GTF2A2 and GTF2A1

Number of citations of the paper that reports this interaction (PMID 7958900)
38

Data Source:
BioGRID (two hybrid, pull down)
HPRD (in vitro)

		GTF2A2	GTF2A1
Gene Name		general transcription factor IIA, 2, 12kDa	general transcription factor IIA, 1, 19/37kDa
Image
Gene Ontology Annotations	Cellular Component	Nucleoplasm Transcription Factor TFIIA Complex Cell Junction	Nucleoplasm Transcription Factor TFIIA Complex Cytoplasm
	Molecular Function	RNA Polymerase II Repressing Transcription Factor Binding Transcription Coactivator Activity Protein Binding Transcription Factor Binding TBP-class Protein Binding Protein Homodimerization Activity Protein Heterodimerization Activity	DNA Binding Transcription Coactivator Activity Protein Binding Transcription Factor Binding TBP-class Protein Binding Protein Heterodimerization Activity
	Biological Process	Transcription From RNA Polymerase II Promoter Transcription Initiation From RNA Polymerase II Promoter Transcription Elongation From RNA Polymerase II Promoter Gene Expression Viral Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity RNA Polymerase II Transcriptional Preinitiation Complex Assembly	Regulation Of Transcription, DNA-templated Transcription From RNA Polymerase II Promoter Transcription Initiation From RNA Polymerase II Promoter Transcription Elongation From RNA Polymerase II Promoter Gene Expression Viral Process
Pathways		RNA Polymerase II Promoter Escape RNA Polymerase II Transcription Pre-Initiation And Promoter Opening RNA Polymerase II Transcription HIV Infection RNA Polymerase II Pre-transcription Events Late Phase of HIV Life Cycle HIV Life Cycle HIV Transcription Initiation RNA Polymerase II Transcription Initiation And Promoter Clearance RNA Polymerase II HIV Promoter Escape RNA Polymerase II Transcription Initiation Transcription of the HIV genome	RNA Polymerase II Promoter Escape RNA Polymerase II Transcription Pre-Initiation And Promoter Opening RNA Polymerase II Transcription HIV Infection RNA Polymerase II Pre-transcription Events Late Phase of HIV Life Cycle HIV Life Cycle HIV Transcription Initiation RNA Polymerase II Transcription Initiation And Promoter Clearance RNA Polymerase II HIV Promoter Escape RNA Polymerase II Transcription Initiation Transcription of the HIV genome
Drugs
Diseases
GWAS
Protein-Protein Interactions		7 interactors: GTF2A1 GTF2A1L GTF2E1 HSF1 TAF4 TBP TBPL1	18 interactors: BCL3 CREB1 CSNK2A1 CSNK2A2 GTF2A2 GTF2E1 GTF2E2 GTF2F1 HMGB1 NCOA6 NFYA TAF1 TAF4 TAF4B TASP1 TBP TBPL1 TRIP4
Entrez ID		2958	2957
HPRD ID		02747	02748
Ensembl ID		ENSG00000140307	ENSG00000165417
Uniprot IDs		B2R506 P52657	P52655
PDB IDs		1NVP	1NVP
Enriched GO Terms of Interacting Partners?		DNA-templated Transcription, Initiation Transcription From RNA Polymerase II Promoter Transcription Initiation From RNA Polymerase II Promoter Transcription Elongation From RNA Polymerase II Promoter DNA-templated Transcription, Elongation Transcription, DNA-templated RNA Biosynthetic Process RNA Metabolic Process Gene Expression Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Viral Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Multicellular Organismal Reproductive Process Multicellular Organism Reproduction Reproduction Single Organism Reproductive Process Reproductive Process Spermatogenesis Male Gamete Generation Regulation Of Metabolic Process Gamete Generation Developmental Process Involved In Reproduction DTTP Biosynthetic Process Sexual Reproduction Cellular Metabolic Process Embryonic Process Involved In Female Pregnancy Deoxyribonucleotide Biosynthetic Process Acrosome Assembly Chromatin Silencing At RDNA Positive Regulation Of Transcription, DNA-templated Regulation Of Spindle Checkpoint Deoxyribonucleoside Triphosphate Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Termination Of RNA Polymerase I Transcription Positive Regulation Of Gene Expression Transcription Elongation From RNA Polymerase I Promoter Spermatid Nucleus Differentiation Regulation Of Cellular Process	Transcription Elongation From RNA Polymerase II Promoter DNA-templated Transcription, Initiation DNA-templated Transcription, Elongation Transcription Initiation From RNA Polymerase II Promoter Transcription From RNA Polymerase II Promoter Transcription, DNA-templated RNA Biosynthetic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process RNA Metabolic Process Gene Expression Cellular Macromolecule Biosynthetic Process Positive Regulation Of Transcription, DNA-templated Nucleobase-containing Compound Metabolic Process Macromolecule Biosynthetic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Cellular Nitrogen Compound Metabolic Process Positive Regulation Of Gene Expression Viral Process Positive Regulation Of Cellular Biosynthetic Process Nitrogen Compound Metabolic Process Biosynthetic Process Regulation Of Metabolic Process Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Metabolic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter RNA Polymerase II Transcriptional Preinitiation Complex Assembly Regulation Of Cellular Process Cellular Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Metabolic Process Rhythmic Process Intracellular Estrogen Receptor Signaling Pathway Regulation Of DNA-templated Transcription, Initiation Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Secretory Granule Organization Regulation Of Proteasomal Protein Catabolic Process Mitotic Spindle Checkpoint Negative Regulation Of Chromosome Segregation Regulation Of Mitotic Sister Chromatid Separation Negative Regulation Of Mitotic Nuclear Division Spindle Checkpoint Regulation Of Mitotic Metaphase/anaphase Transition Negative Regulation Of Apoptotic Cell Clearance
Tagcloud ?		advance atp5j differs doi erythroleukemia exerts lep lim lipoma lpp m133k march mpn neoplasm npy1r npy5r onc online persistently platelets preferred promoters publication recruit stat5 synergistically thrombopoietin transducer vegfc
Tagcloud (Difference) ?		advance atp5j differs doi erythroleukemia exerts lep lim lipoma lpp m133k march mpn neoplasm npy1r npy5r onc online persistently platelets preferred promoters publication recruit stat5 synergistically thrombopoietin transducer vegfc
Tagcloud (Intersection) ?