KCNIP2 and KCND2

Number of citations of the paper that reports this interaction (PMID 11287421)
55

Data Source:
HPRD (in vitro)

		KCNIP2	KCND2
Gene Name		Kv channel interacting protein 2	potassium channel, voltage gated Shal related subfamily D, member 2
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Voltage-gated Potassium Channel Complex	Plasma Membrane Voltage-gated Potassium Channel Complex Integral Component Of Membrane Intrinsic Component Of Plasma Membrane Dendritic Spine
	Molecular Function	A-type (transient Outward) Potassium Channel Activity Calcium Ion Binding Protein Binding Potassium Channel Regulator Activity Identical Protein Binding Ion Channel Binding ER Retention Sequence Binding Protein N-terminus Binding	Voltage-gated Potassium Channel Activity A-type (transient Outward) Potassium Channel Activity Delayed Rectifier Potassium Channel Activity Protein Binding Metal Ion Binding
	Biological Process	Detection Of Calcium Ion Potassium Ion Transport Muscle Contraction Signal Transduction Synaptic Transmission Regulation Of Heart Contraction Clustering Of Voltage-gated Potassium Channels Potassium Ion Export Potassium Ion Transmembrane Transport Membrane Repolarization Regulation Of Cation Channel Activity	Action Potential Synaptic Transmission Regulation Of Ion Transmembrane Transport Protein Homooligomerization Potassium Ion Transmembrane Transport
Pathways			Potassium Channels Voltage gated Potassium channels
Drugs
Diseases
GWAS			Alcohol and nictotine co-dependence ( 22488850) Immune reponse to smallpox (secreted IL-12p40) ( 22610502)
Protein-Protein Interactions		3 interactors: KCND2 KCND3 KCNIP1	8 interactors: DLG4 DPP10 FLNC IL16 KCNIP1 KCNIP2 KCNIP4 NCS1
Entrez ID		30819	3751
HPRD ID		06880	09254
Ensembl ID		ENSG00000120049	ENSG00000184408
Uniprot IDs		B3KSZ5 Q3YAC7 Q9NS61	A4D0V9 Q75LS7 Q9NZV8
PDB IDs
Enriched GO Terms of Interacting Partners?		Potassium Ion Transmembrane Transport Potassium Ion Transport Regulation Of Ion Transmembrane Transport Synaptic Transmission Regulation Of Ion Transport Monovalent Inorganic Cation Transport Metal Ion Transport Cell-cell Signaling Cation Transmembrane Transport Cation Transport Ion Transmembrane Transport Protein Homooligomerization Regulation Of Membrane Potential Transmembrane Transport Ion Transport Protein Oligomerization Positive Regulation Of Action Potential Potassium Ion Export Detection Of Calcium Ion Membrane Repolarization Protein Complex Assembly Transport Action Potential Signaling Cell Communication Response To Calcium Ion Cellular Component Assembly Response To Metal Ion	Regulation Of Ion Transmembrane Transport Regulation Of Ion Transport Detection Of Calcium Ion Potassium Ion Transmembrane Transport Potassium Ion Transport Metal Ion Transport Cation Transmembrane Transport Cation Transport Ion Transmembrane Transport Response To Calcium Ion Synaptic Transmission Regulation Of Ion Transmembrane Transporter Activity Clustering Of Voltage-gated Potassium Channels Regulation Of Transmembrane Transporter Activity Monovalent Inorganic Cation Transport Transmembrane Transport Regulation Of Behavior Ion Transport Alpha-amino-3-hydroxy-5-methyl-4-isoxazole Propionate Selective Glutamate Receptor Clustering Regulation Of Grooming Behavior Maintenance Of Apical/basal Cell Polarity Receptor Localization To Synapse Cell-cell Signaling Negative Regulation Of Receptor Internalization Positive Regulation Of Action Potential Locomotory Exploration Behavior Regulation Of Membrane Potential Potassium Ion Export Dendritic Spine Morphogenesis Neuronal Ion Channel Clustering Maintenance Of Cell Polarity Synaptic Vesicle Maturation Membrane Repolarization Vocalization Behavior Response To Metal Ion Induction Of Positive Chemotaxis Dendritic Spine Development Protein Localization To Synapse Negative Regulation Of Receptor-mediated Endocytosis Regulation Of Vesicle-mediated Transport Dendritic Spine Organization Regulation Of N-methyl-D-aspartate Selective Glutamate Receptor Activity Detection Of Chemical Stimulus Cortical Actin Cytoskeleton Organization Exploration Behavior Postsynaptic Membrane Organization Establishment Or Maintenance Of Apical/basal Cell Polarity Cortical Cytoskeleton Organization Regulation Of Long-term Neuronal Synaptic Plasticity Regulation Of Receptor Internalization
Tagcloud ?		ablate addressed apd arrhythmias arrhythmogenesis augmented beats caffeine cardiomyocytes cofactors establishment h3k4me h3k4me3 harbinger heritable inducibly initiating interacting isoproterenol kv marks methyltransferases pax premature ptip repolarization upstroke velocity ventricular	channel classes custom excitability gated genotyping gmm haplotype intriguing inwardly kcna1 kcnj3 kcnj6 kcnk9 latent member membership mild monthly pain persistent postsurgical potassium rectifying snps subfamily variations voltage warrant
Tagcloud (Difference) ?		ablate addressed apd arrhythmias arrhythmogenesis augmented beats caffeine cardiomyocytes cofactors establishment h3k4me h3k4me3 harbinger heritable inducibly initiating interacting isoproterenol kv marks methyltransferases pax premature ptip repolarization upstroke velocity ventricular	channel classes custom excitability gated genotyping gmm haplotype intriguing inwardly kcna1 kcnj3 kcnj6 kcnk9 latent member membership mild monthly pain persistent postsurgical potassium rectifying snps subfamily variations voltage warrant
Tagcloud (Intersection) ?