GTF3A and SCYL2

Number of citations of the paper that reports this interaction (PMID 1589293)
0

Data Source:
HPRD (in vitro, in vivo)

		GTF3A	SCYL2
Gene Name		general transcription factor IIIA	SCY1-like 2 (S. cerevisiae)
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm	Golgi Apparatus Endosome Membrane Clathrin-coated Vesicle Perinuclear Region Of Cytoplasm
	Molecular Function	DNA Binding RNA Binding Metal Ion Binding	Protein Kinase Activity Receptor Binding Protein Binding ATP Binding
	Biological Process	Regulation Of Transcription, DNA-templated Transcription From RNA Polymerase III Promoter RRNA Transcription Gene Expression	Positive Regulation Of Receptor Internalization Protein Phosphorylation Endosome To Lysosome Transport Negative Regulation Of Canonical Wnt Signaling Pathway Receptor Internalization Involved In Canonical Wnt Signaling Pathway Positive Regulation Of Clathrin-mediated Endocytosis
Pathways		RNA Polymerase III Transcription Initiation RNA Polymerase III Transcription RNA Polymerase III Transcription Initiation From Type 1 Promoter RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription RNA Polymerase III Abortive And Retractive Initiation
Drugs
Diseases
GWAS		Body mass index ( 20935630)	Squamous cell carcinoma ( 23341777)
Protein-Protein Interactions		4 interactors: CHMP5 GTF3C2 OPTN SCYL2	3 interactors: CLTC GTF3A ZFYVE9
Entrez ID		2971	55681
HPRD ID		02916	07642
Ensembl ID		ENSG00000122034	ENSG00000136021
Uniprot IDs		Q92664	Q6P3W7
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Receptor Recycling Endosome To Lysosome Transport Lysosomal Transport Vacuolar Transport Cytoplasmic Transport Endosomal Transport Receptor Internalization Involved In Canonical Wnt Signaling Pathway Negative Regulation Of Receptor Recycling 5S Class RRNA Transcription From RNA Polymerase III Type 1 Promoter TRNA Transcription From RNA Polymerase III Promoter Positive Regulation Of Clathrin-mediated Endocytosis Intracellular Transport TRNA Transcription Golgi Ribbon Formation Regulation Of Mitotic Spindle Assembly Regulation Of Spindle Assembly Regulation Of Clathrin-mediated Endocytosis Establishment Of Localization In Cell Regulation Of Mitotic Spindle Organization Cell Separation After Cytokinesis Positive Regulation Of Receptor Internalization Protein Targeting To Golgi RRNA Transcription Golgi To Plasma Membrane Protein Transport Cellular Localization Establishment Of Protein Localization To Golgi Retrograde Transport, Vesicle Recycling Within Golgi Mitotic Metaphase Plate Congression Mitotic Cell Cycle Process Regulation Of Receptor Internalization Metaphase Plate Congression Mitotic Cell Cycle Golgi To Plasma Membrane Transport Defense Response To Gram-negative Bacterium Positive Regulation Of Receptor-mediated Endocytosis Protein Localization To Golgi Apparatus Regulation Of Centrosome Duplication Receptor Internalization Establishment Of Chromosome Localization Membrane Organization Regulation Of Signaling Regulation Of Centrosome Cycle Transcription From RNA Polymerase III Promoter Negative Regulation Of I-kappaB Kinase/NF-kappaB Signaling Lysosome Organization Intra-Golgi Vesicle-mediated Transport Macroautophagy Cell Cycle Process Negative Regulation Of Signal Transduction Mitotic Sister Chromatid Segregation	Negative Regulation Of Hyaluronan Biosynthetic Process SMAD Protein Import Into Nucleus
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