GTF3C2 and GTF3A

Number of citations of the paper that reports this interaction (PMID 9171097)
11

Data Source:
HPRD (in vitro)

		GTF3C2	GTF3A
Gene Name		general transcription factor IIIC, polypeptide 2, beta 110kDa	general transcription factor IIIA
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Transcription Factor TFIIIC Complex Nucleoplasm	Nucleus Nucleoplasm
	Molecular Function	DNA Binding	DNA Binding RNA Binding Metal Ion Binding
	Biological Process	Transcription, DNA-templated Transcription From RNA Polymerase III Promoter Gene Expression 5S Class RRNA Transcription From RNA Polymerase III Type 1 Promoter TRNA Transcription From RNA Polymerase III Promoter	Regulation Of Transcription, DNA-templated Transcription From RNA Polymerase III Promoter RRNA Transcription Gene Expression
Pathways		RNA Polymerase III Transcription RNA Polymerase III Transcription Initiation RNA Polymerase III Transcription Initiation From Type 1 Promoter RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription RNA Polymerase III Abortive And Retractive Initiation RNA Polymerase III Transcription Initiation From Type 2 Promoter	RNA Polymerase III Transcription Initiation RNA Polymerase III Transcription RNA Polymerase III Transcription Initiation From Type 1 Promoter RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription RNA Polymerase III Abortive And Retractive Initiation
Drugs
Diseases
GWAS			Body mass index ( 20935630)
Protein-Protein Interactions		5 interactors: GRIA2 GTF3A GTF3C4 RB1 TBP	4 interactors: CHMP5 GTF3C2 OPTN SCYL2
Entrez ID		2976	2971
HPRD ID		05347	02916
Ensembl ID		ENSG00000115207	ENSG00000122034
Uniprot IDs		Q8WUA4	Q92664
PDB IDs
Enriched GO Terms of Interacting Partners?		Transcription From RNA Polymerase III Promoter RRNA Transcription Negative Regulation Of Transcription From RNA Polymerase II Promoter During Mitosis Sister Chromatid Biorientation Transcription, DNA-templated RNA Biosynthetic Process Regulation Of Centromere Complex Assembly Negative Regulation Of Transcription Involved In G1/S Transition Of Mitotic Cell Cycle Maintenance Of Mitotic Sister Chromatid Cohesion Regulation Of Cohesin Localization To Chromatin DNA-templated Transcription, Initiation Attachment Of Mitotic Spindle Microtubules To Kinetochore 5S Class RRNA Transcription From RNA Polymerase III Type 1 Promoter TRNA Transcription From RNA Polymerase III Promoter TRNA Transcription RNA Metabolic Process Positive Regulation Of Mitotic Metaphase/anaphase Transition Glial Cell Apoptotic Process Gene Expression Protein Localization To Chromosome, Centromeric Region Attachment Of Spindle Microtubules To Kinetochore Cellular Macromolecule Biosynthetic Process Positive Regulation Of Macrophage Differentiation Macromolecule Biosynthetic Process Mitotic Sister Chromatid Cohesion Enucleate Erythrocyte Differentiation Chromatin Silencing At RDNA Transcription Initiation From RNA Polymerase III Promoter Positive Regulation Of Chromosome Segregation Regulation Of Sister Chromatid Cohesion Hepatocyte Apoptotic Process Regulation Of Transcription Involved In G1/S Transition Of Mitotic Cell Cycle Viral Process Termination Of RNA Polymerase I Transcription Transcription Elongation From RNA Polymerase I Promoter Mitotic Metaphase Plate Congression Nucleobase-containing Compound Metabolic Process Transcription Initiation From RNA Polymerase I Promoter Protein Localization To Chromosome Chromatin Modification Neuron Maturation Sister Chromatid Cohesion Transcription From RNA Polymerase I Promoter Metaphase Plate Congression Negative Regulation Of Smoothened Signaling Pathway Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Chromatin Silencing Cellular Nitrogen Compound Metabolic Process	Regulation Of Receptor Recycling Endosome To Lysosome Transport Lysosomal Transport Vacuolar Transport Cytoplasmic Transport Endosomal Transport Receptor Internalization Involved In Canonical Wnt Signaling Pathway Negative Regulation Of Receptor Recycling 5S Class RRNA Transcription From RNA Polymerase III Type 1 Promoter TRNA Transcription From RNA Polymerase III Promoter Positive Regulation Of Clathrin-mediated Endocytosis Intracellular Transport TRNA Transcription Golgi Ribbon Formation Regulation Of Mitotic Spindle Assembly Regulation Of Spindle Assembly Regulation Of Clathrin-mediated Endocytosis Establishment Of Localization In Cell Regulation Of Mitotic Spindle Organization Cell Separation After Cytokinesis Positive Regulation Of Receptor Internalization Protein Targeting To Golgi RRNA Transcription Golgi To Plasma Membrane Protein Transport Cellular Localization Establishment Of Protein Localization To Golgi Retrograde Transport, Vesicle Recycling Within Golgi Mitotic Metaphase Plate Congression Mitotic Cell Cycle Process Regulation Of Receptor Internalization Metaphase Plate Congression Mitotic Cell Cycle Golgi To Plasma Membrane Transport Defense Response To Gram-negative Bacterium Positive Regulation Of Receptor-mediated Endocytosis Protein Localization To Golgi Apparatus Regulation Of Centrosome Duplication Receptor Internalization Establishment Of Chromosome Localization Membrane Organization Regulation Of Signaling Regulation Of Centrosome Cycle Transcription From RNA Polymerase III Promoter Negative Regulation Of I-kappaB Kinase/NF-kappaB Signaling Lysosome Organization Intra-Golgi Vesicle-mediated Transport Macroautophagy Cell Cycle Process Negative Regulation Of Signal Transduction Mitotic Sister Chromatid Segregation
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