PIM2 and HNRNPH3

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		PIM2	HNRNPH3
Gene Name		Pim-2 proto-oncogene, serine/threonine kinase	heterogeneous nuclear ribonucleoprotein H3 (2H9)
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm	Nucleus Nucleoplasm Spliceosomal Complex
	Molecular Function	Protein Serine/threonine Kinase Activity ATP Binding	Nucleotide Binding RNA Binding Protein Binding Poly(A) RNA Binding
	Biological Process	G1/S Transition Of Mitotic Cell Cycle Protein Phosphorylation Male Meiosis Regulation Of Mitotic Cell Cycle Cell Proliferation Negative Regulation Of Cell Proliferation Apoptotic Mitochondrial Changes Response To Virus Positive Regulation Of Autophagy Negative Regulation Of Apoptotic Process Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Positive Regulation Of Transcription, DNA-templated Protein Autophosphorylation Protein Stabilization	MRNA Splicing, Via Spliceosome RNA Processing RNA Splicing Epithelial Cell Differentiation
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		11 interactors: ATXN1 BAD CUTC FBXO18 GSK3B HNRNPH3 IKBKG NDUFB8 RPL21 SOCS1 ZNF821	26 interactors: ANXA11 C14orf1 C17orf85 CCL13 CHERP CRMP1 DDX17 DDX5 EEF1G ERG HNRNPA0 HNRNPA1 HNRNPD HNRNPF HNRNPH1 HNRNPU HNRNPUL1 IL7R KAT5 MAPK6 PIM2 RBM4 RPS4X TTR UTP14A ZMYM2
Entrez ID		11040	3189
HPRD ID		02244	03818
Ensembl ID		ENSG00000102096	ENSG00000096746
Uniprot IDs		Q9P1W9	B4DHY1 P31942 Q53F48
PDB IDs		2IWI
Enriched GO Terms of Interacting Partners?		Regulation Of Phosphorylation Nucleobase-containing Compound Metabolic Process Regulation Of Type B Pancreatic Cell Development Regulation Of Phosphorus Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Regulation Of Intrinsic Apoptotic Signaling Pathway Nitrogen Compound Metabolic Process Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Positive Regulation Of Apoptotic Signaling Pathway Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Fc-epsilon Receptor Signaling Pathway Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Fc Receptor Signaling Pathway Response To Biotic Stimulus Regulation Of Kinase Activity Positive Regulation Of Mitochondrion Organization Positive Regulation Of Intrinsic Apoptotic Signaling Pathway Innate Immune Response Positive Regulation Of Phosphorylation Regulation Of Immune Response Cellular Response To Chromate Cellular Response To Mechanical Stimulus Immune Response-regulating Cell Surface Receptor Signaling Pathway Regulation Of Intracellular Signal Transduction Regulation Of Signal Transduction Negative Regulation Of Phosphorylation Negative Regulation Of Intracellular Signal Transduction Regulation Of Mitochondrion Organization Positive Regulation Of Mitochondrial Membrane Potential Negative Regulation Of Type B Pancreatic Cell Development Suppression By Virus Of Host Apoptotic Process Superior Temporal Gyrus Development Regulation Of Protein Phosphorylation Regulation Of Glucose Metabolic Process Extrinsic Apoptotic Signaling Pathway Negative Regulation Of Signal Transduction Immune Response-regulating Signaling Pathway Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Cellular Protein Metabolic Process Regulation Of Signaling Response To Amino Acid Establishment Of Localization In Cell Nuclear Export Cellular Metabolic Process Re-entry Into Mitotic Cell Cycle Negative Regulation Of Neuron Maturation Negative Regulation Of Signaling Fat Cell Differentiation	RNA Processing RNA Splicing MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions MRNA Metabolic Process MRNA Processing RNA Metabolic Process Gene Expression Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Regulation Of RNA Splicing Posttranscriptional Regulation Of Gene Expression Circadian Regulation Of Translation Regulation Of Gene Expression Positive Regulation Of Intracellular Estrogen Receptor Signaling Pathway Regulation Of MRNA Stability Cellular Metabolic Process Regulation Of RNA Stability Circadian Rhythm Positive Regulation Of Intracellular Steroid Hormone Receptor Signaling Pathway Regulation Of Skeletal Muscle Cell Differentiation Rhythmic Process Regulation Of Intracellular Estrogen Receptor Signaling Pathway Response To External Stimulus MRNA Stabilization Regulation Of Alternative MRNA Splicing, Via Spliceosome Positive Regulation Of Gene Expression Metabolic Process Negative Regulation Of Potassium Ion Export Regulation Of Intracellular Steroid Hormone Receptor Signaling Pathway Regulation Of Nitrogen Compound Metabolic Process Cellular Macromolecule Biosynthetic Process RNA Biosynthetic Process Regulation Of Heart Rate By Hormone Interleukin-7-mediated Signaling Pathway Response To Virus Regulation Of MRNA Splicing, Via Spliceosome Regulation Of Skeletal Muscle Tissue Development Macromolecule Biosynthetic Process Regulation Of Metabolic Process Regulation Of RNA Metabolic Process Regulation Of Translation Positive Regulation Of Translation Signal Transduction By Phosphorylation Cytokinesis, Completion Of Separation Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of MRNA Processing
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Tagcloud (Difference) ?		afrikaans arrival asystole bathing baths bradycardia buckets cape cpr dangers deserves drowned drowning happened incidents inotropes memorial pools pupils resuscitative speaking submersion supervision town unresponsive unwitnessed victim witnessed xhosa
Tagcloud (Intersection) ?