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TNPO2 and RAN
Number of citations of the paper that reports this interaction (PMID
12384575
)
7
Data Source:
BioGRID
(genetic interference, pull down)
TNPO2
RAN
Gene Name
transportin 2
RAN, member RAS oncogene family
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleus
Cytoplasm
Chromatin
Nucleus
Nuclear Pore
Nucleoplasm
Cytoplasm
Cytosol
Membrane
Melanosome
Recycling Endosome
Extracellular Vesicular Exosome
Molecular Function
Protein Binding
Nuclear Localization Sequence Binding
Ran GTPase Binding
Chromatin Binding
Transcription Coactivator Activity
GTPase Activity
Protein Binding
GTP Binding
GDP Binding
Protein Domain Specific Binding
Poly(A) RNA Binding
Androgen Receptor Binding
Biological Process
Intracellular Protein Transport
Ribosomal Large Subunit Export From Nucleus
Ribosomal Small Subunit Export From Nucleus
DNA Metabolic Process
Protein Import Into Nucleus
Protein Export From Nucleus
Mitotic Spindle Organization
Mitotic Nuclear Division
Signal Transduction
Small GTPase Mediated Signal Transduction
Spermatid Development
Gene Expression
Viral Process
Viral Life Cycle
Actin Cytoskeleton Organization
Androgen Receptor Signaling Pathway
Positive Regulation Of Protein Binding
Cellular Protein Complex Localization
Small Molecule Metabolic Process
Positive Regulation Of Transcription, DNA-templated
Cell Division
Intracellular Transport Of Virus
Pathways
Transcriptional regulation by small RNAs
Metabolism of lipids and lipoproteins
Nuclear import of Rev protein
HIV Infection
Regulatory RNA pathways
Rev-mediated nuclear export of HIV RNA
Host Interactions of HIV factors
MicroRNA (miRNA) biogenesis
Influenza Infection
Interactions of Rev with host cellular proteins
Late Phase of HIV Life Cycle
Influenza Life Cycle
Regulation of cholesterol biosynthesis by SREBP (SREBF)
Export of Viral Ribonucleoproteins from Nucleus
HIV Life Cycle
Rev-mediated nuclear export of HIV RNA
NEP/NS2 Interacts with the Cellular Export Machinery
Drugs
Diseases
GWAS
Protein-Protein Interactions
16 interactors:
A1CF
APIP
C1orf94
CAMK2D
CRYAB
ELAVL1
EXOC5
KLHL2
NME1
NUP98
NXF1
PIK3CD
PNMA5
RAN
TCL1B
TERF1
55 interactors:
ABL1
ADRB2
AR
ASAP2
BCAR1
BMPR1B
CSE1L
EP300
GADD45G
GIT1
IPO11
IPO13
IPO5
IPO7
KIAA1377
KPNA2
KPNB1
MBP
MSL1
NEK9
NR3C1
NSMF
NUP153
NUP50
NUPR1
NUTF2
NXF1
NXT1
PAK4
PTMA
RANBP1
RANBP10
RANBP2
RANBP3
RANBP9
RANGAP1
RANGRF
RCC1
RGPD5
RPL7
SMAD1
SMAD2
SMARCB1
SMURF2
SNUPN
SPAG8
SSRP1
TGFBR1
TNPO1
TNPO2
XPO1
XPO4
XPO5
XPO7
XPOT
Entrez ID
30000
5901
HPRD ID
04301
03109
Ensembl ID
ENSG00000105576
Uniprot IDs
O14787
Q05D48
Q4LE60
B4DV51
P62826
PDB IDs
1I2M
1IBR
1K5D
1K5G
1QBK
1RRP
3CH5
3EA5
3GJ0
3GJ3
3GJ4
3GJ5
3GJ6
3GJ7
3GJ8
3GJX
3NBY
3NBZ
3NC0
3NC1
3ZJY
4GMX
4GPT
4HAT
4HAU
4HAV
4HAW
4HAX
4HAY
4HAZ
4HB0
4HB2
4HB3
4HB4
Enriched GO Terms of Interacting Partners
?
RNA Localization
Nucleocytoplasmic Transport
Nuclear Transport
Regulation Of Apoptotic Process
Protein Import Into Nucleus, Docking
Negative Regulation Of Telomere Maintenance Via Semi-conservative Replication
Cytidine To Uridine Editing
L-methionine Biosynthetic Process From S-adenosylmethionine
Intracellular Transport
Regulation Of Cell Death
Cellular Localization
Ribosomal Small Subunit Export From Nucleus
Regulation Of Cardiac Muscle Cell Action Potential Involved In Regulation Of Contraction
Cardiac Muscle Cell Contraction
Natural Killer Cell Chemotaxis
B Cell Chemotaxis
Mast Cell Differentiation
Telomeric Loop Formation
Age-dependent Telomere Shortening
Protein Oligomerization
MRNA Transport
Nuclear Export
Protein Import Into Nucleus
Positive Regulation Of Binding
Neutrophil Extravasation
Telomere Maintenance Via Telomere Shortening
Mast Cell Chemotaxis
Regulation Of Generation Of L-type Calcium Current
Protein Complex Assembly
Nuclear Import
DNA Metabolic Process
RNA Transport
Positive Regulation Of Rac Protein Signal Transduction
Respiratory Burst Involved In Defense Response
S-adenosylmethionine Cycle
Regulation Of Histone Deacetylase Activity
Negative Regulation Of Telomere Maintenance Via Telomerase
Negative Regulation Of Sodium Ion Transmembrane Transporter Activity
MRNA Localization Resulting In Posttranscriptional Regulation Of Gene Expression
Regulation Of Cell Communication By Electrical Coupling Involved In Cardiac Conduction
Viral Process
Protein Import
Base Conversion Or Substitution Editing
Nuclear Pore Complex Assembly
Negative Regulation Of Sodium Ion Transmembrane Transport
Regulation Of Relaxation Of Cardiac Muscle
Establishment Of Localization In Cell
Protein Localization To Nucleus
Ribosomal Large Subunit Export From Nucleus
Regulation Of Cardiac Muscle Cell Action Potential
Nucleocytoplasmic Transport
Nuclear Transport
Cytoplasmic Transport
Intracellular Transport
Protein Transport
Establishment Of Protein Localization
Establishment Of Localization In Cell
Intracellular Protein Transport
Nuclear Import
Protein Localization
Cellular Localization
Protein Localization To Nucleus
Protein Import Into Nucleus
Viral Process
Cellular Protein Localization
Protein Import
Establishment Of Protein Localization To Organelle
RNA Transport
RNA Localization
Protein Localization To Organelle
Protein Targeting
Protein Export From Nucleus
Nuclear Export
Transport
Ribosomal Protein Import Into Nucleus
Positive Regulation Of Ran GTPase Activity
Viral Life Cycle
MRNA Transport
Cellular Response To Organic Substance
Mitotic Cell Cycle
Mitotic Nuclear Envelope Disassembly
Nuclear Envelope Disassembly
NLS-bearing Protein Import Into Nucleus
Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway
Response To Organic Substance
Regulation Of Nucleocytoplasmic Transport
Cell Cycle
Positive Regulation Of Metabolic Process
Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway
Transforming Growth Factor Beta Receptor Signaling Pathway
Cell Cycle Process
Nuclear Envelope Organization
Mitotic Cell Cycle Process
Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway
Enzyme Linked Receptor Protein Signaling Pathway
Regulation Of Protein Export From Nucleus
Intracellular Transport Of Virus
Regulation Of Intracellular Transport
Cellular Response To Transforming Growth Factor Beta Stimulus
Viral Transcription
Tagcloud
?
5a
accessible
actually
arginine
bandshift
bi
cargo
characterised
directional
dissociated
export
exports
gtpase
heterodimer
import
imported
importin
localisation
masks
multimeric
nes
nls
nucleoplasm
overlaps
rab
rev
rip
shuttle
unspliced
Tagcloud (Difference)
?
5a
accessible
actually
arginine
bandshift
bi
cargo
characterised
directional
dissociated
export
exports
gtpase
heterodimer
import
imported
importin
localisation
masks
multimeric
nes
nls
nucleoplasm
overlaps
rab
rev
rip
shuttle
unspliced
Tagcloud (Intersection)
?