KATNAL1 and PGAM2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		KATNAL1	PGAM2
Description		katanin catalytic subunit A1 like 1	phosphoglycerate mutase 2
Image			No pdb structure
GO Annotations	Cellular Component	Spindle Pole Cytoplasm Mitochondrion Centrosome Spindle Cytosol Cytoskeleton Microtubule Katanin Complex Microtubule Cytoskeleton Mitotic Spindle	Nucleus Cytosol Extracellular Exosome
	Molecular Function	Nucleotide Binding Protein Binding ATP Binding Microtubule Binding Microtubule Severing ATPase Activity Isomerase Activity ATP Hydrolysis Activity Identical Protein Binding	Catalytic Activity Bisphosphoglycerate Mutase Activity Phosphoglycerate Mutase Activity Protein Binding Hydrolase Activity Isomerase Activity Intramolecular Phosphotransferase Activity Identical Protein Binding
	Biological Process	Spermatogenesis Cytoplasmic Microtubule Organization Microtubule Severing	Gluconeogenesis Glycolytic Process Striated Muscle Contraction Notch Signaling Pathway Spermatogenesis Response To Mercury Ion Canonical Glycolysis
Pathways			Glycolysis Gluconeogenesis
Drugs			Benzene Hexacarboxylic Acid 3-phospho-D-glyceric acid
Diseases
GWAS		Antineutrophil cytoplasmic antibody-associated vasculitis ( 22808956) Blood osmolality (transformed sodium) ( 28360221) Fat distribution (HIV) ( 21897333) Femur bone mineral density x serum urate levels interaction ( 34046847) Male-pattern baldness ( 27182965) Rapid response to perioperative phenylephrine (change in mean arterial pressure) ( 33168928) Refractive error ( 32231278) Type 2 diabetes ( 31049640)
Interacting Genes		18 interacting genes: AIRIM ASCC2 BYSL CEP57L1 CFTR COX17 CTNNA3 GCC1 GUCA1A IQUB KATNBL1 KLC4 MEOX2 PGAM2 PITPNC1 SIAH1 VPS4B ZNF69	4 interacting genes: CLVS2 DYNC1LI1 KATNAL1 MDM2
Entrez ID		84056	5224
HPRD ID		13753	02027
Ensembl ID		ENSG00000102781	ENSG00000164708
Uniprot IDs		B3KUK7 Q9BW62	P15259
PDB IDs		6B5C
Enriched GO Terms of Interacting Partners?			Endocytic Vesicle Membrane Response To Formaldehyde Cellular Response To Vitamin B1 Response To Vitamin B1 NEDD8 Ligase Activity Response To Actinomycin D Positive Regulation Of Cell Cycle Process Receptor Serine/threonine Kinase Binding Response To Water-immersion Restraint Stress Traversing Start Control Point Of Mitotic Cell Cycle Cellular Response To UV-C Cellular Response To Actinomycin D Regulation Of Protein Catabolic Process At Postsynapse, Modulating Synaptic Transmission Spindle Pole Early Endosome To Recycling Endosome Transport Katanin Complex Microtubule Severing ATPase Activity Regulation Of Mitotic Cell Cycle Phase Transition Atrial Septum Development Fibroblast Activation Peroxisome Proliferator Activated Receptor Binding Cellular Response To Antibiotic Positive Regulation Of Cell Cycle 5S RRNA Binding Microtubule Microtubule Severing Positive Regulation Of Mitotic Cell Cycle Spindle Assembly Checkpoint Phosphatidylinositol Bisphosphate Binding SUMO Transferase Activity Regulation Of Postsynaptic Neurotransmitter Receptor Internalization Cellular Response To Estrogen Stimulus Endocardial Cushion Morphogenesis Regulation Of Cell Cycle Phase Transition Response To Ether Negative Regulation Of Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Response To Magnesium Ion Negative Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator Positive Regulation Of Vascular Associated Smooth Muscle Cell Migration Positive Regulation Of Protein Export From Nucleus Regulation Of Vesicle-mediated Transport Response To Immobilization Stress Heart Valve Development Regulation Of Mitotic Cell Cycle Atrioventricular Valve Morphogenesis Response To UV-C Negative Regulation Of Protein Processing Negative Regulation Of Protein Maturation Supramolecular Fiber Organization Cytoplasmic Dynein Complex Microtubule Cytoskeleton Organization
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