KCNIP1 and KCNIP2

Number of citations of the paper that reports this interaction (PubMedID 33961781)
97

Data Source:
BioGRID (affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down)

		KCNIP1	KCNIP2
Description		potassium voltage-gated channel interacting protein 1	potassium voltage-gated channel interacting protein 2
Image
GO Annotations	Cellular Component	Cytoplasm Plasma Membrane Voltage-gated Potassium Channel Complex Cytoplasmic Side Of Plasma Membrane Membrane Dendrite Monoatomic Ion Channel Complex Cell Projection Synapse Kv4.3-KChIP1 Channel Complex	Cytoplasm Plasma Membrane Voltage-gated Potassium Channel Complex Membrane Dendrite Monoatomic Ion Channel Complex Synapse Kv4.2-KChIP2 Channel Complex
	Molecular Function	Potassium Channel Activity Calcium Ion Binding Protein Binding Potassium Channel Regulator Activity Transmembrane Transporter Binding Metal Ion Binding	A-type (transient Outward) Potassium Channel Activity Potassium Channel Activity Calcium Ion Binding Protein Binding Potassium Channel Regulator Activity Identical Protein Binding Transmembrane Transporter Binding Protein-containing Complex Binding Metal Ion Binding ER Retention Sequence Binding
	Biological Process	Monoatomic Ion Transport Potassium Ion Transport Muscle Contraction Chemical Synaptic Transmission Regulation Of Heart Contraction Regulation Of Signal Transduction Monoatomic Ion Transmembrane Transport Potassium Ion Transmembrane Transport Membrane Repolarization Potassium Ion Export Across Plasma Membrane Regulation Of Potassium Ion Transmembrane Transport	Action Potential Detection Of Calcium Ion Monoatomic Ion Transport Potassium Ion Transport Muscle Contraction Signal Transduction Chemical Synaptic Transmission Regulation Of Heart Contraction Regulation Of Signal Transduction Monoatomic Ion Transmembrane Transport Clustering Of Voltage-gated Potassium Channels Regulation Of Membrane Repolarization Potassium Ion Transmembrane Transport Membrane Repolarization Membrane Repolarization During Cardiac Muscle Cell Action Potential Regulation Of Potassium Ion Transmembrane Transport Regulation Of Potassium Ion Export Across Plasma Membrane Positive Regulation Of Potassium Ion Export Across Plasma Membrane
Pathways		Phase 1 - inactivation of fast Na+ channels	Phase 1 - inactivation of fast Na+ channels
Drugs
Diseases
GWAS		Acne (severe) ( 24927181) California verbal learning test score ( 31596458) Liver transplant-free survival in primary sclerosing cholangitis (time to event) ( 28779025) Normalized brain volume ( 19010793) Placental abruption ( 29884306) Pre-treatment viral load in HIV-1 infection ( 31219150) Short-term memory (digit-span task) ( 30741946)	Raw vegetable consumption ( 32066663)
Interacting Genes		16 interacting genes: AMPD3 ASPH CIAO2A DAAM2 IL6ST KCND1 KCND2 KCND3 KCNIP2 LITAF NHLH2 NIF3L1 SOD3 SPP1 SPRED2 TBC1D25	5 interacting genes: GOLGA7 KCND2 KCND3 KCNIP1 SYCE1L
Entrez ID		30820	30819
HPRD ID		06879	06880
Ensembl ID		ENSG00000182132	ENSG00000120049
Uniprot IDs		Q9NZI2	A0A2R8Y6D7 B3KSZ5 Q9NS61
PDB IDs		1S1E 2I2R 2NZ0 7E83 7E84 7F3F 7W6N 7W6T	7UKH 7W6S
Enriched GO Terms of Interacting Partners?		A-type (transient Outward) Potassium Channel Activity Potassium Channel Activity Voltage-gated Potassium Channel Complex Kv4.2-KChIP2 Channel Complex Membrane Repolarization Action Potential Monoatomic Ion Channel Complex Regulation Of System Process Potassium Ion Transmembrane Transport Voltage-gated Potassium Channel Activity Potassium Ion Transport Regulation Of Heart Contraction Muscle Contraction Regulation Of Blood Circulation Muscle System Process Detection Of Calcium Ion Metal Ion Transport Membrane Repolarization During Cardiac Muscle Cell Action Potential Monoatomic Cation Transmembrane Transport Inorganic Cation Transmembrane Transport Membrane Repolarization During Action Potential Neuronal Cell Body Inorganic Ion Transmembrane Transport Dendritic Spine Postsynaptic Specialization Membrane Regulation Of Multicellular Organismal Process Monoatomic Cation Transport Monoatomic Ion Transmembrane Transport Monoatomic Ion Channel Activity Regulation Of Membrane Potential Protein Homooligomerization Dendrite Negative Regulation Of Collateral Sprouting Of Intact Axon In Response To Injury Monoatomic Ion Transport Postsynaptic Membrane Peptidyl-aspartic Acid 3-dioxygenase Activity Interleukin-27 Receptor Activity Leukemia Inhibitory Factor Receptor Activity Regulation Of Glial Cell Differentiation Interleukin-6 Binding Interleukin-6 Receptor Activity Oncostatin-M Receptor Complex Protein Complex Oligomerization Kv4.3-KChIP1 Channel Complex Hypothalamus Gonadotrophin-releasing Hormone Neuron Development Positive Regulation Of Estradiol Secretion Cytoplasmic Side Of Late Endosome Membrane Metal Ion Binding AMP Deaminase Activity Regulation Of Inositol 1,4,5-trisphosphate-sensitive Calcium-release Channel Activity	Membrane Repolarization Kv4.3-KChIP1 Channel Complex A-type (transient Outward) Potassium Channel Activity Potassium Channel Activity Voltage-gated Potassium Channel Complex Monoatomic Ion Channel Complex Potassium Ion Transmembrane Transport Potassium Ion Export Across Plasma Membrane Potassium Ion Transport Regulation Of Heart Contraction Muscle Contraction Regulation Of Blood Circulation Muscle System Process Postsynaptic Specialization Membrane Chemical Synaptic Transmission Trans-synaptic Signaling Synaptic Signaling Voltage-gated Potassium Channel Activity Export Across Plasma Membrane Regulation Of Membrane Potential Dendrite Regulation Of System Process GABA-ergic Synapse Cell-cell Signaling Action Potential Metal Ion Transport Inorganic Cation Transmembrane Transport Monoatomic Cation Transmembrane Transport Signaling Cell Communication Kv4.2-KChIP2 Channel Complex Inorganic Ion Transmembrane Transport Dendritic Spine Monoatomic Cation Transport Monoatomic Ion Transmembrane Transport Voltage-gated Monoatomic Ion Channel Activity Involved In Regulation Of Postsynaptic Membrane Potential Palmitoyltransferase Complex Monoatomic Ion Channel Activity Voltage-gated Potassium Channel Activity Involved In Cardiac Muscle Cell Action Potential Repolarization Protein Homooligomerization Monoatomic Ion Transport Postsynaptic Membrane Protein Complex Oligomerization Regulation Of Biological Quality Transmembrane Transport Peptidyl-L-cysteine S-palmitoylation Locomotor Rhythm Cell Projection Voltage-gated Potassium Channel Activity Involved In Ventricular Cardiac Muscle Cell Action Potential Repolarization Ventricular Cardiac Muscle Cell Membrane Repolarization
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?