ZNF774 and TSTD2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		ZNF774	TSTD2
Description		zinc finger protein 774	thiosulfate sulfurtransferase like domain containing 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Protein Binding Zinc Ion Binding Metal Ion Binding	Protein Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II
Pathways		Generic Transcription Pathway
Drugs
Diseases
GWAS		Male-pattern baldness ( 28196072) Rheumatoid arthritis ( 22446963)
Interacting Genes		77 interacting genes: BACH2 BEGAIN BLK BOLA2 BOLA2B CABP2 CALCOCO2 CARD9 CATSPER1 CCDC102B CCDC136 CCDC6 CCHCR1 CDK18 CDKN2D CEP63 CIB3 COL8A1 CPNE7 DTX2 DVL3 EFEMP2 EMD FAM124B FSD2 GABARAPL2 GEM GFAP GLRX3 GOLGA1 GOLGA2 GTPBP3 GYS1 GZMM HOXA1 HOXB5 HSF2BP IL16 IPO8 KANK2 KIFC3 KRTAP10-6 KRTAP10-7 KRTAP10-9 KRTAP4-5 LDOC1 LONRF1 MAGOHB MID2 MLH1 MTUS2 MYO15B NDOR1 NEK6 NID2 PIBF1 PICK1 PRPF31 PSMB1 RABEP1 RAD51D RBM11 SCNM1 SH2D4A SMAD3 STK16 TRAF2 TSTD2 USP49 VWC2 YJU2B ZNF165 ZNF417 ZNF48 ZNF526 ZNF572 ZNF587	33 interacting genes: AGR2 APC AURKA BLZF1 BUB1 CCND1 DCC EGFR FLCN IKZF1 IKZF3 INCA1 ISY1-RAB43 L3MBTL3 LHX4 MCC MEOX2 MLH3 MUTYH ODC1 PICK1 PTPRJ REL SMAD4 SSX2IP TCF4 TOX3 VPS52 ZBTB14 ZFPL1 ZNF438 ZNF774 ZRANB1
Entrez ID		342132	158427
HPRD ID		17571	16679
Ensembl ID		ENSG00000196391	ENSG00000136925
Uniprot IDs		Q6NX45	Q5T7W7
PDB IDs
Enriched GO Terms of Interacting Partners?		Protein Binding Iron-sulfur Cluster Assembly [2Fe-2S] Cluster Assembly Iron-sulfur Cluster Assembly Complex	Nucleus Nucleoplasm Regulation Of Primary Metabolic Process Regulation Of Macromolecule Metabolic Process Negative Regulation Of Protein Serine/threonine Kinase Activity Sequence-specific DNA Binding DNA-binding Transcription Factor Activity Regulation Of Programmed Cell Death Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Transcription By RNA Polymerase II DNA Binding Negative Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Mesoderm Development DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Negative Regulation Of Cyclin-dependent Protein Kinase Activity Regulation Of Metabolic Process Regulation Of Apoptotic Process Negative Regulation Of Phosphate Metabolic Process Gamma-catenin Binding Response To UV-A Regulation Of RNA Metabolic Process Regulation Of Gene Expression Negative Regulation Of Cardiocyte Differentiation Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Negative Regulation Of Cellular Component Organization Regulation Of Wnt Signaling Pathway Negative Regulation Of Protein Kinase Activity Regulation Of Macromolecule Biosynthetic Process Regulation Of ERBB Signaling Pathway RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Regulation Of Mitotic Cell Cycle Phase Transition Negative Regulation Of Kinase Activity Cellular Developmental Process Protein-containing Complex Binding Negative Regulation Of Macromolecule Metabolic Process Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Protein Catabolic Process Developmental Process Digestive Tract Morphogenesis Regulation Of Cell Population Proliferation Negative Regulation Of Protein Metabolic Process Neuron Projection Guidance Axon Guidance Ruffle Membrane Heart Valve Development Beta-catenin Binding Animal Organ Development Negative Regulation Of Protein Phosphorylation Negative Regulation Of Metabolic Process
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