SNX12 and ARL6IP1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		SNX12	ARL6IP1
Description		sorting nexin 12	ARL6 interacting reticulophagy regulator 1
Image			No pdb structure
GO Annotations	Cellular Component	Early Endosome Membrane Retromer Complex Early Endosome Membrane	Cytoplasm Endoplasmic Reticulum Sec61 Translocon Complex Endoplasmic Reticulum Membrane Cytosol Endomembrane System Membrane Endoplasmic Reticulum Tubular Network
	Molecular Function	Protein Binding Lipid Binding Enzyme Binding Phosphatidylinositol-3-phosphate Binding Phosphatidylinositol Binding	Protein Binding Identical Protein Binding
	Biological Process	Negative Regulation Of Gene Expression Negative Regulation Of Protein Processing Protein Transport Regulation Of Endocytosis Endocytic Recycling Late Endosome To Golgi Transport Negative Regulation Of Protein Catabolic Process Negative Regulation Of Protein Transport Negative Regulation Of Early Endosome To Late Endosome Transport	Positive Regulation Of L-glutamate Import Across Plasma Membrane Cotranslational Protein Targeting To Membrane Apoptotic Process Negative Regulation Of Apoptotic Process Endoplasmic Reticulum Tubular Network Formation Regulation Of Endoplasmic Reticulum Tubular Network Organization Endoplasmic Reticulum Tubular Network Membrane Organization
Pathways
Drugs
Diseases
GWAS			Caffeine consumption from coffee or tea ( 33287642) Refractive error ( 32231278)
Interacting Genes		3 interacting genes: ARL6IP1 FKBP7 RPRM	78 interacting genes: ACSF2 AQP6 ARL4D ARL6 BCL2L13 C19orf18 CERT1 DIABLO DRC4 EHD3 EMP1 F2RL1 FBXW7 FDFT1 FXR2 GAD2 GOLPH3 GOLPH3L GORASP2 GPR151 GPR152 HGS HMGCL HSD17B13 INPP5K LMNA MCEMP1 MGST3 MIEF2 MTERF3 MYG1 NAPB NDRG4 NTAQ1 NUDT3 PAM16 PBX3 PICK1 PTPN9 RAB33A REEP6 RETREG3 RNF5 SDCBP SENP2 SHISA5 SHMT2 SLC10A6 SLC13A1 SLC35H1 SLC61A1 SLC71A2 SNX1 SNX10 SNX11 SNX12 SNX15 SNX2 SNX3 SNX4 SNX8 SPG21 STARD4 SUCLA2 TARS2 TFAM TMED8 TMEM14B TMEM248 TMEM258 TUFM UBE2I VMA21 WDFY2 WIPI2 YIPF4 ZFYVE21 ZNF391
Entrez ID		29934	23204
HPRD ID		06719	09641
Ensembl ID		ENSG00000147164	ENSG00000170540
Uniprot IDs		Q3SYF1 Q9UMY4	Q15041
PDB IDs		2CSK
Enriched GO Terms of Interacting Partners?		Sec61 Translocon Complex Endoplasmic Reticulum Tubular Network Membrane Organization Positive Regulation Of L-glutamate Import Across Plasma Membrane Regulation Of Endoplasmic Reticulum Tubular Network Organization Endoplasmic Reticulum Membrane Organization Regulation Of L-glutamate Import Across Plasma Membrane Endoplasmic Reticulum Tubular Network Formation Cotranslational Protein Targeting To Membrane Pore Complex Regulation Of Synaptic Assembly At Neuromuscular Junction FK506 Binding Endoplasmic Reticulum Tubular Network Endoplasmic Reticulum Tubular Network Organization Positive Regulation Of Amino Acid Transport Pore Complex Assembly Synaptic Vesicle Transport Neurotransmitter Secretion Peptidyl-prolyl Cis-trans Isomerase Activity	Lipid Binding Phosphatidylinositol Binding Cellular Localization Establishment Of Protein Localization Retromer Complex Intracellular Transport Protein Transport Membrane Establishment Of Localization In Cell Leptin Receptor Binding Localization Within Membrane Intracellular Protein Transport Early Endosome To Golgi Transport Intracellular Protein Localization Vesicle-mediated Transport To The Plasma Membrane Golgi Vesicle Transport Retrograde Transport, Endosome To Golgi Endosome Phosphatidylinositol-4-phosphate Binding Transferrin Receptor Binding Negative Regulation Of Early Endosome To Late Endosome Transport Endosomal Transport Endocytic Recycling Cytosolic Transport Early Endosome Membrane Phosphatidylinositol-3-phosphate Binding Protein Targeting To Golgi Apparatus Protein Binding Mitochondrial Matrix Early Endosome Retromer, Tubulation Complex Golgi Vesicle Budding Cargo Adaptor Activity Establishment Of Protein Localization To Plasma Membrane Insulin Receptor Binding Vesicle-mediated Transport Organelle Organization Phosphatidylinositol Phosphate Binding Late Endosome To Golgi Transport Succinate Metabolic Process Lamellipodium Morphogenesis Epidermal Growth Factor Receptor Binding Vesicle Budding From Membrane Protein Localization To Membrane Vesicle Organization Positive Regulation Of Exocytosis Regulation Of Establishment Of Protein Localization Membrane Organization Golgi Cisterna Regulation Of Protein Localization
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