GTF3A and SCYL2

Number of citations of the paper that reports this interaction (PubMedID 1589293)
0

Data Source:
HPRD (in vitro, in vivo)

		GTF3A	SCYL2
Description		general transcription factor IIIA	SCY1 like pseudokinase 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm	Endosome Golgi Apparatus Endosome Membrane Membrane Clathrin-coated Vesicle Cytoplasmic Vesicle
	Molecular Function	Nucleic Acid Binding DNA Binding RNA Binding 5S RRNA Binding Zinc Ion Binding Metal Ion Binding	Protein Kinase Activity Signaling Receptor Binding Protein Binding ATP Binding
	Biological Process	Transcription By RNA Polymerase III RRNA Transcription Ribosome Biogenesis Ribosomal Large Subunit Biogenesis	Brain Development Endosome To Lysosome Transport Pyramidal Neuron Development Receptor Internalization Clathrin-dependent Endocytosis Negative Regulation Of Canonical Wnt Signaling Pathway
Pathways		RNA Polymerase III Abortive And Retractive Initiation RNA Polymerase III Transcription Initiation From Type 1 Promoter RNA Polymerase III Transcription Initiation From Type 1 Promoter
Drugs
Diseases
GWAS		Body mass index ( 20935630) Body size at age 10 ( 32376654) Night sleep phenotypes ( 27126917)	Femur bone mineral density x serum urate levels interaction ( 34046847) Squamous cell carcinoma ( 23341777)
Interacting Genes		5 interacting genes: APP CHMP5 GTF3C2 OPTN SCYL2	4 interacting genes: CLTC GTF3A RBM11 ZFYVE9
Entrez ID		2971	55681
HPRD ID		02916	07642
Ensembl ID		ENSG00000122034	ENSG00000136021
Uniprot IDs		Q92664	A0A0U1RQQ9 Q6P3W7
PDB IDs
Enriched GO Terms of Interacting Partners?		Endosome Regulation Of Receptor Recycling Amyloid-beta Complex Growth Cone Lamellipodium Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Toll Signaling Pathway Cellular Localization Vesicle-mediated Transport Defense Response To Gram-negative Bacterium Endosome To Lysosome Transport Acetylcholine Receptor Activator Activity Negative Regulation Of Canonical Wnt Signaling Pathway PTB Domain Binding Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Recycling Endosome Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Endothelin Production Growth Cone Filopodium Lipoprotein Particle Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Lysosomal Transport Vacuolar Transport Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Intermediate-density Lipoprotein Particle Negative Regulation Of Wnt Signaling Pathway Axon Midline Choice Point Recognition Positive Regulation Of Amyloid Fibril Formation Cellular Response To Norepinephrine Stimulus Cytoplasmic Vesicle Growth Factor Receptor Binding Main Axon Astrocyte Activation Involved In Immune Response Low-density Lipoprotein Particle Mediated Signaling Negative Regulation Of Receptor Recycling Type 2 Mitophagy Regulation Of Spontaneous Synaptic Transmission NMDA Selective Glutamate Receptor Signaling Pathway Regulation Of Synapse Structure Or Activity Regulation Of Toll Signaling Pathway Transcription Factor TFIIIC Complex 5S Class RRNA Transcription By RNA Polymerase III Regulation Of Canonical Wnt Signaling Pathway Axon Choice Point Recognition Pyramidal Neuron Development	Clathrin Coat Of Trans-Golgi Network Vesicle Vesicle Uncoating Regulation Of Hyaluronan Biosynthetic Process Negative Regulation Of Hyaluronan Biosynthetic Process Clathrin Coat Clathrin Coat Of Coated Pit Endosomal Transport Clathrin Light Chain Binding Clathrin Coat Disassembly Amyloid-beta Clearance By Transcytosis Clathrin Complex Transferrin Transport RNA Binding 5S RRNA Binding 1-phosphatidylinositol Binding Transcytosis Endolysosome Membrane Endocytosis Ubiquitin-specific Protease Binding Mitotic Spindle Microtubule Clathrin Coat Assembly Clathrin-coated Endocytic Vesicle Low-density Lipoprotein Particle Receptor Binding Amyloid-beta Clearance Disordered Domain Specific Binding RRNA Transcription Poly(U) RNA Binding Nucleic Acid Binding Import Into Cell Negative Regulation Of Protein Localization To Plasma Membrane Clathrin-dependent Endocytosis Transcription By RNA Polymerase III Protein Depolymerization Ribosomal Large Subunit Biogenesis Regulation Of Mitotic Spindle Organization Iron Ion Transport Endosome Protein-containing Complex Single-stranded RNA Binding
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