UBIAD1 and TMEM139

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		UBIAD1	TMEM139
Description		UbiA prenyltransferase domain containing 1	transmembrane protein 139
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Nucleus Cytoplasm Mitochondrion Endoplasmic Reticulum Endoplasmic Reticulum Membrane Golgi Apparatus Endomembrane System Membrane Organelle Membrane Mitochondrial Membrane	Membrane
	Molecular Function	Prenyltransferase Activity Protein Binding Antioxidant Activity Transferase Activity Transferase Activity, Transferring Alkyl Or Aryl (other Than Methyl) Groups	Protein Binding
	Biological Process	Ubiquinone Biosynthetic Process Menaquinone Metabolic Process Menaquinone Biosynthetic Process Vitamin K Biosynthetic Process Vitamin K Metabolic Process Cellular Oxidant Detoxification
Pathways		Metabolism of vitamin K
Drugs
Diseases		Schnyder corneal dystrophy (SCD); Schnyder crystalline corneal dystrophy (SCCD); Crystalline stromal dystrophy; Schnyder crystalline dystrophy sine crystals
GWAS		Beard thickness ( 26926045) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223) Intraocular pressure ( 29785010) Weight ( 28552196)
Interacting Genes		43 interacting genes: AHNAK2 AQP6 ASGR2 BIK CD33 CD53 CD79A CLDN7 CPLX4 CRB3 CREB3L1 CYB5R3 EBP ELOVL4 ERGIC3 EVI2A EVI2B FAM209A FCER1G FKBP7 FNDC9 GPR152 HIBADH KCNJ6 LHFPL5 MGST3 MRM3 NCAPH2 PHACTR3 PIGP REEP4 RETREG3 SAR1A SCN3B SLC10A1 SLC10A6 SLC7A14 SYT1 TIMMDC1 TMEFF2 TMEM139 TMEM14B VEGFA	41 interacting genes: ABHD16A AGTRAP APOL2 ATP6V0C BCL2L2 CD151 CDS2 CLN6 CMTM5 CTSA CXCL16 CYB5B FAXDC2 KCNK1 MALL MARCHF5 MIP NAPB NEDD4 NINJ2 NKG7 NSG1 PLPP4 PMP22 SEC22B SFTPC SLC30A8 SLC35A1 SMCO4 SMURF2 TMEM107 TMEM120B TMEM19 TMEM60 TRAF3IP3 UBIAD1 UPK1B VAMP5 YAP1 YIF1A ZFPL1
Entrez ID		29914	135932
HPRD ID		15487	08298
Ensembl ID		ENSG00000120942	ENSG00000178826
Uniprot IDs		Q9Y5Z9	Q8IV31
PDB IDs
Enriched GO Terms of Interacting Partners?		Membrane Protein Binding Bile Acid:sodium Symporter Activity	Membrane Endoplasmic Reticulum Membrane Golgi Membrane
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