GTF3C1 and DEDD

Number of citations of the paper that reports this interaction (PMID 11965497)
8

Data Source:
HPRD (two hybrid, in vitro)

		GTF3C1	DEDD
Gene Name		general transcription factor IIIC, polypeptide 1, alpha 220kDa	death effector domain containing
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Transcription Factor TFIIIC Complex Nucleus Nucleoplasm Nucleolus Membrane Ribonucleoprotein Complex	Nucleolus Cytoplasm
	Molecular Function	DNA Binding Protein Binding	DNA Binding Protein Binding
	Biological Process	Transcription, DNA-templated Transcription From RNA Polymerase III Promoter RRNA Transcription TRNA Transcription Gene Expression 5S Class RRNA Transcription From RNA Polymerase III Type 1 Promoter TRNA Transcription From RNA Polymerase III Promoter	Transcription, DNA-templated Spermatogenesis Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Negative Regulation Of Protein Catabolic Process Regulation Of Apoptotic Process Decidualization Negative Regulation Of Transcription Of Nuclear Large RRNA Transcript From RNA Polymerase I Promoter
Pathways		RNA Polymerase III Transcription RNA Polymerase III Transcription Initiation RNA Polymerase III Transcription Initiation From Type 1 Promoter RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription RNA Polymerase III Abortive And Retractive Initiation RNA Polymerase III Transcription Initiation From Type 2 Promoter
Drugs
Diseases
GWAS
Protein-Protein Interactions		21 interactors: AGTRAP AKTIP ASCC2 CHN1 CMTM5 CPE CSNK1E DEDD EZH2 FGFR3 GTF3C4 HGH1 IGFBP3 KLF6 MAGEA4 MAPK10 NHP2L1 PRPF38A RBM23 SUPT5H TBC1D17	16 interactors: APLP2 APP BATF2 CASP10 CASP3 CASP8 CFLAR DEDD2 FADD GTF3C1 GTF3C3 HOXD4 KRT18 KRT8 SHMT1 SMAD3
Entrez ID		2975	9191
HPRD ID		07540	06022
Ensembl ID		ENSG00000077235	ENSG00000158796
Uniprot IDs		Q12789	B1AQP5 B4DKM1 O75618
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Metabolic Process Regulation Of Circadian Rhythm Negative Regulation Of DNA-templated Transcription, Elongation Positive Regulation Of Catalytic Activity Regulation Of Muscle Cell Differentiation MRNA Processing Positive Regulation Of MAPK Cascade Positive Regulation Of Signal Transduction Regulation Of Myoblast Differentiation Positive Regulation Of Phosphorylation Negative Regulation Of Muscle Cell Differentiation RNA Metabolic Process Positive Regulation Of Cellular Metabolic Process Fibroblast Growth Factor Receptor Apoptotic Signaling Pathway Regulation Of DNA-templated Transcription, Elongation MRNA Metabolic Process RNA Processing Cellular Nitrogen Compound Metabolic Process Gene Expression Cellular Metabolic Process Regulation Of MAPK Cascade Single Stranded Viral RNA Replication Via Double Stranded DNA Intermediate Regulation Of Protein Metabolic Process Regulation Of Protein Phosphorylation Positive Regulation Of Cellular Protein Metabolic Process Negative Regulation Of Transcription Of Nuclear Large RRNA Transcript From RNA Polymerase I Promoter Nucleobase-containing Compound Metabolic Process Regulation Of Intracellular Signal Transduction Regulation Of Catalytic Activity Nitrogen Compound Metabolic Process Positive Regulation Of Protein Phosphorylation Cell Surface Receptor Signaling Pathway Regulation Of Metabolic Process Positive Regulation Of Protein Metabolic Process Skeletal Muscle Satellite Cell Maintenance Involved In Skeletal Muscle Regeneration Regulation Of Gliogenesis Heterocycle Metabolic Process Extrinsic Apoptotic Signaling Pathway Cellular Aromatic Compound Metabolic Process Cellular Protein Modification Process Insulin Processing Regulation Of Phosphorylation Positive Regulation Of Intracellular Signal Transduction Alveolar Secondary Septum Development 5S Class RRNA Transcription From RNA Polymerase III Type 1 Promoter TRNA Transcription From RNA Polymerase III Promoter JUN Phosphorylation Positive Regulation Of Canonical Wnt Signaling Pathway Regulation Of Cellular Protein Metabolic Process Axonogenesis Involved In Innervation	Extrinsic Apoptotic Signaling Pathway Apoptotic Signaling Pathway Apoptotic Process Programmed Cell Death Cell Death Death Positive Regulation Of Peptidase Activity Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Regulation Of Endopeptidase Activity Activation Of Cysteine-type Endopeptidase Activity Regulation Of Peptidase Activity Zymogen Activation Positive Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Positive Regulation Of Cysteine-type Endopeptidase Activity Positive Regulation Of Endopeptidase Activity Positive Regulation Of Proteolysis Regulation Of Proteolysis Hepatocyte Apoptotic Process Regulation Of Necroptotic Process Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Regulation Of Cysteine-type Endopeptidase Activity Protein Processing Regulation Of Necrotic Cell Death Viral Process TRAIL-activated Apoptotic Signaling Pathway Response To Tumor Necrosis Factor Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Regulation Of Apoptotic Process Positive Regulation Of Cell Death Regulation Of Cell Death Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling 5S Class RRNA Transcription From RNA Polymerase III Type 1 Promoter TRNA Transcription From RNA Polymerase III Promoter Positive Regulation Of Apoptotic Signaling Pathway Neuron Apoptotic Process TRNA Transcription Regulation Of Extrinsic Apoptotic Signaling Pathway Cellular Component Disassembly Involved In Execution Phase Of Apoptosis Neuron Death Regulation Of I-kappaB Kinase/NF-kappaB Signaling Execution Phase Of Apoptosis Negative Regulation Of Programmed Cell Death Positive Regulation Of Extrinsic Apoptotic Signaling Pathway Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Negative Regulation Of Cell Death Positive Regulation Of Macrophage Differentiation Negative Regulation Of Necroptotic Process Positive Regulation Of Hydrolase Activity
Tagcloud ?			actinobacteria cleaving detectable distant divergent duplex equivalent exoribonuclease founding homology hundreds hypothetical kingdom maintain mediating orthologs overhangs pathogen phylogenetically pool prevalent proteobacteria reveals ribonucleases rnase rnases rv2179c similarity strand
Tagcloud (Difference) ?			actinobacteria cleaving detectable distant divergent duplex equivalent exoribonuclease founding homology hundreds hypothetical kingdom maintain mediating orthologs overhangs pathogen phylogenetically pool prevalent proteobacteria reveals ribonucleases rnase rnases rv2179c similarity strand
Tagcloud (Intersection) ?