GTF2A2 and TAF4

Number of citations of the paper that reports this interaction (PMID 11564872)
23

Data Source:
HPRD (in vitro)

		GTF2A2	TAF4
Gene Name		general transcription factor IIA, 2, 12kDa	TAF4 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 135kDa
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Gene Ontology Annotations	Cellular Component	Nucleoplasm Transcription Factor TFIIA Complex Cell Junction	Nucleoplasm Transcription Factor TFIID Complex Cytoplasm Transcription Factor TFTC Complex MLL1 Complex
	Molecular Function	RNA Polymerase II Repressing Transcription Factor Binding Transcription Coactivator Activity Protein Binding Transcription Factor Binding TBP-class Protein Binding Protein Homodimerization Activity Protein Heterodimerization Activity	DNA Binding Sequence-specific DNA Binding Transcription Factor Activity Transcription Coactivator Activity Protein Binding Protein Heterodimerization Activity
	Biological Process	Transcription From RNA Polymerase II Promoter Transcription Initiation From RNA Polymerase II Promoter Transcription Elongation From RNA Polymerase II Promoter Gene Expression Viral Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity RNA Polymerase II Transcriptional Preinitiation Complex Assembly	Ovarian Follicle Development DNA-templated Transcription, Initiation Transcription From RNA Polymerase II Promoter Transcription Initiation From RNA Polymerase II Promoter Transcription Elongation From RNA Polymerase II Promoter Gene Expression Viral Process Positive Regulation Of Transcription, DNA-templated
Pathways		RNA Polymerase II Promoter Escape RNA Polymerase II Transcription Pre-Initiation And Promoter Opening RNA Polymerase II Transcription HIV Infection RNA Polymerase II Pre-transcription Events Late Phase of HIV Life Cycle HIV Life Cycle HIV Transcription Initiation RNA Polymerase II Transcription Initiation And Promoter Clearance RNA Polymerase II HIV Promoter Escape RNA Polymerase II Transcription Initiation Transcription of the HIV genome	RNA Polymerase II Promoter Escape RNA Polymerase II Transcription Pre-Initiation And Promoter Opening RNA Polymerase II Transcription HIV Infection RNA Polymerase II Pre-transcription Events Late Phase of HIV Life Cycle HIV Life Cycle HIV Transcription Initiation RNA Polymerase II Transcription Initiation And Promoter Clearance RNA Polymerase II HIV Promoter Escape RNA Polymerase II Transcription Initiation Transcription of the HIV genome
Drugs
Diseases
GWAS
Protein-Protein Interactions		7 interactors: GTF2A1 GTF2A1L GTF2E1 HSF1 TAF4 TBP TBPL1	22 interactors: AHR ATF7 CBX3 CBX5 CREM GTF2A1 GTF2A2 HIST3H3 HTT JUN SP1 TAF1 TAF10 TAF11 TAF12 TAF2 TAF5 TAF6 TAF7 TAF8 TAF9 TCF12
Entrez ID		2958	6874
HPRD ID		02747	11797
Ensembl ID		ENSG00000140307	ENSG00000130699
Uniprot IDs		B2R506 P52657	O00268
PDB IDs		1NVP	1H3O 2P6V
Enriched GO Terms of Interacting Partners?		DNA-templated Transcription, Initiation Transcription From RNA Polymerase II Promoter Transcription Initiation From RNA Polymerase II Promoter Transcription Elongation From RNA Polymerase II Promoter DNA-templated Transcription, Elongation Transcription, DNA-templated RNA Biosynthetic Process RNA Metabolic Process Gene Expression Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Viral Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Multicellular Organismal Reproductive Process Multicellular Organism Reproduction Reproduction Single Organism Reproductive Process Reproductive Process Spermatogenesis Male Gamete Generation Regulation Of Metabolic Process Gamete Generation Developmental Process Involved In Reproduction DTTP Biosynthetic Process Sexual Reproduction Cellular Metabolic Process Embryonic Process Involved In Female Pregnancy Deoxyribonucleotide Biosynthetic Process Acrosome Assembly Chromatin Silencing At RDNA Positive Regulation Of Transcription, DNA-templated Regulation Of Spindle Checkpoint Deoxyribonucleoside Triphosphate Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Termination Of RNA Polymerase I Transcription Positive Regulation Of Gene Expression Transcription Elongation From RNA Polymerase I Promoter Spermatid Nucleus Differentiation Regulation Of Cellular Process	Transcription Elongation From RNA Polymerase II Promoter Transcription Initiation From RNA Polymerase II Promoter DNA-templated Transcription, Elongation DNA-templated Transcription, Initiation Transcription From RNA Polymerase II Promoter Transcription, DNA-templated RNA Biosynthetic Process Viral Process RNA Metabolic Process Heterocycle Metabolic Process Regulation Of Gene Expression Gene Expression Cellular Nitrogen Compound Metabolic Process Regulation Of Transcription, DNA-templated Cellular Macromolecule Biosynthetic Process Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Macromolecule Biosynthetic Process Regulation Of RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Nitrogen Compound Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Regulation Of Nitrogen Compound Metabolic Process Positive Regulation Of Gene Expression Regulation Of Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Cellular Biosynthetic Process Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription From RNA Polymerase II Promoter Histone Acetylation Internal Peptidyl-lysine Acetylation Peptidyl-lysine Acetylation Positive Regulation By Host Of Viral Transcription Internal Protein Amino Acid Acetylation Protein Acetylation Regulation Of Transcription From RNA Polymerase II Promoter Cellular Metabolic Process Rhythmic Process Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Metabolic Process RNA Polymerase II Transcriptional Preinitiation Complex Assembly Peptidyl-lysine Modification Interaction With Symbiont Regulation Of Cellular Process Histone H3 Acetylation Positive Regulation Of Viral Transcription Chromatin Modification Circadian Rhythm Chromosome Organization
Tagcloud ?		advance atp5j differs doi erythroleukemia exerts lep lim lipoma lpp m133k march mpn neoplasm npy1r npy5r onc online persistently platelets preferred promoters publication recruit stat5 synergistically thrombopoietin transducer vegfc	adjacent characterised directed directing elements embryonic hepatocyte heterodimer highlighting hnf4a inactivation instructive interacts maintain maturation mutually natal occupancy pausing pic post promotes proximal start subset taf12 tafs tfiid
Tagcloud (Difference) ?		advance atp5j differs doi erythroleukemia exerts lep lim lipoma lpp m133k march mpn neoplasm npy1r npy5r onc online persistently platelets preferred promoters publication recruit stat5 synergistically thrombopoietin transducer vegfc	adjacent characterised directed directing elements embryonic hepatocyte heterodimer highlighting hnf4a inactivation instructive interacts maintain maturation mutually natal occupancy pausing pic post promotes proximal start subset taf12 tafs tfiid
Tagcloud (Intersection) ?