CPLX4 and CLEC4G

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		CPLX4	CLEC4G
Description		complexin 4	C-type lectin domain family 4 member G
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Membrane SNARE Complex Terminal Bouton Synapse	Plasma Membrane External Side Of Plasma Membrane Membrane
	Molecular Function	SNARE Binding Protein Binding Syntaxin Binding	Virus Receptor Activity Protein Binding D-mannose Binding Carbohydrate Binding Polysaccharide Binding Pattern Recognition Receptor Activity Fructose Binding Carbohydrate Derivative Binding Virus Coreceptor Activity Glycosylated Region Protein Binding
	Biological Process	Neurotransmitter Transport Exocytosis Visual Perception Synaptic Vesicle Exocytosis Regulation Of Synaptic Vesicle Fusion To Presynaptic Active Zone Membrane Regulation Of Neurotransmitter Secretion Modulation Of Chemical Synaptic Transmission	T Cell Mediated Immunity Negative Regulation Of T Cell Mediated Immunity Immune Response Immature T Cell Proliferation In Thymus Negative Regulation Of Immature T Cell Proliferation In Thymus Negative Regulation Of T Cell Proliferation Alpha-beta T Cell Proliferation Negative Regulation Of Alpha-beta T Cell Proliferation Symbiont Entry Into Host Cell Positive Regulation Of Viral Life Cycle
Pathways			Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
Drugs
Diseases
GWAS		Cardiac troponin-I levels ( 31014085) Chronotype ( 27494321) Macular thickness ( 30535121) Morning vs. evening chronotype ( 27494321)	Post bronchodilator FEV1 ( 26634245)
Interacting Genes		100 interacting genes: ADIPOQ AGTRAP AIG1 AOC3 APOD AQP1 AQP9 ASGR1 ATP6V0C BMP10 BNIP2 C14orf180 C1GALT1 C3orf52 C5 CACNG1 CCL4L2 CD81 CDIPT CDS2 CLDND2 CLEC4G CLN6 CMTM5 CNIH1 CTSA CTXN3 CYB5B CYBC1 CYP4F2 DEFB127 EMD GAD2 GIMAP1 GRM2 HACD1 HHATL HMOX1 IGFBP5 INSIG2 LHFPL5 LPAR3 MAL MALL MAN2B2 MGAM NINJ2 NRM ORMDL1 PGAP2 PLN PLP2 PLPP4 PNLIPRP1 PTPN9 RTP2 SEC22B SELENOK SFTPC SLC30A2 SLC30A8 SLC35A1 SLC35A4 SLC35B4 SLC38A7 SLC39A9 SMCO4 SMIM1 SNCA STX3 STX8 SYNJ2BP TF TMEM107 TMEM120B TMEM128 TMEM14A TMEM14B TMEM19 TMEM201 TMEM203 TMEM218 TMEM229B TMEM243 TMEM254 TMEM267 TMEM42 TMEM60 TMEM79 TMEM86A TMEM97 TRAF3IP3 TSPO2 UBIAD1 VAMP4 VAMP5 VKORC1 WFDC2 YIPF6 ZFPL1	27 interacting genes: APOA1 APOH ARL13B ARSA ASGR1 AZU1 CAPN1 CPLX4 CPN1 EBAG9 EIF6 FAM209A FTL GEM IFI35 LRRC4C MAP3K11 MT-CO1 NUP214 PKLR PRDX1 PTPN5 RPSA SHBG SIGLEC12 TNFAIP3 WBP2
Entrez ID		339302	339390
HPRD ID		13091	16721
Ensembl ID		ENSG00000166569	ENSG00000182566
Uniprot IDs		Q7Z7G2	B7ZKQ2 Q08G24 Q6UXB4 Q6XYD1
PDB IDs
Enriched GO Terms of Interacting Partners?		Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Protein Binding Chemical Homeostasis Golgi Membrane Cholesterol Binding Intracellular Chemical Homeostasis Monoatomic Cation Homeostasis Pyrimidine Nucleotide-sugar Transmembrane Transport Monoatomic Ion Homeostasis Nucleotide-sugar Transmembrane Transport Homeostatic Process Vitamin K Metabolic Process Negative Regulation Of Platelet-derived Growth Factor Receptor Signaling Pathway Golgi Apparatus Spindle Pole Centrosome Cellular Homeostasis Hydrogen Peroxide Channel Activity Negative Regulation Of Chaperone-mediated Autophagy Intracellular Monoatomic Cation Homeostasis Intracellular Monoatomic Ion Homeostasis Inorganic Ion Homeostasis Hydrogen Peroxide Transmembrane Transport Nuclear Inner Membrane Respiratory Burst After Phagocytosis Regulation Of Chemokine Production Negative Regulation Of Lipoprotein Metabolic Process Cellular Response To CAMP Zinc:proton Antiporter Activity Zinc Ion Transmembrane Transporter Activity Pyrimidine Nucleotide-sugar Transmembrane Transporter Activity Negative Regulation Of Smooth Muscle Cell Proliferation Regulation Of Platelet-derived Growth Factor Receptor Signaling Pathway Zinc Ion Transmembrane Transport Menaquinone Metabolic Process Lysosome Zinc Ion Transport Glycerol Transmembrane Transport Multicellular Organismal-level Chemical Homeostasis Intracellular Zinc Ion Homeostasis Positive Regulation Of Chemokine Production Cortical Endoplasmic Reticulum Regulation Of Chaperone-mediated Autophagy Endomembrane System Long-chain Fatty Acid Catabolic Process Regulation Of Cellular Localization	Extracellular Exosome
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