CENATAC and MRPL38

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		CENATAC	MRPL38
Description		centrosomal AT-AC splicing factor	mitochondrial ribosomal protein L38
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GO Annotations	Cellular Component	Cytoplasm Centrosome Cytoskeleton	Mitochondrion Mitochondrial Inner Membrane Mitochondrial Large Ribosomal Subunit Cytosol Ribosome Ribonucleoprotein Complex
	Molecular Function	Protein Binding	Protein Binding
	Biological Process	MRNA Splicing, Via Spliceosome MRNA Processing RNA Splicing Negative Regulation Of Centrosome Duplication Regulation Of Protein Catabolic Process Chromosome Separation	Mitochondrial Translation
Pathways			Mitochondrial translation initiation Mitochondrial translation elongation Mitochondrial translation elongation Mitochondrial translation termination Mitochondrial ribosome-associated quality control
Drugs
Diseases
GWAS			White matter hyperintensities ( 30002152)
Interacting Genes		7 interacting genes: MESD MRPL38 NAT10 NDOR1 PPIL3 SIRT1 ZNF114	21 interacting genes: ARHGAP9 BAG3 BEX2 BTG3 CCDC120 CENATAC CSNK2A1 DOCK8 ENKD1 ERCC6 ERG28 GOLGA6A HSPB3 LONRF1 MKRN3 MYOZ3 PPP1R18 PRIM1 RALY TSEN54 UBC
Entrez ID		338657	64978
HPRD ID		13234	14758
Ensembl ID		ENSG00000186166	ENSG00000204316
Uniprot IDs		Q86UT8	Q96DV4
PDB IDs		8Y6O	3J7Y 3J9M 5OOL 5OOM 6I9R 6NU2 6NU3 6VLZ 6VMI 6ZM5 6ZM6 6ZS9 6ZSA 6ZSB 6ZSC 6ZSD 6ZSE 6ZSG 7A5F 7A5G 7A5H 7A5I 7A5J 7A5K 7L08 7L20 7O9K 7O9M 7ODR 7ODS 7ODT 7OF0 7OF2 7OF3 7OF4 7OF5 7OF6 7OF7 7OG4 7OI6 7OI7 7OI8 7OI9 7OIA 7OIB 7OIC 7OID 7OIE 7PD3 7PO4 7QH6 7QH7 7QI4 7QI5 7QI6 8ANY 8K2A 8K2B 8OIR 8OIT 8PK0 8QSJ 8QU1 8QU5 8RRI 8XT0 8XT1 8XT2 8XT3
Enriched GO Terms of Interacting Partners?		Regulation Of Centrosome Cycle NAD-dependent Protein Decrotonylase Activity Histone H4K12 Deacetylase Activity, Hydrolytic Mechanism Protein Acetylation Negative Regulation Of Attachment Of Mitotic Spindle Microtubules To Kinetochore Regulation Of Centrosome Duplication Maintenance Of Nucleus Location Histone Decrotonylase Activity, NAD-dependent Histone H3K14 Deacetylase Activity, NAD-dependent Negative Regulation Of Cellular Response To Testosterone Stimulus Histone H3K Deacetylase Activity NADPH-iron-sulfur [2Fe-2S] Protein Oxidoreductase Activity TRNA Acetylation MRNA N-acetyltransferase Activity TRNA Cytidine N4-acetyltransferase Activity TRNA Wobble Cytosine Modification RRNA Acetylation Involved In Maturation Of SSU-rRNA 18S RRNA Cytidine N-acetyltransferase Activity NAD-dependent Protein Lysine Delactylase Activity Regulation Of Cellular Response To Testosterone Stimulus Behavioral Response To Starvation Negative Regulation Of Peptidyl-lysine Acetylation Histone H4K16 Deacetylase Activity, NAD-dependent Histone H3K9 Deacetylase Activity, NAD-dependent NAD-dependent Protein-lysine Depropionylase Activity Negative Regulation Of Prostaglandin Biosynthetic Process Protein Depropionylation Positive Regulation Of Macrophage Apoptotic Process ENoSc Complex Positive Regulation Of CAMP-dependent Protein Kinase Activity NADPH-hemoprotein Reductase Activity Negative Regulation Of Protein Acetylation Negative Regulation Of Triglyceride Biosynthetic Process Triglyceride Mobilization Pyrimidine Dimer Repair By Nucleotide-excision Repair HLH Domain Binding Oxidoreductase Activity, Acting On NAD(P)H, Heme Protein As Acceptor Histone Deacetylase Activity, NAD-dependent Regulation Of CAMP-dependent Protein Kinase Activity RDNA Heterochromatin Chromosome, Telomeric Region Keratin Filament Binding Protein Folding RDNA Heterochromatin Formation Regulation Of Endodeoxyribonuclease Activity Stress-induced Premature Senescence NAD-dependent Protein Lysine Deacetylase Activity Regulation Of Skeletal Muscle Acetylcholine-gated Channel Clustering Positive Regulation Of Skeletal Muscle Acetylcholine-gated Channel Clustering Ovulation From Ovarian Follicle	Positive Regulation Of Aggrephagy Double-strand Break Repair Via Classical Nonhomologous End Joining
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