UBIAD1 and MGST3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		UBIAD1	MGST3
Description		UbiA prenyltransferase domain containing 1	microsomal glutathione S-transferase 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Nucleus Cytoplasm Mitochondrion Endoplasmic Reticulum Endoplasmic Reticulum Membrane Golgi Apparatus Endomembrane System Membrane Organelle Membrane Mitochondrial Membrane	Nuclear Envelope Mitochondrion Mitochondrial Outer Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane
	Molecular Function	Prenyltransferase Activity Protein Binding Antioxidant Activity Transferase Activity Transferase Activity, Transferring Alkyl Or Aryl (other Than Methyl) Groups	Glutathione Transferase Activity Leukotriene-C4 Synthase Activity Glutathione Peroxidase Activity Protein Binding Oxidoreductase Activity Transferase Activity Lyase Activity Identical Protein Binding
	Biological Process	Ubiquinone Biosynthetic Process Menaquinone Metabolic Process Menaquinone Biosynthetic Process Vitamin K Biosynthetic Process Vitamin K Metabolic Process Cellular Oxidant Detoxification	Lipid Metabolic Process Leukotriene Metabolic Process Prostanoid Metabolic Process Arachidonate Metabolic Process Leukotriene Biosynthetic Process Cellular Oxidant Detoxification
Pathways		Metabolism of vitamin K	Glutathione conjugation Aflatoxin activation and detoxification
Drugs			Glutathione
Diseases		Schnyder corneal dystrophy (SCD); Schnyder crystalline corneal dystrophy (SCCD); Crystalline stromal dystrophy; Schnyder crystalline dystrophy sine crystals
GWAS		Beard thickness ( 26926045) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223) Intraocular pressure ( 29785010) Weight ( 28552196)	Metabolite levels ( 23823483) Total ventricular volume ( 21116278)
Interacting Genes		43 interacting genes: AHNAK2 AQP6 ASGR2 BIK CD33 CD53 CD79A CLDN7 CPLX4 CRB3 CREB3L1 CYB5R3 EBP ELOVL4 ERGIC3 EVI2A EVI2B FAM209A FCER1G FKBP7 FNDC9 GPR152 HIBADH KCNJ6 LHFPL5 MGST3 MRM3 NCAPH2 PHACTR3 PIGP REEP4 RETREG3 SAR1A SCN3B SLC10A1 SLC10A6 SLC7A14 SYT1 TIMMDC1 TMEFF2 TMEM139 TMEM14B VEGFA	86 interacting genes: AGPAT4 AGTRAP APOD APOL2 AQP1 AQP10 AQP3 ARL6IP1 ARL6IP6 BET1 BMP10 C11orf24 C14orf180 C3orf52 CACNG1 CCNC CDIPT CLCA4 CLRN1 CMTM5 CREB3L1 CTSA CYBC1 ERG28 F10 FAXDC2 FUNDC2 FXYD6 GIMAP1 GIMAP5 GPR152 GPX8 GRM2 HMOX2 ITGAM LEMD1 LMNA LPAR3 LRP10 MIP MRM1 MTIF3 NEU1 NINJ2 NKG7 NRM NSG1 PAGE1 PLN PLP1 PLP2 PLPP4 SCD SCN3B SEC22B SLC1A3 SLC2A5 SLC35A1 SLC39A9 SLC7A1 SMCO4 SNAP47 SNORC STX3 STX7 STX8 SYS1 TFAM TFRC TMEM107 TMEM109 TMEM120B TMEM140 TMEM229B TMEM60 TMEM86B TMX2 TSPAN12 TSPAN2 TSPAN33 UBIAD1 UNC50 VAMP3 VAMP4 YIF1A ZFPL1
Entrez ID		29914	4259
HPRD ID		15487	05192
Ensembl ID		ENSG00000120942	ENSG00000143198
Uniprot IDs		Q9Y5Z9	O14880 Q5VV89
PDB IDs
Enriched GO Terms of Interacting Partners?		Membrane Protein Binding Bile Acid:sodium Symporter Activity	Membrane SNAP Receptor Activity SNARE Complex Endoplasmic Reticulum Membrane Protein Binding Endoplasmic Reticulum Water Channel Activity Plasma Membrane Glycerol Transmembrane Transport Organelle Fusion Water Transport Polyol Transmembrane Transport Vesicle Fusion Membrane Fusion Organelle Membrane Fusion Fluid Transport Vesicle Organization Channel Activity Endomembrane System Vesicle-mediated Transport Carbohydrate Transmembrane Transport Carbohydrate Transport Nuclear Inner Membrane Transport Vesicle Establishment Of Protein Localization To Plasma Membrane Glycerol Channel Activity Vesicle Docking One-carbon Compound Transport Acute Inflammatory Response Renal Water Absorption Urea Transmembrane Transporter Activity IgG Receptor Activity Protein Localization To Plasma Membrane Membrane Organization Regulation Of Postsynaptic Membrane Neurotransmitter Receptor Levels Chloride Channel Inhibitor Activity Renal Water Transport Antibody-dependent Cellular Cytotoxicity Fc-gamma Receptor Signaling Pathway Organelle Localization By Membrane Tethering Response To Hypoxia Golgi To Plasma Membrane Protein Transport Urea Transmembrane Transport Neurotransmitter Receptor Transport, Endosome To Postsynaptic Membrane Neurotransmitter Receptor Transport, Endosome To Plasma Membrane Response To Decreased Oxygen Levels Ventricular Cardiac Muscle Cell Development Membrane Docking Neurotransmitter Receptor Transport To Postsynaptic Membrane Protein Localization To Cell Periphery
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