IPO8 and RANGAP1

Number of citations of the paper that reports this interaction (PMID 9214382)
144

Data Source:
HPRD (in vitro)

		IPO8	RANGAP1
Gene Name		importin 8	Ran GTPase activating protein 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm Cytosol	Kinetochore Condensed Chromosome Kinetochore Spindle Pole Nuclear Pore Cytoplasm Cytosol Nuclear Membrane Perinuclear Region Of Cytoplasm
	Molecular Function	Protein Binding Ran GTPase Binding	Ran GTPase Activator Activity Protein Binding
	Biological Process	Intracellular Protein Transport Signal Transduction Gene Expression	Mitotic Cell Cycle Signal Transduction Positive Regulation Of Ran GTPase Activity Negative Regulation Of Protein Export From Nucleus
Pathways		Transcriptional regulation by small RNAs Regulatory RNA pathways	Mitotic Prometaphase Separation of Sister Chromatids HIV Infection Host Interactions of HIV factors Rev-mediated nuclear export of HIV RNA Mitotic Anaphase Interactions of Rev with host cellular proteins M Phase Cell Cycle, Mitotic Late Phase of HIV Life Cycle HIV Life Cycle Rev-mediated nuclear export of HIV RNA Resolution of Sister Chromatid Cohesion Mitotic Metaphase and Anaphase
Drugs
Diseases
GWAS
Protein-Protein Interactions		4 interactors: ATXN1 KPNB1 RANGAP1 SRP19	14 interactors: CCL5 CSNK2A1 GNAI1 GNAI3 IPO8 RAN RANBP2 SENP1 SENP2 SUMO1 SUMO2 SUMO3 UBE2I USPL1
Entrez ID		10526	5905
HPRD ID		09282	03839
Ensembl ID		ENSG00000133704	ENSG00000100401
Uniprot IDs		O15397	F8W7I9 P46060 Q9BSK3
PDB IDs			1Z5S 2GRN 2GRO 2GRP 2GRQ 2GRR 2IO2 2IO3 2IY0 3UIN 3UIO 3UIP
Enriched GO Terms of Interacting Partners?		Cytoplasmic Transport Nucleocytoplasmic Transport Nuclear Transport Positive Regulation Of Ran GTPase Activity Intracellular Transport Negative Regulation Of Protein Export From Nucleus Ribosomal Protein Import Into Nucleus Establishment Of Protein Localization To Organelle Negative Regulation Of Insulin-like Growth Factor Receptor Signaling Pathway Protein Targeting Establishment Of Localization In Cell Protein Localization To Organelle Apoptotic DNA Fragmentation NLS-bearing Protein Import Into Nucleus Regulation Of Insulin-like Growth Factor Receptor Signaling Pathway Cellular Localization Intracellular Transport Of Virus Protein Import Into Nucleus, Translocation Apoptotic Nuclear Changes Regulation Of Protein Export From Nucleus	Protein Sumoylation Peptidyl-lysine Modification Protein Desumoylation Post-translational Protein Modification Peptidyl-amino Acid Modification Protein Modification By Small Protein Conjugation Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Cellular Protein Modification Process Regulation Of Protein Catabolic Process Protein Localization To Nucleus Positive Regulation Of Protein Metabolic Process Regulation Of Proteasomal Protein Catabolic Process Positive Regulation Of Protein Catabolic Process Cellular Protein Metabolic Process Positive Regulation Of Proteolysis Positive Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Metabolic Process Regulation Of Proteolysis Protein Modification By Small Protein Removal Nucleus Organization Regulation Of Cellular Protein Metabolic Process Cell Cycle Positive Regulation Of Proteolysis Involved In Cellular Protein Catabolic Process Negative Regulation Of Cellular Metabolic Process Cell Division Positive Regulation Of Cellular Protein Catabolic Process Regulation Of Protein Metabolic Process Signal Transduction Protein Localization To Organelle Protein Metabolic Process Signaling Cell Communication Positive Regulation Of Cellular Metabolic Process Regulation Of Metabolic Process Regulation Of Binding Vesicle Fusion Protein Localization Metabolic Process Mitotic Cell Cycle Process Adenylate Cyclase-inhibiting G-protein Coupled Receptor Signaling Pathway Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of SUMO Transferase Activity Negative Regulation Of Proteasomal Protein Catabolic Process Nuclear Envelope Organization Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Cellular Protein Localization Mitotic Cell Cycle Positive Regulation Of Proteasomal Protein Catabolic Process Cellular Response To Stimulus Negative Regulation Of Cellular Protein Catabolic Process
Tagcloud ?		actb algorithms analyzing arachnoidea bestkeeper casc3 chosen deltact dura eif2b1 gapdh genorm housekeeping integration mater meningiomas mrpl19 normalization normfinder pgk1 pop4 ppia qpcr ranked reference rpl37a software validate vegfa	apl bodies compartmentalisation covalently dependant disrupted fits indirectly kr leukaemia localisation localises lys487 lys490 modification modifies mutagenesis named nd10 phosphoprotein pic1 pml pods promyelocytic rara subcellular sumo translocated ubc9
Tagcloud (Difference) ?		actb algorithms analyzing arachnoidea bestkeeper casc3 chosen deltact dura eif2b1 gapdh genorm housekeeping integration mater meningiomas mrpl19 normalization normfinder pgk1 pop4 ppia qpcr ranked reference rpl37a software validate vegfa	apl bodies compartmentalisation covalently dependant disrupted fits indirectly kr leukaemia localisation localises lys487 lys490 modification modifies mutagenesis named nd10 phosphoprotein pic1 pml pods promyelocytic rara subcellular sumo translocated ubc9
Tagcloud (Intersection) ?