GTF3A

Name	general transcription factor IIIA
Structure	No pdb structure
Interactors	5 interactors: APP CHMP5 GTF3C2 OPTN SCYL2
GO Annotations	Cellular Component	Nucleus Nucleoplasm
	Molecular Function	Nucleic Acid Binding DNA Binding RNA Binding 5S RRNA Binding Zinc Ion Binding Metal Ion Binding
	Biological Process	Transcription By RNA Polymerase III RRNA Transcription Ribosome Biogenesis Ribosomal Large Subunit Biogenesis
Pathways	RNA Polymerase III Abortive And Retractive Initiation RNA Polymerase III Transcription Initiation From Type 1 Promoter RNA Polymerase III Transcription Initiation From Type 1 Promoter
GWAS	Body mass index ( 20935630 ) Body size at age 10 ( 32376654 ) Night sleep phenotypes ( 27126917 )
Entrez ID	2971
HPRD ID	02916
Ensembl ID	ENSG00000122034
Uniprot IDs	Q92664
PDB IDs	Not available
GO Terms Enriched among Interactors ?	Endosome Regulation Of Receptor Recycling Amyloid-beta Complex Growth Cone Lamellipodium Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Toll Signaling Pathway Cellular Localization Vesicle-mediated Transport Defense Response To Gram-negative Bacterium Endosome To Lysosome Transport Acetylcholine Receptor Activator Activity Negative Regulation Of Canonical Wnt Signaling Pathway PTB Domain Binding Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Recycling Endosome Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Endothelin Production Growth Cone Filopodium Lipoprotein Particle Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Lysosomal Transport Vacuolar Transport Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Intermediate-density Lipoprotein Particle Negative Regulation Of Wnt Signaling Pathway Axon Midline Choice Point Recognition Positive Regulation Of Amyloid Fibril Formation Cellular Response To Norepinephrine Stimulus Cytoplasmic Vesicle Growth Factor Receptor Binding Main Axon Astrocyte Activation Involved In Immune Response Low-density Lipoprotein Particle Mediated Signaling Negative Regulation Of Receptor Recycling Type 2 Mitophagy Regulation Of Spontaneous Synaptic Transmission NMDA Selective Glutamate Receptor Signaling Pathway Regulation Of Synapse Structure Or Activity Regulation Of Toll Signaling Pathway Transcription Factor TFIIIC Complex 5S Class RRNA Transcription By RNA Polymerase III Regulation Of Canonical Wnt Signaling Pathway Axon Choice Point Recognition Pyramidal Neuron Development