SNX12 and RPRM

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		SNX12	RPRM
Description		sorting nexin 12	reprimo, TP53 dependent G2 arrest mediator homolog
Image			No pdb structure
GO Annotations	Cellular Component	Early Endosome Membrane Retromer Complex Early Endosome Membrane	Cytoplasm Membrane
	Molecular Function	Protein Binding Lipid Binding Enzyme Binding Phosphatidylinositol-3-phosphate Binding Phosphatidylinositol Binding	Protein Binding
	Biological Process	Negative Regulation Of Gene Expression Negative Regulation Of Protein Processing Protein Transport Regulation Of Endocytosis Endocytic Recycling Late Endosome To Golgi Transport Negative Regulation Of Protein Catabolic Process Negative Regulation Of Protein Transport Negative Regulation Of Early Endosome To Late Endosome Transport	Regulation Of Mitotic Cell Cycle Regulation Of Cell Cycle
Pathways
Drugs
Diseases
GWAS			Anti-saccade response ( 29064472) Blood trace element (Zn levels) ( 23720494) Heel bone mineral density ( 30598549) Lung cancer ( 28604730) Recurrent major depressive disorder x sex interaction ( 34099189)
Interacting Genes		3 interacting genes: ARL6IP1 FKBP7 RPRM	80 interacting genes: ADGRG3 AMIGO1 AQP6 ARFIP1 ASGR2 BNIP3 BSCL2 BTNL9 C16orf54 CD33 CD53 CD69 CLDN5 CLDN7 CLDN9 CLEC17A CLEC2D COQ8A CREB3 CXorf66 EHHADH EMP1 FAM209A FAM210B FATE1 FBXL19 FCGR1A FFAR2 FGD2 FKBP7 FNDC9 GAD2 GJA5 GJB3 GJB5 GNG13 GPR37L1 GPR42 GPX8 HHLA2 HIP1 HSD17B13 KCNJ6 LAPTM5 LHFPL5 LMNA LPAR6 MPP1 MS4A4A MTIF3 OPRD1 OPRM1 PBX3 PDZK1IP1 PLEKHF2 PNKP SCAND1 SDCBP SENP2 SLC18A1 SLC38A1 SMIM3 SNX11 SNX12 SNX3 SPACA1 SPCS1 STOM SUSD3 SYT16 TM4SF18 TMEM106C TMEM237 TMEM79 TMEM80 TMEM86B TSPO2 TTPA WDFY2 ZDHHC22
Entrez ID		29934	56475
HPRD ID		06719	18002
Ensembl ID		ENSG00000147164	ENSG00000177519
Uniprot IDs		Q3SYF1 Q9UMY4	Q9NS64
PDB IDs		2CSK
Enriched GO Terms of Interacting Partners?		Sec61 Translocon Complex Endoplasmic Reticulum Tubular Network Membrane Organization Positive Regulation Of L-glutamate Import Across Plasma Membrane Regulation Of Endoplasmic Reticulum Tubular Network Organization Endoplasmic Reticulum Membrane Organization Regulation Of L-glutamate Import Across Plasma Membrane Endoplasmic Reticulum Tubular Network Formation Cotranslational Protein Targeting To Membrane Pore Complex Regulation Of Synaptic Assembly At Neuromuscular Junction FK506 Binding Endoplasmic Reticulum Tubular Network Endoplasmic Reticulum Tubular Network Organization Positive Regulation Of Amino Acid Transport Pore Complex Assembly Synaptic Vesicle Transport Neurotransmitter Secretion Peptidyl-prolyl Cis-trans Isomerase Activity	Membrane Protein Binding Plasma Membrane Negative Regulation Of Early Endosome To Late Endosome Transport Connexin Complex Calcium-independent Cell-cell Adhesion Via Plasma Membrane Cell-adhesion Molecules Gap Junction Channel Activity Endoplasmic Reticulum Phosphatidylinositol Binding External Side Of Plasma Membrane Gap Junction Gamma-aminobutyric Acid Biosynthetic Process Phosphatidylinositol Phosphate Binding Late Endosome To Golgi Transport
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