GSTZ1 and ZMYND12

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		GSTZ1	ZMYND12
Description		glutathione S-transferase zeta 1	zinc finger MYND-type containing 12
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GO Annotations	Cellular Component	Cytoplasm Mitochondrion Mitochondrial Matrix Cytosol	Cilium Motile Cilium Sperm Flagellum Cell Projection
	Molecular Function	Catalytic Activity Glutathione Transferase Activity Glutathione Peroxidase Activity Protein Binding Maleylacetoacetate Isomerase Activity Transferase Activity Isomerase Activity Identical Protein Binding Protein Homodimerization Activity	Protein Binding Zinc Ion Binding Metal Ion Binding
	Biological Process	L-phenylalanine Catabolic Process L-tyrosine Catabolic Process Glutathione Metabolic Process Aromatic Amino Acid Metabolic Process Cellular Oxidant Detoxification Cellular Detoxification	Sperm Axoneme Assembly Flagellated Sperm Motility
Pathways		Glutathione conjugation Regulation of pyruvate dehydrogenase (PDH) complex Tyrosine catabolism
Drugs		Glutathione 1,4-Dithiothreitol Dichloroacetic acid Glycerin
Diseases
GWAS
Interacting Genes		10 interacting genes: CLVS2 CRYAA GORASP2 GSS PLEKHG4 PPP1CC QARS1 TCP11 TRAF2 ZMYND12	80 interacting genes: ABI2 AIRIM ARHGAP8 ARMC8 ATOSB BMAL1 CCDC116 CCDC24 CHCHD2 CWF19L2 DMRT3 EVX2 FAM222B FAM50B FAM90A1 GPKOW GSTZ1 HAPLN2 HDAC4 HOXB5 HOXC9 HR HSF4 ILF2 INCA1 KANK2 LENG1 LMO2 LMO4 MAD2L2 MNS1 MOAP1 MSGN1 MSRB3 NAB2 NUDT22 ONECUT3 PATL1 PICK1 POM121 POU6F2 PPP1R18 PRKAA2 PRR35 PRR5-ARHGAP8 PRR5L PSMB8 QARS1 RIPPLY1 RUSC1 SAMD11 SAXO1 SAXO4 SCNM1 SDCBP SEC14L4 SH2D4A SHC3 SMARCD1 SMG9 SOHLH1 SPG21 STRA8 TEKT4 TEKT5 TEPSIN TFAP2D THOC1 THRSP TLE5 TSEN54 TSSK3 TTC29 TXN2 TYMP UNC5CL VEZF1 VPS37C ZNF148 ZNF414
Entrez ID		2954	84217
HPRD ID		04785	15740
Ensembl ID		ENSG00000100577	ENSG00000066185
Uniprot IDs		A0A0A0MR33 A0A0C4DFM0 G3V4T6 O43708	B4DX70 Q9H0C1
PDB IDs		1FW1 8E8P	8J07
Enriched GO Terms of Interacting Partners?			Protein Binding Sperm Flagellum Axonemal A Tubule Inner Sheath Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Transcription By RNA Polymerase II Motile Cilium Regulation Of RNA Metabolic Process Nucleus Chromatin Regulation Of Nucleobase-containing Compound Metabolic Process DNA-binding Transcription Factor Activity Transcription Coregulator Activity
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