CENATAC and NDOR1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		CENATAC	NDOR1
Description		centrosomal AT-AC splicing factor	NADPH dependent diflavin oxidoreductase 1
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GO Annotations	Cellular Component	Cytoplasm Centrosome Cytoskeleton	Nucleus Nucleoplasm Cytoplasm Cytosol Intermediate Filament Cytoskeleton Perinuclear Region Of Cytoplasm
	Molecular Function	Protein Binding	NADPH-hemoprotein Reductase Activity Protein Binding Electron Transfer Activity FMN Binding Oxidoreductase Activity Oxidoreductase Activity, Acting On NAD(P)H Oxidoreductase Activity, Acting On NAD(P)H, Heme Protein As Acceptor Flavin Adenine Dinucleotide Binding NADP Binding NADPH Binding FAD Binding NADPH-iron-sulfur [2Fe-2S] Protein Oxidoreductase Activity
	Biological Process	MRNA Splicing, Via Spliceosome MRNA Processing RNA Splicing Negative Regulation Of Centrosome Duplication Regulation Of Protein Catabolic Process Chromosome Separation	Iron-sulfur Cluster Assembly Electron Transport Chain
Pathways			Cytosolic iron-sulfur cluster assembly
Drugs
Diseases
GWAS			Estimated glomerular filtration rate ( 31152163) High light scatter reticulocyte count ( 27863252 32888494) High light scatter reticulocyte percentage of red cells ( 27863252 32888494) Immature fraction of reticulocytes ( 32888494) Mean corpuscular hemoglobin ( 27863252 32888494) Mean corpuscular hemoglobin concentration ( 27863252 32888494) Mean corpuscular volume ( 27863252 32888494) Mean spheric corpuscular volume ( 32888494) Red blood cell count ( 32888494) Reticulocyte count ( 27863252 32888494) Reticulocyte fraction of red cells ( 27863252 32888494)
Interacting Genes		7 interacting genes: MESD MRPL38 NAT10 NDOR1 PPIL3 SIRT1 ZNF114	29 interacting genes: C7orf57 CCDC33 CENATAC CYCS DLG4 DRC4 EFHC2 ENOX2 GPS2 HOXB2 KIAA0408 LMO2 LMO3 LNX1 MEOX1 MTUS2 NAB2 NLK PSMB6 TCF4 TCHP TEPSIN TLE5 UBQLN1 UBQLN2 ZBTB42 ZC2HC1C ZNF620 ZNF774
Entrez ID		338657	27158
HPRD ID		13234	10444
Ensembl ID		ENSG00000186166	ENSG00000188566
Uniprot IDs		Q86UT8	Q9UHB4
PDB IDs		8Y6O	4H2D
Enriched GO Terms of Interacting Partners?		Regulation Of Centrosome Cycle NAD-dependent Protein Decrotonylase Activity Histone H4K12 Deacetylase Activity, Hydrolytic Mechanism Protein Acetylation Negative Regulation Of Attachment Of Mitotic Spindle Microtubules To Kinetochore Regulation Of Centrosome Duplication Maintenance Of Nucleus Location Histone Decrotonylase Activity, NAD-dependent Histone H3K14 Deacetylase Activity, NAD-dependent Negative Regulation Of Cellular Response To Testosterone Stimulus Histone H3K Deacetylase Activity NADPH-iron-sulfur [2Fe-2S] Protein Oxidoreductase Activity TRNA Acetylation MRNA N-acetyltransferase Activity TRNA Cytidine N4-acetyltransferase Activity TRNA Wobble Cytosine Modification RRNA Acetylation Involved In Maturation Of SSU-rRNA 18S RRNA Cytidine N-acetyltransferase Activity NAD-dependent Protein Lysine Delactylase Activity Regulation Of Cellular Response To Testosterone Stimulus Behavioral Response To Starvation Negative Regulation Of Peptidyl-lysine Acetylation Histone H4K16 Deacetylase Activity, NAD-dependent Histone H3K9 Deacetylase Activity, NAD-dependent NAD-dependent Protein-lysine Depropionylase Activity Negative Regulation Of Prostaglandin Biosynthetic Process Protein Depropionylation Positive Regulation Of Macrophage Apoptotic Process ENoSc Complex Positive Regulation Of CAMP-dependent Protein Kinase Activity NADPH-hemoprotein Reductase Activity Negative Regulation Of Protein Acetylation Negative Regulation Of Triglyceride Biosynthetic Process Triglyceride Mobilization Pyrimidine Dimer Repair By Nucleotide-excision Repair HLH Domain Binding Oxidoreductase Activity, Acting On NAD(P)H, Heme Protein As Acceptor Histone Deacetylase Activity, NAD-dependent Regulation Of CAMP-dependent Protein Kinase Activity RDNA Heterochromatin Chromosome, Telomeric Region Keratin Filament Binding Protein Folding RDNA Heterochromatin Formation Regulation Of Endodeoxyribonuclease Activity Stress-induced Premature Senescence NAD-dependent Protein Lysine Deacetylase Activity Regulation Of Skeletal Muscle Acetylcholine-gated Channel Clustering Positive Regulation Of Skeletal Muscle Acetylcholine-gated Channel Clustering Ovulation From Ovarian Follicle
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