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GUCY1B3 and AGAP1
Number of citations of the paper that reports this interaction (PMID
15381706
)
7
Data Source:
HPRD
(in vivo, two hybrid)
GUCY1B3
AGAP1
Gene Name
guanylate cyclase 1, soluble, beta 3
ArfGAP with GTPase domain, ankyrin repeat and PH domain 1
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Cytoplasm
Guanylate Cyclase Complex, Soluble
Intracellular Membrane-bounded Organelle
Cytoplasm
Molecular Function
Guanylate Cyclase Activity
Receptor Activity
GTP Binding
Heme Binding
Metal Ion Binding
Protein Heterodimerization Activity
Hsp90 Protein Binding
GTP Binding
Phospholipid Binding
ARF GTPase Activator Activity
Zinc Ion Binding
Biological Process
CGMP Biosynthetic Process
Nitric Oxide Mediated Signal Transduction
Blood Coagulation
Blood Circulation
Small GTPase Mediated Signal Transduction
Protein Transport
Regulation Of ARF GTPase Activity
Positive Regulation Of GTPase Activity
Pathways
Platelet homeostasis
Nitric oxide stimulates guanylate cyclase
Drugs
Diseases
GWAS
Blood pressure (
21909110
)
Diastolic blood pressure (
21909115
)
Systolic blood pressure (
21909115
)
Menarche (age at onset) (
23667675
)
Protein-Protein Interactions
4 interactors:
AGAP1
APP
GUCY1A2
HSP90AA1
6 interactors:
APP
GRB7
GUCY1A3
GUCY1B3
SMN1
TK1
Entrez ID
2983
116987
HPRD ID
00769
16359
Ensembl ID
ENSG00000061918
ENSG00000157985
Uniprot IDs
D6RC99
E9PCN2
Q02153
B2RZG9
Q9UPQ3
PDB IDs
2WZ1
3UVJ
Enriched GO Terms of Interacting Partners
?
Synaptic Growth At Neuromuscular Junction
Positive Regulation Of Metabolic Process
Collateral Sprouting In Absence Of Injury
Protein Import Into Mitochondrial Outer Membrane
Collateral Sprouting
Axon Midline Choice Point Recognition
Smooth Endoplasmic Reticulum Calcium Ion Homeostasis
Axon Choice Point Recognition
Positive Regulation Of Cellular Biosynthetic Process
Neuron Remodeling
Axon Guidance
Blood Coagulation
Hemostasis
Chaperone-mediated Protein Complex Assembly
Signal Transduction
Axonogenesis
Positive Regulation Of CGMP Biosynthetic Process
Cellular Copper Ion Homeostasis
Positive Regulation Of CGMP Metabolic Process
Signaling
CGMP Biosynthetic Process
Protein Refolding
Axon Development
Regulation Of Body Fluid Levels
Cell Communication
Cell Morphogenesis Involved In Neuron Differentiation
Small Molecule Metabolic Process
Wound Healing
Chemotaxis
Regulation Of CGMP Biosynthetic Process
Copper Ion Homeostasis
Suckling Behavior
Regulation Of Catalytic Activity
Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle
Neuron Projection Morphogenesis
Endocytosis
Nitric Oxide Metabolic Process
Positive Regulation Of Cellular Metabolic Process
CGMP Metabolic Process
Neuron Maturation
MRNA Polyadenylation
Regulation Of Cellular Response To Heat
Regulation Of Epidermal Growth Factor-activated Receptor Activity
Response To Wounding
Reactive Nitrogen Species Metabolic Process
Regulation Of CGMP Metabolic Process
Cell Morphogenesis Involved In Differentiation
Mating Behavior
Endoplasmic Reticulum Calcium Ion Homeostasis
Cellular Response To Stimulus
Blood Coagulation
Hemostasis
Regulation Of Body Fluid Levels
Wound Healing
Nitric Oxide Mediated Signal Transduction
CGMP Biosynthetic Process
Response To Wounding
CGMP Metabolic Process
Cyclic Purine Nucleotide Metabolic Process
Nucleotide Biosynthetic Process
Cyclic Nucleotide Biosynthetic Process
Cyclic Nucleotide Metabolic Process
Nucleotide Metabolic Process
Fetal Process Involved In Parturition
Nucleobase-containing Small Molecule Metabolic Process
Response To Defense-related Host Nitric Oxide Production
Skeletal Muscle Cell Proliferation
Synaptic Growth At Neuromuscular Junction
Second-messenger-mediated Signaling
Cellular Component Assembly
Collateral Sprouting In Absence Of Injury
Purine Nucleotide Biosynthetic Process
Ribose Phosphate Biosynthetic Process
Ribonucleoprotein Complex Assembly
Collateral Sprouting
Axon Midline Choice Point Recognition
Small Molecule Metabolic Process
Nucleobase-containing Compound Metabolic Process
Smooth Endoplasmic Reticulum Calcium Ion Homeostasis
Response To Cortisol
Thymidine Metabolic Process
Organophosphate Metabolic Process
Response To Host Immune Response
Axon Choice Point Recognition
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Deoxyribonucleoside Monophosphate Biosynthetic Process
Regulation Of Translation
Relaxation Of Vascular Smooth Muscle
Cellular Nitrogen Compound Metabolic Process
Ribonucleotide Metabolic Process
Neuron Remodeling
Relaxation Of Smooth Muscle
Pyrimidine Nucleoside Salvage
Pyrimidine-containing Compound Salvage
Purine Nucleotide Metabolic Process
Blood Circulation
Ribose Phosphate Metabolic Process
Phosphate-containing Compound Metabolic Process
Ribonucleoprotein Complex Biogenesis
Tagcloud
?
2j
6j
buffer
bxd
coexpression
congruent
crosses
dba
distal
extraordinary
fluctuation
gaba
gabra1
gabra2
gabrb2
gabrb3
gabrg2
heritable
massive
naaa
neurotransmission
nos1
platforms
remarkably
subunits
unlinked
utrs
zkscan1
Tagcloud (Difference)
?
2j
6j
buffer
bxd
coexpression
congruent
crosses
dba
distal
extraordinary
fluctuation
gaba
gabra1
gabra2
gabrb2
gabrb3
gabrg2
heritable
massive
naaa
neurotransmission
nos1
platforms
remarkably
subunits
unlinked
utrs
zkscan1
Tagcloud (Intersection)
?