KCND3 and KCNIP2

Number of citations of the paper that reports this interaction (PMID 12928444)
8

Data Source:
BioGRID (affinity chromatography technology)
HPRD (in vivo)

		KCND3	KCNIP2
Gene Name		potassium channel, voltage gated Shal related subfamily D, member 3	Kv channel interacting protein 2
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Plasma Membrane Voltage-gated Potassium Channel Complex Dendrite Sarcolemma Neuronal Cell Body Perinuclear Endoplasmic Reticulum	Cytoplasm Voltage-gated Potassium Channel Complex
	Molecular Function	A-type (transient Outward) Potassium Channel Activity Delayed Rectifier Potassium Channel Activity Protein Binding Ion Channel Binding Metal Ion Binding	A-type (transient Outward) Potassium Channel Activity Calcium Ion Binding Protein Binding Potassium Channel Regulator Activity Identical Protein Binding Ion Channel Binding ER Retention Sequence Binding Protein N-terminus Binding
	Biological Process	Potassium Ion Transport Synaptic Transmission Regulation Of Ion Transmembrane Transport Protein Homooligomerization Potassium Ion Export Membrane Repolarization	Detection Of Calcium Ion Potassium Ion Transport Muscle Contraction Signal Transduction Synaptic Transmission Regulation Of Heart Contraction Clustering Of Voltage-gated Potassium Channels Potassium Ion Export Potassium Ion Transmembrane Transport Membrane Repolarization Regulation Of Cation Channel Activity
Pathways		Potassium Channels Voltage gated Potassium channels
Drugs
Diseases
GWAS		Cardiac repolarization ( 22683750) Immune reponse to smallpox (secreted IFN-alpha) ( 22610502) Visceral adipose tissue adjusted for BMI ( 22589738)
Protein-Protein Interactions		1 interactors: KCNIP2	3 interactors: KCND2 KCND3 KCNIP1
Entrez ID		3752	30819
HPRD ID		16104	06880
Ensembl ID		ENSG00000171385	ENSG00000120049
Uniprot IDs		Q9UK17	B3KSZ5 Q3YAC7 Q9NS61
PDB IDs		1S1G 2NZ0
Enriched GO Terms of Interacting Partners?		Clustering Of Voltage-gated Potassium Channels Potassium Ion Export Neuronal Ion Channel Clustering Detection Of Calcium Ion Membrane Repolarization Neuron Maturation Regulation Of Cation Channel Activity Response To Calcium Ion Regulation Of Ion Transmembrane Transporter Activity Regulation Of Transmembrane Transporter Activity Cell Maturation Regulation Of Heart Contraction Potassium Ion Transmembrane Transport Potassium Ion Transport Muscle Contraction Muscle System Process Regulation Of Membrane Potential Response To Metal Ion	Potassium Ion Transmembrane Transport Potassium Ion Transport Regulation Of Ion Transmembrane Transport Synaptic Transmission Regulation Of Ion Transport Monovalent Inorganic Cation Transport Metal Ion Transport Cell-cell Signaling Cation Transmembrane Transport Cation Transport Ion Transmembrane Transport Protein Homooligomerization Regulation Of Membrane Potential Transmembrane Transport Ion Transport Protein Oligomerization Positive Regulation Of Action Potential Potassium Ion Export Detection Of Calcium Ion Membrane Repolarization Protein Complex Assembly Transport Action Potential Signaling Cell Communication Response To Calcium Ion Cellular Component Assembly Response To Metal Ion
Tagcloud ?			ablate addressed apd arrhythmias arrhythmogenesis augmented beats caffeine cardiomyocytes cofactors establishment h3k4me h3k4me3 harbinger heritable inducibly initiating interacting isoproterenol kv marks methyltransferases pax premature ptip repolarization upstroke velocity ventricular
Tagcloud (Difference) ?			ablate addressed apd arrhythmias arrhythmogenesis augmented beats caffeine cardiomyocytes cofactors establishment h3k4me h3k4me3 harbinger heritable inducibly initiating interacting isoproterenol kv marks methyltransferases pax premature ptip repolarization upstroke velocity ventricular
Tagcloud (Intersection) ?