IPO8

Description		importin 8
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nuclear Envelope Nucleoplasm Cytoplasm Cytosol
	Molecular Function	Protein Binding Small GTPase Binding
	Biological Process	Protein Import Into Nucleus Intracellular Protein Transport Signal Transduction Protein Transport
Pathways		Transcriptional regulation by small RNAs
Drugs
Diseases
GWAS		Initial pursuit acceleration ( 29064472) Initial pursuit acceleration in psychotic disorders ( 29064472) Monocyte count ( 32888494) Order dimension in obsessive compulsive disorder ( 32424139) Response to selenium supplementation (change in plasma selenium concentration) ( 33382417)
Interacting Genes		12 interacting genes: ATXN1 EIF4E KPNB1 LRPPRC RAN RANGAP1 RNF10 SRP19 WT1 ZFP2 ZNF264 ZNF774
Entrez ID		10526
HPRD ID		09282
Ensembl ID		ENSG00000133704
Uniprot IDs		O15397
PDB IDs
Enriched GO Terms of Interacting Partners?		Nuclear Transport Nucleocytoplasmic Transport Nuclear Export RNA Binding RNA Transport RNA Import Into Nucleus Nucleus Nucleobase-containing Compound Transport Importin-alpha Family Protein Binding Cellular Localization Nuclear Pore Intracellular Transport Cellular Response To Hormone Stimulus DNA Binding Establishment Of Localization In Cell Nuclear Envelope Regulation Of Glial Cell Proliferation Regulation Of RNA Metabolic Process Eukaryotic Initiation Factor 4G Binding Response To Hormone Negative Regulation Of Metanephric Glomerular Mesangial Cell Proliferation Establishment Of Organelle Localization Regulation Of Macromolecule Biosynthetic Process Regulation Of Primary Metabolic Process Cellular Response To Corticosteroid Stimulus Regulation Of Gene Expression Regulation Of Nucleobase-containing Compound Metabolic Process Zinc Ion Binding RNA Nuclear Export Complex SnRNA Import Into Nucleus Pre-miRNA Export From Nucleus Cytoplasmic Periphery Of The Nuclear Pore Complex Adrenal Cortex Formation Positive Regulation Of Metanephric Ureteric Bud Development Visceral Serous Pericardium Development Posterior Mesonephric Tubule Development Negative Regulation Of Mitochondrial MRNA Catabolic Process Negative Regulation Of Mitochondrial RNA Catabolic Process RNA Export From Nucleus Establishment Of Protein Localization To Organelle Cellular Response To Steroid Hormone Stimulus Cytoplasmic Stress Granule Mitotic Spindle Organization Regulation Of Translation At Postsynapse, Modulating Synaptic Transmission Negative Regulation Of Female Gonad Development Negative Regulation Of Glomerular Mesangial Cell Proliferation MRNA Cap Binding Regulation Of Macromolecule Metabolic Process Regulation Of Translation Regulation Of Translation At Postsynapse
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