GTF3C1 and HGH1

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		GTF3C1	HGH1
Gene Name		general transcription factor IIIC, polypeptide 1, alpha 220kDa	HGH1 homolog (S. cerevisiae)
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Transcription Factor TFIIIC Complex Nucleus Nucleoplasm Nucleolus Membrane Ribonucleoprotein Complex	Cellular_component
	Molecular Function	DNA Binding Protein Binding	Molecular_function
	Biological Process	Transcription, DNA-templated Transcription From RNA Polymerase III Promoter RRNA Transcription TRNA Transcription Gene Expression 5S Class RRNA Transcription From RNA Polymerase III Type 1 Promoter TRNA Transcription From RNA Polymerase III Promoter	Biological_process
Pathways		RNA Polymerase III Transcription RNA Polymerase III Transcription Initiation RNA Polymerase III Transcription Initiation From Type 1 Promoter RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription RNA Polymerase III Abortive And Retractive Initiation RNA Polymerase III Transcription Initiation From Type 2 Promoter
Drugs
Diseases
GWAS
Protein-Protein Interactions		21 interactors: AGTRAP AKTIP ASCC2 CHN1 CMTM5 CPE CSNK1E DEDD EZH2 FGFR3 GTF3C4 HGH1 IGFBP3 KLF6 MAGEA4 MAPK10 NHP2L1 PRPF38A RBM23 SUPT5H TBC1D17	9 interactors: APOM GPRASP1 GTF3C1 MED31 POLA2 PTN RPA1 TMEM256 TRIT1
Entrez ID		2975	51236
HPRD ID		07540	17423
Ensembl ID		ENSG00000077235	ENSG00000235173
Uniprot IDs		Q12789	Q9BTY7
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Metabolic Process Regulation Of Circadian Rhythm Negative Regulation Of DNA-templated Transcription, Elongation Positive Regulation Of Catalytic Activity Regulation Of Muscle Cell Differentiation MRNA Processing Positive Regulation Of MAPK Cascade Positive Regulation Of Signal Transduction Regulation Of Myoblast Differentiation Positive Regulation Of Phosphorylation Negative Regulation Of Muscle Cell Differentiation RNA Metabolic Process Positive Regulation Of Cellular Metabolic Process Fibroblast Growth Factor Receptor Apoptotic Signaling Pathway Regulation Of DNA-templated Transcription, Elongation MRNA Metabolic Process RNA Processing Cellular Nitrogen Compound Metabolic Process Gene Expression Cellular Metabolic Process Regulation Of MAPK Cascade Single Stranded Viral RNA Replication Via Double Stranded DNA Intermediate Regulation Of Protein Metabolic Process Regulation Of Protein Phosphorylation Positive Regulation Of Cellular Protein Metabolic Process Negative Regulation Of Transcription Of Nuclear Large RRNA Transcript From RNA Polymerase I Promoter Nucleobase-containing Compound Metabolic Process Regulation Of Intracellular Signal Transduction Regulation Of Catalytic Activity Nitrogen Compound Metabolic Process Positive Regulation Of Protein Phosphorylation Cell Surface Receptor Signaling Pathway Regulation Of Metabolic Process Positive Regulation Of Protein Metabolic Process Skeletal Muscle Satellite Cell Maintenance Involved In Skeletal Muscle Regeneration Regulation Of Gliogenesis Heterocycle Metabolic Process Extrinsic Apoptotic Signaling Pathway Cellular Aromatic Compound Metabolic Process Cellular Protein Modification Process Insulin Processing Regulation Of Phosphorylation Positive Regulation Of Intracellular Signal Transduction Alveolar Secondary Septum Development 5S Class RRNA Transcription From RNA Polymerase III Type 1 Promoter TRNA Transcription From RNA Polymerase III Promoter JUN Phosphorylation Positive Regulation Of Canonical Wnt Signaling Pathway Regulation Of Cellular Protein Metabolic Process Axonogenesis Involved In Innervation	Telomere Maintenance Via Semi-conservative Replication Nuclear DNA Replication Telomere Maintenance Via Recombination Mitotic Recombination DNA Strand Elongation Involved In DNA Replication DNA Strand Elongation Telomere Maintenance Via Telomere Lengthening Telomere Maintenance DNA-dependent DNA Replication G-protein Coupled Receptor Catabolic Process Negative Regulation Of Plasma Lipoprotein Particle Oxidation G1/S Transition Of Mitotic Cell Cycle DNA Recombinase Assembly 5S Class RRNA Transcription From RNA Polymerase III Type 1 Promoter TRNA Transcription From RNA Polymerase III Promoter High-density Lipoprotein Particle Clearance TRNA Transcription High-density Lipoprotein Particle Assembly Transmembrane Receptor Protein Tyrosine Phosphatase Signaling Pathway DNA Recombination Negative Regulation Of Lipoprotein Metabolic Process Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition DNA Replication Regulation Of Lipoprotein Metabolic Process Nucleotide-excision Repair, DNA Gap Filling High-density Lipoprotein Particle Remodeling Protein-lipid Complex Assembly Nucleotide-excision Repair, DNA Damage Removal Reverse Cholesterol Transport Receptor Catabolic Process RRNA Transcription Plasma Lipoprotein Particle Remodeling Cholesterol Efflux Protein Import Into Nucleus, Translocation Regulation Of Cellular Response To Heat
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