KCNIP2 and KCND2

Number of citations of the paper that reports this interaction (PubMedID 11287421)
0

Data Source:
HPRD (in vitro)

		KCNIP2	KCND2
Description		potassium voltage-gated channel interacting protein 2	potassium voltage-gated channel subfamily D member 2
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GO Annotations	Cellular Component	Cytoplasm Plasma Membrane Voltage-gated Potassium Channel Complex Membrane Dendrite Monoatomic Ion Channel Complex Synapse Kv4.2-KChIP2 Channel Complex	Plasma Membrane Voltage-gated Potassium Channel Complex Membrane Dendrite Neuronal Cell Body Membrane Monoatomic Ion Channel Complex Cell Projection Neuronal Cell Body Dendritic Spine Perikaryon Plasma Membrane Raft Synapse Postsynaptic Membrane Anchoring Junction Kv4.2-KChIP2 Channel Complex Glutamatergic Synapse GABA-ergic Synapse Postsynaptic Specialization Membrane
	Molecular Function	A-type (transient Outward) Potassium Channel Activity Potassium Channel Activity Calcium Ion Binding Protein Binding Potassium Channel Regulator Activity Identical Protein Binding Transmembrane Transporter Binding Protein-containing Complex Binding Metal Ion Binding ER Retention Sequence Binding	Monoatomic Ion Channel Activity Voltage-gated Potassium Channel Activity A-type (transient Outward) Potassium Channel Activity Potassium Channel Activity Protein Binding Metal Ion Binding Voltage-gated Monoatomic Ion Channel Activity Involved In Regulation Of Postsynaptic Membrane Potential
	Biological Process	Action Potential Detection Of Calcium Ion Monoatomic Ion Transport Potassium Ion Transport Muscle Contraction Signal Transduction Chemical Synaptic Transmission Regulation Of Heart Contraction Regulation Of Signal Transduction Monoatomic Ion Transmembrane Transport Clustering Of Voltage-gated Potassium Channels Regulation Of Membrane Repolarization Potassium Ion Transmembrane Transport Membrane Repolarization Membrane Repolarization During Cardiac Muscle Cell Action Potential Regulation Of Potassium Ion Transmembrane Transport Regulation Of Potassium Ion Export Across Plasma Membrane Positive Regulation Of Potassium Ion Export Across Plasma Membrane	Action Potential Monoatomic Ion Transport Potassium Ion Transport Muscle Contraction Chemical Synaptic Transmission Regulation Of Heart Contraction Neuronal Action Potential Sensory Perception Of Pain Monoatomic Ion Transmembrane Transport Locomotor Rhythm Protein Homooligomerization Transmembrane Transport Regulation Of Postsynaptic Membrane Potential Cellular Response To Hypoxia Potassium Ion Transmembrane Transport Membrane Repolarization
Pathways		Phase 1 - inactivation of fast Na+ channels	Voltage gated Potassium channels Phase 1 - inactivation of fast Na+ channels
Drugs			Enflurane Disopyramide Imipramine Promethazine Miconazole Dalfampridine
Diseases
GWAS		Raw vegetable consumption ( 32066663)	Age-related cognitive decline (language) (slope of z-scores) ( 30954325) Alcohol and nicotine co-dependence ( 22488850) Heel bone mineral density ( 30598549) Immune reponse to smallpox (secreted IL-12p40) ( 22610502) Maximum stenosis ( 32469969) Mean degree of stenosis ( 32469969)
Interacting Genes		5 interacting genes: GOLGA7 KCND2 KCND3 KCNIP1 SYCE1L	8 interacting genes: DLG4 DPP10 FLNC IL16 KCNIP1 KCNIP2 KCNIP4 NCS1
Entrez ID		30819	3751
HPRD ID		06880	09254
Ensembl ID		ENSG00000120049	ENSG00000184408
Uniprot IDs		A0A2R8Y6D7 B3KSZ5 Q9NS61	A4D0V9 Q9NZV8
PDB IDs		7UKH 7W6S	7E7Z 7E83 7E84 7E87 7E8B 7E8E 7E8H 7F0J 7F3F 7UK5 7UKC 7UKD 7UKE 7UKF 7UKG 7UKH
Enriched GO Terms of Interacting Partners?		Membrane Repolarization Kv4.3-KChIP1 Channel Complex A-type (transient Outward) Potassium Channel Activity Potassium Channel Activity Voltage-gated Potassium Channel Complex Monoatomic Ion Channel Complex Potassium Ion Transmembrane Transport Potassium Ion Export Across Plasma Membrane Potassium Ion Transport Regulation Of Heart Contraction Muscle Contraction Regulation Of Blood Circulation Muscle System Process Postsynaptic Specialization Membrane Chemical Synaptic Transmission Trans-synaptic Signaling Synaptic Signaling Voltage-gated Potassium Channel Activity Export Across Plasma Membrane Regulation Of Membrane Potential Dendrite Regulation Of System Process GABA-ergic Synapse Cell-cell Signaling Action Potential Metal Ion Transport Inorganic Cation Transmembrane Transport Monoatomic Cation Transmembrane Transport Signaling Cell Communication Kv4.2-KChIP2 Channel Complex Inorganic Ion Transmembrane Transport Dendritic Spine Monoatomic Cation Transport Monoatomic Ion Transmembrane Transport Voltage-gated Monoatomic Ion Channel Activity Involved In Regulation Of Postsynaptic Membrane Potential Palmitoyltransferase Complex Monoatomic Ion Channel Activity Voltage-gated Potassium Channel Activity Involved In Cardiac Muscle Cell Action Potential Repolarization Protein Homooligomerization Monoatomic Ion Transport Postsynaptic Membrane Protein Complex Oligomerization Regulation Of Biological Quality Transmembrane Transport Peptidyl-L-cysteine S-palmitoylation Locomotor Rhythm Cell Projection Voltage-gated Potassium Channel Activity Involved In Ventricular Cardiac Muscle Cell Action Potential Repolarization Ventricular Cardiac Muscle Cell Membrane Repolarization	Voltage-gated Potassium Channel Complex Potassium Channel Regulator Activity Regulation Of Potassium Ion Transmembrane Transport Regulation Of Potassium Ion Transport Regulation Of Metal Ion Transport Regulation Of Monoatomic Ion Transport Plasma Membrane Regulation Of Monoatomic Cation Transmembrane Transport Potassium Channel Activity Regulation Of Monoatomic Ion Transmembrane Transport Monoatomic Ion Channel Complex Regulation Of Transport Transmembrane Transporter Binding Regulation Of Membrane Potential Potassium Ion Transmembrane Transport Dendrite Potassium Ion Transport Membrane Repolarization Metal Ion Transport Protein Localization To Cell Periphery Monoatomic Cation Transmembrane Transport Inorganic Cation Transmembrane Transport Calcium Ion Binding Inorganic Ion Transmembrane Transport Monoatomic Cation Transport Monoatomic Ion Transmembrane Transport Chemical Synaptic Transmission Protein Localization To Membrane P2Y1 Nucleotide Receptor Binding Hepatocyte Growth Factor Receptor Activity Trans-synaptic Signaling Synaptic Signaling Monoatomic Ion Transport Synapse Protein Phosphatase Binding Kv4.2-KChIP2 Channel Complex Kv4.3-KChIP1 Channel Complex Regulation Of Signal Transduction Beta-1 Adrenergic Receptor Binding Regulation Of Grooming Behavior Positive Regulation Of Neutrophil Activation Transmembrane Transport Localization Within Membrane Positive Regulation Of Potassium Ion Export Across Plasma Membrane Clustering Of Voltage-gated Potassium Channels A-type (transient Outward) Potassium Channel Activity AMPA Glutamate Receptor Clustering Regulation Of System Process Neuroligin Family Protein Binding Positive Regulation Of Chemotaxis
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