PIM2

Gene Name		Pim-2 proto-oncogene, serine/threonine kinase
Image
Gene Ontology Annotations	Cellular Component	Cytoplasm
	Molecular Function	Protein Serine/threonine Kinase Activity ATP Binding
	Biological Process	G1/S Transition Of Mitotic Cell Cycle Protein Phosphorylation Male Meiosis Regulation Of Mitotic Cell Cycle Cell Proliferation Negative Regulation Of Cell Proliferation Apoptotic Mitochondrial Changes Response To Virus Positive Regulation Of Autophagy Negative Regulation Of Apoptotic Process Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Positive Regulation Of Transcription, DNA-templated Protein Autophosphorylation Protein Stabilization
Pathways
Drugs
Diseases
GWAS
Protein-protein Interactions		11 interactors: ATXN1 BAD CUTC FBXO18 GSK3B HNRNPH3 IKBKG NDUFB8 RPL21 SOCS1 ZNF821
Entrez ID		11040
HPRD ID		02244
Ensembl ID		ENSG00000102096
Uniprot IDs		Q9P1W9
PDB IDs		2IWI
Enriched GO Terms of Interacting Partners?		Regulation Of Phosphorylation Nucleobase-containing Compound Metabolic Process Regulation Of Type B Pancreatic Cell Development Regulation Of Phosphorus Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Regulation Of Intrinsic Apoptotic Signaling Pathway Nitrogen Compound Metabolic Process Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Positive Regulation Of Apoptotic Signaling Pathway Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Fc-epsilon Receptor Signaling Pathway Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Fc Receptor Signaling Pathway Response To Biotic Stimulus Regulation Of Kinase Activity Positive Regulation Of Mitochondrion Organization Positive Regulation Of Intrinsic Apoptotic Signaling Pathway Innate Immune Response Positive Regulation Of Phosphorylation Regulation Of Immune Response Cellular Response To Chromate Cellular Response To Mechanical Stimulus Immune Response-regulating Cell Surface Receptor Signaling Pathway Regulation Of Intracellular Signal Transduction Regulation Of Signal Transduction Negative Regulation Of Phosphorylation Negative Regulation Of Intracellular Signal Transduction Regulation Of Mitochondrion Organization Positive Regulation Of Mitochondrial Membrane Potential Negative Regulation Of Type B Pancreatic Cell Development Suppression By Virus Of Host Apoptotic Process Superior Temporal Gyrus Development Regulation Of Protein Phosphorylation Regulation Of Glucose Metabolic Process Extrinsic Apoptotic Signaling Pathway Negative Regulation Of Signal Transduction Immune Response-regulating Signaling Pathway Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Cellular Protein Metabolic Process Regulation Of Signaling Response To Amino Acid Establishment Of Localization In Cell Nuclear Export Cellular Metabolic Process Re-entry Into Mitotic Cell Cycle Negative Regulation Of Neuron Maturation Negative Regulation Of Signaling Fat Cell Differentiation
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