APLP2 and ADIPOR1

Number of citations of the paper that reports this interaction (PMID 16622416)
118

Data Source:
BioGRID (two hybrid)

		APLP2	ADIPOR1
Gene Name		amyloid beta (A4) precursor-like protein 2	adiponectin receptor 1
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Plasma Membrane Membrane Integral Component Of Membrane Extracellular Vesicular Exosome	Plasma Membrane Membrane Integral Component Of Membrane
	Molecular Function	DNA Binding Serine-type Endopeptidase Inhibitor Activity Protein Binding Heparin Binding Identical Protein Binding Transition Metal Ion Binding	Receptor Activity Protein Kinase Binding Hormone Binding Identical Protein Binding Protein Heterodimerization Activity Adiponectin Binding
	Biological Process	Suckling Behavior Cellular Copper Ion Homeostasis Regulation Of Epidermal Growth Factor-activated Receptor Activity G-protein Coupled Receptor Signaling Pathway Mating Behavior Locomotory Behavior Cholesterol Metabolic Process Negative Regulation Of Endopeptidase Activity Extracellular Matrix Organization Forebrain Development Midbrain Development Regulation Of Protein Binding Neuromuscular Process Controlling Balance	Hormone-mediated Signaling Pathway Fatty Acid Oxidation Negative Regulation Of Cell Growth Leptin-mediated Signaling Pathway Adiponectin-activated Signaling Pathway Positive Regulation Of JAK-STAT Cascade Positive Regulation Of Insulin Receptor Signaling Pathway
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		23 interactors: ADIPOR1 AKT1 APBB1 APBB2 APBB3 BRCA1 CDK1 DAB1 DAB2 DEDD ETS1 HGS HLA-A JUN JUNB KAT5 MAPK8 PIK3CA PRKCA PRNP RPL26 VKORC1 ZNF512B	5 interactors: APLP2 APPL1 DPH3 NAA20 NFKBIL1
Entrez ID		334	51094
HPRD ID		00103	06402
Ensembl ID		ENSG00000084234	ENSG00000159346
Uniprot IDs		B4E3I5 Q06481	Q96A54
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Apoptotic Process Regulation Of Cell Death Regulation Of Protein Metabolic Process Negative Regulation Of Apoptotic Process Negative Regulation Of Programmed Cell Death Regulation Of Cell Cycle Response To Radiation Negative Regulation Of Cell Death Cellular Response To Organic Substance Cellular Response To Growth Factor Stimulus Positive Regulation Of Gene Expression Response To Growth Factor Cellular Response To Stimulus Regulation Of Nitrogen Compound Metabolic Process Response To Organic Substance Apoptotic Process Response To Cytokine Signal Transduction Programmed Cell Death Response To External Stimulus Cell Death Response To Stimulus Death Positive Regulation Of Metabolic Process Response To Stress Intracellular Signal Transduction Response To Abiotic Stimulus Epidermal Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Signaling Regulation Of Gene Expression Regulation Of Cellular Protein Metabolic Process Regulation Of Metabolic Process Cell Communication Regulation Of Transcription, DNA-templated Apoptotic Signaling Pathway Regulation Of Nucleic Acid-templated Transcription Positive Regulation Of Cellular Biosynthetic Process Regulation Of RNA Biosynthetic Process Leading Edge Cell Differentiation Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Immune System Process Regulation Of Growth Enzyme Linked Receptor Protein Signaling Pathway Positive Regulation Of Protein Modification Process Regulation Of RNA Metabolic Process Regulation Of Cell Adhesion Regulation Of Immune System Process Neurotrophin TRK Receptor Signaling Pathway Response To Hormone	Regulation Of Establishment Of Protein Localization Regulation Of Protein Localization Negative Regulation Of Protein Transport Regulation Of Cellular Localization N-terminal Peptidyl-methionine Acetylation Regulation Of Binding Negative Regulation Of Lipopolysaccharide-mediated Signaling Pathway Peptidyl-methionine Modification N-terminal Protein Amino Acid Acetylation Negative Regulation Of Transport Peptidyl-diphthamide Biosynthetic Process From Peptidyl-histidine
Tagcloud ?		allowed app backgroundamyloid conclusionsthe cooperative fertility interacting interactome male members modules motility network networks ontologyand oocyte outside playing reproduction reproductive resultswe screen shed specified sperm spermatozoa superfamily testis topological	activate ampk appreciated benign decreases depletion endothelial healthy hyperplasia inhibit mtor neovascularization plasma prostate prostatic remain resected seemed specimen subjects suppressing taken tsc2 tumorigenesis underlying unknown vascular vegf
Tagcloud (Difference) ?		allowed app backgroundamyloid conclusionsthe cooperative fertility interacting interactome male members modules motility network networks ontologyand oocyte outside playing reproduction reproductive resultswe screen shed specified sperm spermatozoa superfamily testis topological	activate ampk appreciated benign decreases depletion endothelial healthy hyperplasia inhibit mtor neovascularization plasma prostate prostatic remain resected seemed specimen subjects suppressing taken tsc2 tumorigenesis underlying unknown vascular vegf
Tagcloud (Intersection) ?