CEACAM1 and CEACAM8

Number of citations of the paper that reports this interaction (PMID 11994468)
24

Data Source:
HPRD (in vitro)

		CEACAM1	CEACAM8
Gene Name		carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)	carcinoembryonic antigen-related cell adhesion molecule 8
Image
Gene Ontology Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Membrane Integral Component Of Membrane Extracellular Vesicular Exosome	Extracellular Space Plasma Membrane Integral Component Of Plasma Membrane Anchored Component Of Membrane Extracellular Vesicular Exosome
	Molecular Function	Molecular_function Protein Binding Protein Homodimerization Activity
	Biological Process	Angiogenesis Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Integrin-mediated Signaling Pathway Blood Coagulation Cell Migration Leukocyte Migration	Immune Response Blood Coagulation Leukocyte Migration
Pathways		Fibronectin matrix formation Cell surface interactions at the vascular wall	Fibronectin matrix formation Cell surface interactions at the vascular wall
Drugs		Arcitumomab Alpha-D-Mannose
Diseases
GWAS
Protein-Protein Interactions		18 interactors: ADRB2 ANXA2 CARTPT CD209 CEACAM3 CEACAM5 CEACAM6 CEACAM7 CEACAM8 EGFR FLNA INSR MAP3K10 PTPN11 PTPN6 PXN SHC1 SRC	2 interactors: CEACAM1 CEACAM6
Entrez ID		634	1088
HPRD ID		00191	07630
Ensembl ID		ENSG00000079385	ENSG00000124469
Uniprot IDs		P13688 Q3KRG8	B4DLI3 P31997 Q0Z7S6
PDB IDs		2GK2	2DKS
Enriched GO Terms of Interacting Partners?		Activation Of Protein Kinase Activity Positive Regulation Of Intracellular Signal Transduction Regulation Of MAPK Cascade Positive Regulation Of MAPK Cascade Positive Regulation Of Protein Phosphorylation Positive Regulation Of Protein Kinase Activity Regulation Of Protein Phosphorylation Regulation Of Protein Kinase Activity Regulation Of MAP Kinase Activity Positive Regulation Of Kinase Activity Regulation Of Kinase Activity Positive Regulation Of Transferase Activity Positive Regulation Of Phosphorylation Positive Regulation Of Signal Transduction Positive Regulation Of Protein Modification Process Regulation Of Phosphorylation Positive Regulation Of MAP Kinase Activity Regulation Of Phosphorus Metabolic Process Positive Regulation Of Protein Serine/threonine Kinase Activity Positive Regulation Of Cellular Protein Metabolic Process Regulation Of Protein Metabolic Process Positive Regulation Of Protein Metabolic Process Regulation Of Intracellular Signal Transduction Regulation Of Body Fluid Levels Regulation Of Cellular Protein Metabolic Process Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Response To Stress Leukocyte Migration Blood Coagulation Hemostasis Cellular Response To Organonitrogen Compound Peptidyl-tyrosine Phosphorylation Single Organismal Cell-cell Adhesion Regulation Of Catalytic Activity Activation Of MAPK Activity Cellular Response To Peptide Hormone Stimulus Enzyme Linked Receptor Protein Signaling Pathway Cellular Response To Peptide Cellular Response To Hormone Stimulus Epidermal Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Wound Healing Regulation Of Signal Transduction Positive Regulation Of Catalytic Activity Response To Wounding Positive Regulation Of Transport Response To Peptide Hormone Cell Adhesion Regulation Of Signaling Abortive Mitotic Cell Cycle	Leukocyte Migration Blood Coagulation Hemostasis Regulation Of Body Fluid Levels Wound Healing Response To Wounding Cell Migration Cell Motility Locomotion Movement Of Cell Or Subcellular Component Immune System Process Integrin-mediated Signaling Pathway Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Cell-cell Adhesion Via Plasma-membrane Adhesion Molecules Cell-cell Adhesion Response To Stress
Tagcloud ?		4l adhesion carcinoembryonic chemotactic clinicopathologic cxcl density explore extent immunohistochemistry infiltration ln lymph metastasis microarray neutrophil neutrophils node overexpression peritumoral poorer probe qrt squamous tissues tongue tscc upregulate upregulating
Tagcloud (Difference) ?		4l adhesion carcinoembryonic chemotactic clinicopathologic cxcl density explore extent immunohistochemistry infiltration ln lymph metastasis microarray neutrophil neutrophils node overexpression peritumoral poorer probe qrt squamous tissues tongue tscc upregulate upregulating
Tagcloud (Intersection) ?