TAF13 and TAF15

Number of citations of the paper that reports this interaction (PubMedID 9488465)
39

Data Source:
BioGRID (affinity chromatography technology)
HPRD (in vivo, in vitro)

		TAF13	TAF15
Description		TATA-box binding protein associated factor 13	TATA-box binding protein associated factor 15
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Transcription Factor TFIID Complex Nucleolus	Nucleus Nucleoplasm Nucleolus Cytoplasm
	Molecular Function	DNA Binding Protein Binding RNA Polymerase II General Transcription Initiation Factor Activity TBP-class Protein Binding Protein Heterodimerization Activity	Nucleic Acid Binding DNA Binding Transcription Coregulator Activity RNA Binding MRNA 3'-UTR Binding Protein Binding Zinc Ion Binding Metal Ion Binding
	Biological Process	DNA-templated Transcription Initiation Transcription By RNA Polymerase II Transcription Initiation At RNA Polymerase II Promoter MRNA Transcription By RNA Polymerase II RNA Polymerase II Preinitiation Complex Assembly Positive Regulation Of Transcription Initiation By RNA Polymerase II	Regulation Of DNA-templated Transcription RNA Splicing Gene Expression Positive Regulation Of DNA-templated Transcription MRNA Stabilization
Pathways		HIV Transcription Initiation RNA Polymerase II HIV Promoter Escape Transcription of the HIV genome RNA Polymerase II Pre-transcription Events Regulation of TP53 Activity through Phosphorylation RNA polymerase II transcribes snRNA genes RNA polymerase II transcribes snRNA genes RNA Polymerase II Promoter Escape RNA Polymerase II Transcription Pre-Initiation And Promoter Opening RNA Polymerase II Transcription Initiation RNA Polymerase II Transcription Initiation And Promoter Clearance	HIV Transcription Initiation RNA Polymerase II HIV Promoter Escape Transcription of the HIV genome RNA Polymerase II Pre-transcription Events Regulation of TP53 Activity through Phosphorylation RNA Polymerase II Promoter Escape RNA Polymerase II Transcription Pre-Initiation And Promoter Opening RNA Polymerase II Transcription Initiation RNA Polymerase II Transcription Initiation And Promoter Clearance
Drugs
Diseases			Extraskeletal myxoid chondrosarcoma
GWAS			Reticulocyte count ( 27863252) Reticulocyte fraction of red cells ( 27863252)
Interacting Genes		7 interacting genes: CPSF1 H3-4 MTUS2 TAF10 TAF11 TAF15 TBP	95 interacting genes: ARID1A CACNA1A H2AC20 H3-4 H3C1 H4C14 ITCH MIR1-1 MIR1-2 MIR106A MIR106B MIR107 MIR10B MIR122 MIR128-1 MIR128-2 MIR138-1 MIR138-2 MIR140 MIR141 MIR143 MIR145 MIR155 MIR15A MIR15B MIR16-1 MIR16-2 MIR17 MIR18A MIR18B MIR199A1 MIR199A2 MIR19A MIR19B1 MIR19B2 MIR200A MIR200B MIR200C MIR205 MIR206 MIR20A MIR20B MIR21 MIR214 MIR221 MIR222 MIR25 MIR29A MIR29B1 MIR29B2 MIR29C MIR31 MIR34A MIR34B MIR34C MIR363 MIR429 MIR451A MIR7-1 MIR7-2 MIR7-3 MIR9-1 MIR9-2 MIR9-3 MIR92A1 MIR92A2 MIR93 MIR98 MIRLET7A1 MIRLET7A2 MIRLET7A3 MIRLET7B MIRLET7C MIRLET7D MIRLET7E MIRLET7F1 MIRLET7F2 MIRLET7G MIRLET7I OGT POLR2C POLR2E POLR2G SAFB SF1 SMARCA4 SMARCC1 SMARCC2 TAF1 TAF12 TAF13 TAF5 TAF7 YWHAG ZNF384
Entrez ID		6884	8148
HPRD ID		11864	09031
Ensembl ID		ENSG00000197780	ENSG00000270647
Uniprot IDs		Q15543	Q92804
PDB IDs		1BH8 1BH9 6MZD 6MZL 7EDX 7EG7 7EG8 7EG9 7EGA 7EGB 7EGC 7EGD 7EGE 7EGF 7EGI 7EGJ 7ENA 7ENC 8GXQ 8GXS 8WAK 8WAL 8WAN 8WAO 8WAP 8WAQ 8WAR 8WAS	2MMY 8ONS
Enriched GO Terms of Interacting Partners?		MRNA Transcription By RNA Polymerase II Transcription Factor TFIID Complex RNA Polymerase II General Transcription Initiation Factor Activity Protein-DNA Complex Assembly RNA Polymerase II Preinitiation Complex Assembly Transcription Initiation At RNA Polymerase II Promoter MRNA Transcription Transcription Preinitiation Complex Assembly Positive Regulation Of Transcription Initiation By RNA Polymerase II Positive Regulation Of DNA-templated Transcription Initiation Regulation Of Transcription Initiation By RNA Polymerase II DNA-templated Transcription Initiation Regulation Of DNA-templated Transcription Initiation MRNA Metabolic Process Transcription By RNA Polymerase II Male Germ Cell Nucleus SAGA Complex Assembly Enzyme Binding DNA-templated Transcription Nucleoplasm Lateral Mesodermal Cell Differentiation Protein-containing Complex Assembly Nucleus RNA Metabolic Process Protein-containing Complex Organization Macromolecule Biosynthetic Process Allantois Development TFIIB-class Transcription Factor Binding Spermatogonial Cell Division RNA Polymerase Transcription Factor SL1 Complex Transcription Factor TFIIA Complex Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription RNA Polymerase II General Transcription Initiation Factor Binding Pronucleus DNA Replication-dependent Chromatin Assembly Positive Regulation Of RNA Metabolic Process Male Pronucleus Aryl Hydrocarbon Receptor Binding RNA Polymerase I Core Promoter Sequence-specific DNA Binding Nucleobase-containing Compound Biosynthetic Process RNA Polymerase I Preinitiation Complex Assembly Female Pronucleus Co-transcriptional RNA 3'-end Processing, Cleavage And Polyadenylation Pathway Positive Regulation Of Nucleobase-containing Compound Metabolic Process Nucleic Acid Metabolic Process RNA Polymerase III General Transcription Initiation Factor Activity Transcription Preinitiation Complex Female Germ Cell Nucleus Gene Expression	MiRNA-mediated Post-transcriptional Gene Silencing RISC Complex Regulatory NcRNA-mediated Post-transcriptional Gene Silencing Post-transcriptional Gene Silencing Regulatory NcRNA-mediated Gene Silencing MRNA Base-pairing Post-transcriptional Repressor Activity Post-transcriptional Regulation Of Gene Expression Negative Regulation Of Gene Expression MRNA 3'-UTR Binding Negative Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Biosynthetic Process MiRNA-mediated Gene Silencing By Inhibition Of Translation Negative Regulation Of Macromolecule Metabolic Process Negative Regulation Of Metabolic Process MiRNA-mediated Gene Silencing By MRNA Destabilization Regulation Of Gene Expression Extracellular Vesicle Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Translation Regulation Of Macromolecule Metabolic Process Regulation Of Metabolic Process Positive Regulation Of MRNA Catabolic Process MRNA Destabilization RNA Destabilization Negative Regulation Of Cytokine Production Negative Regulation Of Cell Migration Positive Regulation Of MRNA Metabolic Process Negative Regulation Of Cell Motility Negative Regulation Of Locomotion Negative Regulation Of Angiogenesis Negative Regulation Of Vasculature Development Regulation Of Translation Negative Regulation Of Vascular Endothelial Growth Factor Production Regulation Of Angiogenesis Regulation Of Vasculature Development Negative Regulation Of Protein Metabolic Process Negative Regulation Of Multicellular Organismal Process Negative Regulation Of Developmental Process Regulation Of MRNA Stability Regulation Of RNA Stability Negative Regulation Of Signal Transduction Regulation Of Blood Vessel Endothelial Cell Migration Negative Regulation Of Signaling Negative Regulation Of Cell Communication Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Regulation Of MRNA Metabolic Process Regulation Of Endothelial Cell Migration Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Regulation Of Cellular Response To Growth Factor Stimulus Negative Regulation Of Blood Vessel Endothelial Cell Migration
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