ZNF774 and IPO8

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		ZNF774	IPO8
Description		zinc finger protein 774	importin 8
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus	Nucleus Nuclear Envelope Nucleoplasm Cytoplasm Cytosol
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Protein Binding Zinc Ion Binding Metal Ion Binding	Protein Binding Small GTPase Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II	Protein Import Into Nucleus Intracellular Protein Transport Signal Transduction Protein Transport
Pathways		Generic Transcription Pathway	Transcriptional regulation by small RNAs
Drugs
Diseases
GWAS		Male-pattern baldness ( 28196072) Rheumatoid arthritis ( 22446963)	Initial pursuit acceleration ( 29064472) Initial pursuit acceleration in psychotic disorders ( 29064472) Monocyte count ( 32888494) Order dimension in obsessive compulsive disorder ( 32424139) Response to selenium supplementation (change in plasma selenium concentration) ( 33382417)
Interacting Genes		77 interacting genes: BACH2 BEGAIN BLK BOLA2 BOLA2B CABP2 CALCOCO2 CARD9 CATSPER1 CCDC102B CCDC136 CCDC6 CCHCR1 CDK18 CDKN2D CEP63 CIB3 COL8A1 CPNE7 DTX2 DVL3 EFEMP2 EMD FAM124B FSD2 GABARAPL2 GEM GFAP GLRX3 GOLGA1 GOLGA2 GTPBP3 GYS1 GZMM HOXA1 HOXB5 HSF2BP IL16 IPO8 KANK2 KIFC3 KRTAP10-6 KRTAP10-7 KRTAP10-9 KRTAP4-5 LDOC1 LONRF1 MAGOHB MID2 MLH1 MTUS2 MYO15B NDOR1 NEK6 NID2 PIBF1 PICK1 PRPF31 PSMB1 RABEP1 RAD51D RBM11 SCNM1 SH2D4A SMAD3 STK16 TRAF2 TSTD2 USP49 VWC2 YJU2B ZNF165 ZNF417 ZNF48 ZNF526 ZNF572 ZNF587	12 interacting genes: ATXN1 EIF4E KPNB1 LRPPRC RAN RANGAP1 RNF10 SRP19 WT1 ZFP2 ZNF264 ZNF774
Entrez ID		342132	10526
HPRD ID		17571	09282
Ensembl ID		ENSG00000196391	ENSG00000133704
Uniprot IDs		Q6NX45	O15397
PDB IDs
Enriched GO Terms of Interacting Partners?		Protein Binding Iron-sulfur Cluster Assembly [2Fe-2S] Cluster Assembly Iron-sulfur Cluster Assembly Complex	Nuclear Transport Nucleocytoplasmic Transport Nuclear Export RNA Binding RNA Transport RNA Import Into Nucleus Nucleus Nucleobase-containing Compound Transport Importin-alpha Family Protein Binding Cellular Localization Nuclear Pore Intracellular Transport Cellular Response To Hormone Stimulus DNA Binding Establishment Of Localization In Cell Nuclear Envelope Regulation Of Glial Cell Proliferation Regulation Of RNA Metabolic Process Eukaryotic Initiation Factor 4G Binding Response To Hormone Negative Regulation Of Metanephric Glomerular Mesangial Cell Proliferation Establishment Of Organelle Localization Regulation Of Macromolecule Biosynthetic Process Regulation Of Primary Metabolic Process Cellular Response To Corticosteroid Stimulus Regulation Of Gene Expression Regulation Of Nucleobase-containing Compound Metabolic Process Zinc Ion Binding RNA Nuclear Export Complex SnRNA Import Into Nucleus Pre-miRNA Export From Nucleus Cytoplasmic Periphery Of The Nuclear Pore Complex Adrenal Cortex Formation Positive Regulation Of Metanephric Ureteric Bud Development Visceral Serous Pericardium Development Posterior Mesonephric Tubule Development Negative Regulation Of Mitochondrial MRNA Catabolic Process Negative Regulation Of Mitochondrial RNA Catabolic Process RNA Export From Nucleus Establishment Of Protein Localization To Organelle Cellular Response To Steroid Hormone Stimulus Cytoplasmic Stress Granule Mitotic Spindle Organization Regulation Of Translation At Postsynapse, Modulating Synaptic Transmission Negative Regulation Of Female Gonad Development Negative Regulation Of Glomerular Mesangial Cell Proliferation MRNA Cap Binding Regulation Of Macromolecule Metabolic Process Regulation Of Translation Regulation Of Translation At Postsynapse
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