ANKRD11 and RAC3

Number of citations of the paper that reports this interaction (PMID 15184363)
15

Data Source:
HPRD (two hybrid, in vitro)

		ANKRD11	RAC3
Gene Name		ankyrin repeat domain 11	ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Plasma Membrane	Cytosol Plasma Membrane Endomembrane System Lamellipodium Growth Cone Filamentous Actin Neuron Projection Neuronal Cell Body Perinuclear Region Of Cytoplasm Extracellular Vesicular Exosome Cell Periphery
	Molecular Function		GTPase Activity Protein Binding GTP Binding Calcium-dependent Protein Binding
	Biological Process	In Utero Embryonic Development Tissue Homeostasis Multicellular Organism Growth Odontogenesis Of Dentin-containing Tooth Skeletal System Morphogenesis Face Morphogenesis Bone Development	Small GTPase Mediated Signal Transduction Metabolic Process Cell Projection Assembly Actin Cytoskeleton Organization Neuron Projection Development Positive Regulation Of Cell Adhesion Mediated By Integrin Intracellular Signal Transduction Neuromuscular Process Controlling Balance Regulation Of Small GTPase Mediated Signal Transduction Positive Regulation Of Substrate Adhesion-dependent Cell Spreading
Pathways			Rho GTPase cycle Signaling by Rho GTPases Signaling by Wnt PCP/CE pathway beta-catenin independent WNT signaling
Drugs
Diseases
GWAS
Protein-Protein Interactions		19 interactors: BZRAP1 CDCA7L CEP44 GOLGA2 HDAC3 HDAC4 HDAC5 HOOK2 IKZF1 LZTS2 MKRN3 NCOA2 NCOA3 PDE4DIP RAC3 SRC TFIP11 TRAF2 TRIM37	9 interactors: ANKRD11 AR ARHGDIA ARHGDIB CIB1 ESR1 HNF1A NRBP1 RARA
Entrez ID		29123	5881
HPRD ID		12456	03629
Ensembl ID		ENSG00000167522	ENSG00000169750
Uniprot IDs		Q6UB99	P60763
PDB IDs			2C2H 2G0N 2IC5 2OV2 2QME
Enriched GO Terms of Interacting Partners?		Chromatin Modification Histone Modification Chromatin Organization Regulation Of Protein Binding Chromosome Organization Histone H4 Deacetylation Regulation Of Binding Positive Regulation Of Transcription, DNA-templated Histone H3 Deacetylation Histone H3-K9 Modification Organelle Organization Positive Regulation Of Receptor Activity Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of Transcription, DNA-templated Positive Regulation Of Gene Expression Receptor Transactivation Branching Involved In Mammary Gland Duct Morphogenesis Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of Transcription, DNA-templated Regulation Of RNA Biosynthetic Process Positive Regulation Of Cellular Biosynthetic Process Negative Regulation Of Nucleic Acid-templated Transcription Mammary Gland Branching Involved In Thelarche Negative Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Intracellular Receptor Signaling Pathway Histone Deacetylation Negative Regulation Of Transcription From RNA Polymerase II Promoter Mammary Gland Duct Morphogenesis Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Protein Deacetylation Intracellular Steroid Hormone Receptor Signaling Pathway Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Gene Expression Regulation Of Gene Expression Cellular Protein Modification Process Negative Regulation Of Biosynthetic Process Regulation Of Nitrogen Compound Metabolic Process Development Of Secondary Female Sexual Characteristics Peptidyl-lysine Modification Mammary Gland Morphogenesis Positive Regulation Of Cellular Metabolic Process Negative Regulation Of Myotube Differentiation Development Of Secondary Sexual Characteristics Cellular Response To Hormone Stimulus Mammary Gland Epithelium Development B Cell Differentiation Regulation Of Skeletal Muscle Fiber Development Vagina Development	Transcription Initiation From RNA Polymerase II Promoter DNA-templated Transcription, Initiation Prostate Gland Development Intracellular Steroid Hormone Receptor Signaling Pathway Developmental Process Involved In Reproduction Steroid Hormone Mediated Signaling Pathway Transcription From RNA Polymerase II Promoter Regulation Of Signal Transduction Hormone-mediated Signaling Pathway Regulation Of Signaling Multicellular Organismal Development Intracellular Estrogen Receptor Signaling Pathway Growth Gland Development Reproductive Structure Development Reproductive System Development Cellular Response To Steroid Hormone Stimulus Single Organism Reproductive Process Positive Regulation Of Metabolic Process Intracellular Receptor Signaling Pathway Cellular Response To Estrogen Stimulus Regulation Of Cell Adhesion Reproductive Process Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Developmental Process Regulation Of Apoptotic Process Response To Organic Substance Regulation Of Establishment Of Protein Localization To Plasma Membrane Regulation Of Cell Death System Development Regulation Of Protein Localization Sex Differentiation Positive Regulation Of Cell Proliferation Face Development Regulation Of Protein Localization To Plasma Membrane Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Regulation Of Intracellular Signal Transduction Rho Protein Signal Transduction Negative Regulation Of Apoptotic Process Organ Development Negative Regulation Of Programmed Cell Death Cellular Response To Organic Substance Negative Regulation Of Cell Death Urogenital System Development Organ Morphogenesis Cellular Response To Organic Cyclic Compound Positive Regulation Of Transcription From RNA Polymerase II Promoter Anatomical Structure Development Negative Regulation Of Integrin Biosynthetic Process Positive Regulation Of Male Germ Cell Proliferation
Tagcloud ?		12q13 1p36 cdls cleaves cohesin cornelia deeper discriminating encompassing espl1 exome filtering hdac8 intellectual intronic kbg lange merits mosaic multisystem nipbl novo partitioning rad21 recursive separase smc1a smc3 undetected	accessible acetyltransferases aspects cloned coactivator concert condensed cor corepressor corepressors deacetylases entry era establish extensively generate hormone initiate modulate replaced repressed repression smrt src1 steroid theme tif2 transcriptionally unliganded
Tagcloud (Difference) ?		12q13 1p36 cdls cleaves cohesin cornelia deeper discriminating encompassing espl1 exome filtering hdac8 intellectual intronic kbg lange merits mosaic multisystem nipbl novo partitioning rad21 recursive separase smc1a smc3 undetected	accessible acetyltransferases aspects cloned coactivator concert condensed cor corepressor corepressors deacetylases entry era establish extensively generate hormone initiate modulate replaced repressed repression smrt src1 steroid theme tif2 transcriptionally unliganded
Tagcloud (Intersection) ?