GUCY1B3

Gene Name		guanylate cyclase 1, soluble, beta 3
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Gene Ontology Annotations	Cellular Component	Cytoplasm Guanylate Cyclase Complex, Soluble Intracellular Membrane-bounded Organelle
	Molecular Function	Guanylate Cyclase Activity Receptor Activity GTP Binding Heme Binding Metal Ion Binding Protein Heterodimerization Activity Hsp90 Protein Binding
	Biological Process	CGMP Biosynthetic Process Nitric Oxide Mediated Signal Transduction Blood Coagulation Blood Circulation
Pathways		Platelet homeostasis Nitric oxide stimulates guanylate cyclase
Drugs
Diseases
GWAS		Blood pressure ( 21909110) Diastolic blood pressure ( 21909115) Systolic blood pressure ( 21909115)
Protein-protein Interactions		4 interactors: AGAP1 APP GUCY1A2 HSP90AA1
Entrez ID		2983
HPRD ID		00769
Ensembl ID		ENSG00000061918
Uniprot IDs		D6RC99 E9PCN2 Q02153
PDB IDs		2WZ1 3UVJ
Enriched GO Terms of Interacting Partners?		Synaptic Growth At Neuromuscular Junction Positive Regulation Of Metabolic Process Collateral Sprouting In Absence Of Injury Protein Import Into Mitochondrial Outer Membrane Collateral Sprouting Axon Midline Choice Point Recognition Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Axon Choice Point Recognition Positive Regulation Of Cellular Biosynthetic Process Neuron Remodeling Axon Guidance Blood Coagulation Hemostasis Chaperone-mediated Protein Complex Assembly Signal Transduction Axonogenesis Positive Regulation Of CGMP Biosynthetic Process Cellular Copper Ion Homeostasis Positive Regulation Of CGMP Metabolic Process Signaling CGMP Biosynthetic Process Protein Refolding Axon Development Regulation Of Body Fluid Levels Cell Communication Cell Morphogenesis Involved In Neuron Differentiation Small Molecule Metabolic Process Wound Healing Chemotaxis Regulation Of CGMP Biosynthetic Process Copper Ion Homeostasis Suckling Behavior Regulation Of Catalytic Activity Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Neuron Projection Morphogenesis Endocytosis Nitric Oxide Metabolic Process Positive Regulation Of Cellular Metabolic Process CGMP Metabolic Process Neuron Maturation MRNA Polyadenylation Regulation Of Cellular Response To Heat Regulation Of Epidermal Growth Factor-activated Receptor Activity Response To Wounding Reactive Nitrogen Species Metabolic Process Regulation Of CGMP Metabolic Process Cell Morphogenesis Involved In Differentiation Mating Behavior Endoplasmic Reticulum Calcium Ion Homeostasis Cellular Response To Stimulus
Tagcloud ?		2j 6j buffer bxd coexpression congruent crosses dba distal extraordinary fluctuation gaba gabra1 gabra2 gabrb2 gabrb3 gabrg2 heritable massive naaa neurotransmission nos1 platforms remarkably subunits unlinked utrs zkscan1