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GUCA1A

Description guanylate cyclase activator 1A
Image No pdb structure
GO Annotations Cellular Component
  • Photoreceptor Outer Segment
  • Photoreceptor Inner Segment
  • Membrane
  • Cell Projection
  • Photoreceptor Disc Membrane
  • Cone Photoreceptor Outer Segment
Molecular Function
  • Calcium Ion Binding
  • Protein Binding
  • Calcium Sensitive Guanylate Cyclase Activator Activity
  • Guanylate Cyclase Regulator Activity
  • Metal Ion Binding
Biological Process
  • Signal Transduction
  • Visual Perception
  • Phototransduction
  • Regulation Of Signal Transduction
  • Positive Regulation Of CGMP-mediated Signaling
  • Positive Regulation Of Guanylate Cyclase Activity
  • Cellular Response To Calcium Ion
Pathways
  • Inactivation, recovery and regulation of the phototransduction cascade
Drugs
  • Myristic acid
Diseases
  • Cone-rod dystrophy and cone dystrophy, including: Cone-rod dystrophy (CORD); Cone dystrophy (COD); Retinal cone dystrophy (RCD)
GWAS
  • Femur bone mineral density x serum urate levels interaction ( 34046847)
  • Spatial processing ( 31596458)
Novel Interacting Genes 1 novel interacting genes: BCKDK
Interacting Genes 9 interacting genes: AGR2 C1QTNF5 DDIT4L DEFB118 GSC2 GUCY2D HSPB1 KATNAL1 PRKAR1B
Entrez ID 2978
HPRD ID 02648
Ensembl ID ENSG00000048545
Uniprot IDs P43080
PDB IDs
Enriched GO Terms of Interacting Partners?
Tagcloud ?

© Madhavi K. Ganapathiraju 2012-2025