GUCA1A and KATNAL1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		GUCA1A	KATNAL1
Description		guanylate cyclase activator 1A	katanin catalytic subunit A1 like 1
Image		No pdb structure
GO Annotations	Cellular Component	Photoreceptor Outer Segment Photoreceptor Inner Segment Membrane Cell Projection Photoreceptor Disc Membrane Cone Photoreceptor Outer Segment	Spindle Pole Cytoplasm Mitochondrion Centrosome Spindle Cytosol Cytoskeleton Microtubule Katanin Complex Microtubule Cytoskeleton Mitotic Spindle
	Molecular Function	Calcium Ion Binding Protein Binding Calcium Sensitive Guanylate Cyclase Activator Activity Guanylate Cyclase Regulator Activity Metal Ion Binding	Nucleotide Binding Protein Binding ATP Binding Microtubule Binding Microtubule Severing ATPase Activity Isomerase Activity ATP Hydrolysis Activity Identical Protein Binding
	Biological Process	Signal Transduction Visual Perception Phototransduction Regulation Of Signal Transduction Positive Regulation Of CGMP-mediated Signaling Positive Regulation Of Guanylate Cyclase Activity Cellular Response To Calcium Ion	Spermatogenesis Cytoplasmic Microtubule Organization Microtubule Severing
Pathways		Inactivation, recovery and regulation of the phototransduction cascade
Drugs		Myristic acid
Diseases		Cone-rod dystrophy and cone dystrophy, including: Cone-rod dystrophy (CORD); Cone dystrophy (COD); Retinal cone dystrophy (RCD)
GWAS		Femur bone mineral density x serum urate levels interaction ( 34046847) Spatial processing ( 31596458)	Antineutrophil cytoplasmic antibody-associated vasculitis ( 22808956) Blood osmolality (transformed sodium) ( 28360221) Fat distribution (HIV) ( 21897333) Femur bone mineral density x serum urate levels interaction ( 34046847) Male-pattern baldness ( 27182965) Rapid response to perioperative phenylephrine (change in mean arterial pressure) ( 33168928) Refractive error ( 32231278) Type 2 diabetes ( 31049640)
Interacting Genes		9 interacting genes: AGR2 C1QTNF5 DDIT4L DEFB118 GSC2 GUCY2D HSPB1 KATNAL1 PRKAR1B	18 interacting genes: AIRIM ASCC2 BYSL CEP57L1 CFTR COX17 CTNNA3 GCC1 GUCA1A IQUB KATNBL1 KLC4 MEOX2 PGAM2 PITPNC1 SIAH1 VPS4B ZNF69
Entrez ID		2978	84056
HPRD ID		02648	13753
Ensembl ID		ENSG00000048545	ENSG00000102781
Uniprot IDs		P43080	B3KUK7 Q9BW62
PDB IDs			6B5C
Enriched GO Terms of Interacting Partners?
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