Of Organelle Organization Spliceosomal Complex CBM Complex Centrosome Regulation Of Arp2/3 Complex-mediated Actin Nucleation Phosphatidylinositol 3-kinase Inhibitor Activity Polymeric Cytoskeletal Fiber Spindle Organization	Intermediate Filament Ubiquitin Protein Ligase Activity Keratin Filament Identical Protein Binding Zinc Ion Binding Protein Binding Protein K63-linked Ubiquitination Microtubule Ubiquitin-protein Transferase Activity
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