KCNIP2 and KCND3

Number of citations of the paper that reports this interaction (PMID 12928444)
8

Data Source:
BioGRID (affinity chromatography technology)
HPRD (in vivo)

		KCNIP2	KCND3
Gene Name		Kv channel interacting protein 2	potassium channel, voltage gated Shal related subfamily D, member 3
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Voltage-gated Potassium Channel Complex	Plasma Membrane Voltage-gated Potassium Channel Complex Dendrite Sarcolemma Neuronal Cell Body Perinuclear Endoplasmic Reticulum
	Molecular Function	A-type (transient Outward) Potassium Channel Activity Calcium Ion Binding Protein Binding Potassium Channel Regulator Activity Identical Protein Binding Ion Channel Binding ER Retention Sequence Binding Protein N-terminus Binding	A-type (transient Outward) Potassium Channel Activity Delayed Rectifier Potassium Channel Activity Protein Binding Ion Channel Binding Metal Ion Binding
	Biological Process	Detection Of Calcium Ion Potassium Ion Transport Muscle Contraction Signal Transduction Synaptic Transmission Regulation Of Heart Contraction Clustering Of Voltage-gated Potassium Channels Potassium Ion Export Potassium Ion Transmembrane Transport Membrane Repolarization Regulation Of Cation Channel Activity	Potassium Ion Transport Synaptic Transmission Regulation Of Ion Transmembrane Transport Protein Homooligomerization Potassium Ion Export Membrane Repolarization
Pathways			Potassium Channels Voltage gated Potassium channels
Drugs
Diseases
GWAS			Cardiac repolarization ( 22683750) Immune reponse to smallpox (secreted IFN-alpha) ( 22610502) Visceral adipose tissue adjusted for BMI ( 22589738)
Protein-Protein Interactions		3 interactors: KCND2 KCND3 KCNIP1	1 interactors: KCNIP2
Entrez ID		30819	3752
HPRD ID		06880	16104
Ensembl ID		ENSG00000120049	ENSG00000171385
Uniprot IDs		B3KSZ5 Q3YAC7 Q9NS61	Q9UK17
PDB IDs			1S1G 2NZ0
Enriched GO Terms of Interacting Partners?		Potassium Ion Transmembrane Transport Potassium Ion Transport Regulation Of Ion Transmembrane Transport Synaptic Transmission Regulation Of Ion Transport Monovalent Inorganic Cation Transport Metal Ion Transport Cell-cell Signaling Cation Transmembrane Transport Cation Transport Ion Transmembrane Transport Protein Homooligomerization Regulation Of Membrane Potential Transmembrane Transport Ion Transport Protein Oligomerization Positive Regulation Of Action Potential Potassium Ion Export Detection Of Calcium Ion Membrane Repolarization Protein Complex Assembly Transport Action Potential Signaling Cell Communication Response To Calcium Ion Cellular Component Assembly Response To Metal Ion	Clustering Of Voltage-gated Potassium Channels Potassium Ion Export Neuronal Ion Channel Clustering Detection Of Calcium Ion Membrane Repolarization Neuron Maturation Regulation Of Cation Channel Activity Response To Calcium Ion Regulation Of Ion Transmembrane Transporter Activity Regulation Of Transmembrane Transporter Activity Cell Maturation Regulation Of Heart Contraction Potassium Ion Transmembrane Transport Potassium Ion Transport Muscle Contraction Muscle System Process Regulation Of Membrane Potential Response To Metal Ion
Tagcloud ?		ablate addressed apd arrhythmias arrhythmogenesis augmented beats caffeine cardiomyocytes cofactors establishment h3k4me h3k4me3 harbinger heritable inducibly initiating interacting isoproterenol kv marks methyltransferases pax premature ptip repolarization upstroke velocity ventricular
Tagcloud (Difference) ?		ablate addressed apd arrhythmias arrhythmogenesis augmented beats caffeine cardiomyocytes cofactors establishment h3k4me h3k4me3 harbinger heritable inducibly initiating interacting isoproterenol kv marks methyltransferases pax premature ptip repolarization upstroke velocity ventricular
Tagcloud (Intersection) ?