APBA1 and CNTNAP3

Number of citations of the paper that reports this interaction (PubMedID 12093160)
0

Data Source:
HPRD (in vitro, in vivo)

		APBA1	CNTNAP3
Description		amyloid beta precursor protein binding family A member 1	contactin associated protein family member 3
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Golgi Apparatus Cytosol Plasma Membrane Synaptic Vesicle Membrane Dendritic Spine Perinuclear Region Of Cytoplasm Presynaptic Active Zone Membrane Schaffer Collateral - CA1 Synapse Glutamatergic Synapse	Extracellular Region Plasma Membrane Membrane
	Molecular Function	Amyloid-beta Binding Protein Binding
	Biological Process	In Utero Embryonic Development Intracellular Protein Transport Cell Adhesion Chemical Synaptic Transmission Nervous System Development Locomotory Behavior Axo-dendritic Transport Regulation Of Gene Expression Glutamate Secretion Gamma-aminobutyric Acid Secretion Protein Transport Multicellular Organism Growth Establishment Of Localization In Cell Protein-containing Complex Assembly Presynaptic Modulation Of Chemical Synaptic Transmission	Cell Adhesion Cell Recognition
Pathways		Dopamine Neurotransmitter Release Cycle Neurexins and neuroligins Assembly and cell surface presentation of NMDA receptors
Drugs
Diseases
GWAS		Cognitive ability ( 29186694) Cognitive ability (MTAG) ( 29186694) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Extremely high intelligence ( 29520040) Intelligence ( 28530673) Intelligence (MTAG) ( 29326435) Itch intensity from mosquito bite adjusted by bite size ( 28199695) Refractive error ( 32231278)	Iris color (a* coordinate) ( 30895295) Schizophrenia ( 34099189)
Interacting Genes		18 interacting genes: APP ARF3 ARF4 CACNA1B CASK CCS CNTNAP3 CNTNAP4 HTR2C KCNJ12 KIF17 LIN7B NOTCH1 NRXN1 PSEN1 STX1A STXBP1 TJAP1	1 interacting genes: APBA1
Entrez ID		320	79937
HPRD ID		03879	10842
Ensembl ID		ENSG00000107282	ENSG00000106714
Uniprot IDs		Q02410	A6NC89 Q9BZ76
PDB IDs		1AQC 1U37 1U38 1U39 1U3B 1X11 1X45 1Y7N
Enriched GO Terms of Interacting Partners?		Modulation Of Chemical Synaptic Transmission Plasma Membrane Establishment Of Localization In Cell Regulation Of Calcium Ion-dependent Exocytosis Synapse Regulation Of Regulated Secretory Pathway Presynaptic Membrane Positive Regulation Of Synaptic Transmission Positive Regulation Of Calcium Ion-dependent Exocytosis Regulation Of Vesicle-mediated Transport Positive Regulation Of Neurotransmitter Secretion Regulation Of Exocytosis Establishment Of Protein Localization Regulation Of Neurotransmitter Secretion Intracellular Protein Localization Neurotransmitter Transport Positive Regulation Of Excitatory Postsynaptic Potential Protein Transport Calcium-ion Regulated Exocytosis Regulation Of Synaptic Transmission, GABAergic Astrocyte Activation Involved In Immune Response Regulation Of Nervous System Process Cellular Localization Positive Regulation Of Amyloid Fibril Formation Growth Factor Receptor Binding Vesicle-mediated Transport Neurotransmitter Secretion Regulation Of Transport Regulation Of Synapse Organization Intracellular Transport Chemical Synaptic Transmission NMDA Selective Glutamate Receptor Signaling Pathway Cell Adhesion Regulation Of System Process Glutamatergic Synapse Positive Regulation Of Regulated Secretory Pathway Modulation Of Excitatory Postsynaptic Potential Regulation Of Secretion By Cell Trans-synaptic Signaling Signal Release Synaptic Signaling Regulation Of Secretion Response To Amyloid-beta Positive Regulation Of ERK1 And ERK2 Cascade Secretion By Cell Exocytosis Regulation Of Synaptic Vesicle Priming Regulation Of Synaptic Transmission, Glutamatergic SNARE Complex Assembly Regulation Of Amine Transport	Gamma-aminobutyric Acid Transport Nervous System Development Gamma-aminobutyric Acid Secretion Glutamate Secretion XY Body BBAF Complex Tat Protein Binding Brahma Complex Viral RNA Genome Replication Regulation Of Transcription Of Nucleolar Large RRNA By RNA Polymerase I RSC-type Complex Positive Regulation Of Transcription Of Nucleolar Large RRNA By RNA Polymerase I DNA Integration Positive Regulation Of Glucose Mediated Signaling Pathway Hepatocyte Differentiation RNA Polymerase I Core Promoter Sequence-specific DNA Binding NpBAF Complex Germ Cell Nucleus RNA Polymerase I Preinitiation Complex Assembly Regulation Of Glucose Mediated Signaling Pathway Single Stranded Viral RNA Replication Via Double Stranded DNA Intermediate NBAF Complex Host-mediated Activation Of Viral Transcription Nucleosome Disassembly Viral Genome Replication Acid Secretion Presynaptic Active Zone Membrane System Development Regulation Of Nucleotide-excision Repair Nuclear Chromosome Blastocyst Hatching Blastocyst Development Positive Regulation Of Transcription By RNA Polymerase I SWI/SNF Complex Protein-DNA Complex Disassembly Host-mediated Perturbation Of Viral Transcription Regulation Of G0 To G1 Transition Host-mediated Activation Of Viral Process Nucleosomal DNA Binding Presynaptic Modulation Of Chemical Synaptic Transmission Regulation Of Transcription By RNA Polymerase I Protein-containing Complex Assembly Positive Regulation Of Myoblast Differentiation Acidic Amino Acid Transport Positive Regulation Of Stem Cell Population Maintenance Transcription Initiation-coupled Chromatin Remodeling Positive Regulation Of Gene Expression, Epigenetic Protein-containing Complex Organization Transcription Preinitiation Complex Assembly Dicarboxylic Acid Transport
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