KCNIP1 and KCND3

Number of citations of the paper that reports this interaction (PubMedID 17187064)
0

Data Source:
BioGRID (pull down)

		KCNIP1	KCND3
Description		potassium voltage-gated channel interacting protein 1	potassium voltage-gated channel subfamily D member 3
Image
GO Annotations	Cellular Component	Cytoplasm Plasma Membrane Voltage-gated Potassium Channel Complex Cytoplasmic Side Of Plasma Membrane Membrane Dendrite Monoatomic Ion Channel Complex Cell Projection Synapse Kv4.3-KChIP1 Channel Complex	Plasma Membrane Voltage-gated Potassium Channel Complex Membrane Dendrite Monoatomic Ion Channel Complex Sarcolemma Cell Projection Neuronal Cell Body Dendritic Spine Postsynaptic Membrane Kv4.3-KChIP1 Channel Complex GABA-ergic Synapse Postsynaptic Specialization Membrane
	Molecular Function	Potassium Channel Activity Calcium Ion Binding Protein Binding Potassium Channel Regulator Activity Transmembrane Transporter Binding Metal Ion Binding	Monoatomic Ion Channel Activity Voltage-gated Potassium Channel Activity A-type (transient Outward) Potassium Channel Activity Potassium Channel Activity Protein Binding Metal Ion Binding Voltage-gated Potassium Channel Activity Involved In Cardiac Muscle Cell Action Potential Repolarization Voltage-gated Potassium Channel Activity Involved In Ventricular Cardiac Muscle Cell Action Potential Repolarization
	Biological Process	Monoatomic Ion Transport Potassium Ion Transport Muscle Contraction Chemical Synaptic Transmission Regulation Of Heart Contraction Regulation Of Signal Transduction Monoatomic Ion Transmembrane Transport Potassium Ion Transmembrane Transport Membrane Repolarization Potassium Ion Export Across Plasma Membrane Regulation Of Potassium Ion Transmembrane Transport	Action Potential Monoatomic Ion Transport Potassium Ion Transport Muscle Contraction Chemical Synaptic Transmission Regulation Of Heart Contraction Monoatomic Ion Transmembrane Transport Protein Homooligomerization Protein Tetramerization Transmembrane Transport Potassium Ion Transmembrane Transport Membrane Repolarization Membrane Repolarization During Cardiac Muscle Cell Action Potential Regulation Of Heart Rate By Cardiac Conduction Potassium Ion Export Across Plasma Membrane Membrane Repolarization During Ventricular Cardiac Muscle Cell Action Potential Ventricular Cardiac Muscle Cell Membrane Repolarization
Pathways		Phase 1 - inactivation of fast Na+ channels	Voltage gated Potassium channels Phase 1 - inactivation of fast Na+ channels
Drugs			Enflurane Disopyramide Imipramine Promethazine Miconazole Nifedipine Dronedarone Vernakalant Dalfampridine Isavuconazole
Diseases
GWAS		Acne (severe) ( 24927181) California verbal learning test score ( 31596458) Liver transplant-free survival in primary sclerosing cholangitis (time to event) ( 28779025) Normalized brain volume ( 19010793) Placental abruption ( 29884306) Pre-treatment viral load in HIV-1 infection ( 31219150) Short-term memory (digit-span task) ( 30741946)	Adult body size ( 32376654) Atrial fibrillation ( 33990960 28416822 29892015 30061737) Early cardiac repolarization ( 22683750 31600170) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Immune reponse to smallpox (secreted IFN-alpha) ( 22610502) Medication use (opioids) ( 31015401) Multisite chronic pain ( 31194737 33830993) P wave duration ( 24850809) P wave terminal force ( 28794112) PR interval ( 30679814 32439900) Response to radiotherapy in cancer (late toxicity) ( 24785509) TPE interval (resting) ( 32386560) Triglyceride levels x SSRI defined daily dose interaction in schizophrenia or bipolar disorder ( 33824429) Visceral adipose tissue adjusted for BMI ( 22589738)
Interacting Genes		16 interacting genes: AMPD3 ASPH CIAO2A DAAM2 IL6ST KCND1 KCND2 KCND3 KCNIP2 LITAF NHLH2 NIF3L1 SOD3 SPP1 SPRED2 TBC1D25	2 interacting genes: KCNIP1 KCNIP2
Entrez ID		30820	3752
HPRD ID		06879	16104
Ensembl ID		ENSG00000182132	ENSG00000171385
Uniprot IDs		Q9NZI2	Q9UK17
PDB IDs		1S1E 2I2R 2NZ0 7E83 7E84 7F3F 7W6N 7W6T	1S1G 2NZ0 7W3Y 7W6N 7W6S 7W6T
Enriched GO Terms of Interacting Partners?		A-type (transient Outward) Potassium Channel Activity Potassium Channel Activity Voltage-gated Potassium Channel Complex Kv4.2-KChIP2 Channel Complex Membrane Repolarization Action Potential Monoatomic Ion Channel Complex Regulation Of System Process Potassium Ion Transmembrane Transport Voltage-gated Potassium Channel Activity Potassium Ion Transport Regulation Of Heart Contraction Muscle Contraction Regulation Of Blood Circulation Muscle System Process Detection Of Calcium Ion Metal Ion Transport Membrane Repolarization During Cardiac Muscle Cell Action Potential Monoatomic Cation Transmembrane Transport Inorganic Cation Transmembrane Transport Membrane Repolarization During Action Potential Neuronal Cell Body Inorganic Ion Transmembrane Transport Dendritic Spine Postsynaptic Specialization Membrane Regulation Of Multicellular Organismal Process Monoatomic Cation Transport Monoatomic Ion Transmembrane Transport Monoatomic Ion Channel Activity Regulation Of Membrane Potential Protein Homooligomerization Dendrite Negative Regulation Of Collateral Sprouting Of Intact Axon In Response To Injury Monoatomic Ion Transport Postsynaptic Membrane Peptidyl-aspartic Acid 3-dioxygenase Activity Interleukin-27 Receptor Activity Leukemia Inhibitory Factor Receptor Activity Regulation Of Glial Cell Differentiation Interleukin-6 Binding Interleukin-6 Receptor Activity Oncostatin-M Receptor Complex Protein Complex Oligomerization Kv4.3-KChIP1 Channel Complex Hypothalamus Gonadotrophin-releasing Hormone Neuron Development Positive Regulation Of Estradiol Secretion Cytoplasmic Side Of Late Endosome Membrane Metal Ion Binding AMP Deaminase Activity Regulation Of Inositol 1,4,5-trisphosphate-sensitive Calcium-release Channel Activity	Membrane Repolarization Potassium Channel Regulator Activity Regulation Of Potassium Ion Transmembrane Transport Potassium Channel Activity Regulation Of Potassium Ion Transport Voltage-gated Potassium Channel Complex Monoatomic Ion Channel Complex Transmembrane Transporter Binding Potassium Ion Transmembrane Transport Potassium Ion Transport Regulation Of Heart Contraction Muscle Contraction Regulation Of Blood Circulation Muscle System Process Kv4.2-KChIP2 Channel Complex Regulation Of Monoatomic Cation Transmembrane Transport Kv4.3-KChIP1 Channel Complex Regulation Of Monoatomic Ion Transmembrane Transport Chemical Synaptic Transmission Regulation Of Metal Ion Transport Trans-synaptic Signaling Synaptic Signaling Positive Regulation Of Potassium Ion Export Across Plasma Membrane Clustering Of Voltage-gated Potassium Channels A-type (transient Outward) Potassium Channel Activity ER Retention Sequence Binding Regulation Of Monoatomic Ion Transport Regulation Of Membrane Potential Dendrite Regulation Of System Process Cell-cell Signaling Monoatomic Cation Transmembrane Transport Metal Ion Transport Inorganic Cation Transmembrane Transport Neuronal Ion Channel Clustering Calcium Ion Binding Signaling Regulation Of Potassium Ion Export Across Plasma Membrane Cell Communication Inorganic Ion Transmembrane Transport Detection Of Calcium Ion Potassium Ion Export Across Plasma Membrane Monoatomic Cation Transport Monoatomic Ion Transmembrane Transport Membrane Repolarization During Cardiac Muscle Cell Action Potential Membrane Repolarization During Action Potential Monoatomic Ion Transport Synapse Positive Regulation Of Potassium Ion Transmembrane Transport Positive Regulation Of Potassium Ion Transport
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?