ANKRD11 and NCOA3

Number of citations of the paper that reports this interaction (PMID 15184363)
15

Data Source:
BioGRID (pull down)

		ANKRD11	NCOA3
Gene Name		ankyrin repeat domain 11	nuclear receptor coactivator 3
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Plasma Membrane	Nucleus Nucleoplasm Cytoplasm Extracellular Vesicular Exosome
	Molecular Function		Chromatin Binding Transcription Coactivator Activity Histone Acetyltransferase Activity Signal Transducer Activity Protein Binding Ligand-dependent Nuclear Receptor Binding Ligand-dependent Nuclear Receptor Transcription Coactivator Activity Nuclear Hormone Receptor Binding Thyroid Hormone Receptor Binding Protein Dimerization Activity Protein N-terminus Binding Androgen Receptor Binding
	Biological Process	In Utero Embryonic Development Tissue Homeostasis Multicellular Organism Growth Odontogenesis Of Dentin-containing Tooth Skeletal System Morphogenesis Face Morphogenesis Bone Development	Transcription, DNA-templated Positive Regulation Of Gene Expression Histone Acetylation Androgen Receptor Signaling Pathway Intracellular Receptor Signaling Pathway Cellular Response To Hormone Stimulus Multicellular Organism Growth Receptor Transactivation Positive Regulation Of Keratinocyte Differentiation Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription From RNA Polymerase II Promoter Developmental Growth Vagina Development Labyrinthine Layer Morphogenesis Mammary Gland Branching Involved In Thelarche Regulation Of RNA Biosynthetic Process
Pathways			PPARA activates gene expression Fatty acid, triacylglycerol, and ketone body metabolism Metabolism of lipids and lipoproteins Transcriptional regulation of white adipocyte differentiation Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha)
Drugs
Diseases
GWAS			Response to treatment for acute lymphoblastic leukemia ( 19176441)
Protein-Protein Interactions		19 interactors: BZRAP1 CDCA7L CEP44 GOLGA2 HDAC3 HDAC4 HDAC5 HOOK2 IKZF1 LZTS2 MKRN3 NCOA2 NCOA3 PDE4DIP RAC3 SRC TFIP11 TRAF2 TRIM37	77 interactors: ABL1 ANKRD11 AR ARNT2 ATAD2 BMP6 BMP7 BRCA1 BRE CCND1 CDKN3 CHUK CREBBP CSNK1E DCTN6 DDX17 DDX5 E2F1 EP300 ESR1 ESR2 ESRRA ESRRB ETV1 FOS GSK3B GTF2B HIST3H3 HIST4H4 IKBKB IKBKG IQCK JUN KAT2B MAPK1 MAPK14 MAPK8 MMS19 MN1 NCOR1 NCOR2 NKX2-1 NPAS2 NR0B2 NR1H2 NR1H3 NR1I2 NR1I3 NR2F1 NR3C1 NR4A1 NR5A2 PGR PIN1 PPARA PPARD PPARG PRKCZ PRMT1 PSMB9 PSME3 RARA RARB RARG RELA RXRA RXRB SMARCE1 SUFU SUMO1 TBP THRB TP53 TP53BP1 VDR YWHAH YWHAQ
Entrez ID		29123	8202
HPRD ID		12456	03570
Ensembl ID		ENSG00000167522	ENSG00000124151
Uniprot IDs		Q6UB99	Q0IIN7 Q59EE8 Q9Y6Q9
PDB IDs			1KBH 3L3X 3L3Z
Enriched GO Terms of Interacting Partners?		Chromatin Modification Histone Modification Chromatin Organization Regulation Of Protein Binding Chromosome Organization Histone H4 Deacetylation Regulation Of Binding Positive Regulation Of Transcription, DNA-templated Histone H3 Deacetylation Histone H3-K9 Modification Organelle Organization Positive Regulation Of Receptor Activity Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of Transcription, DNA-templated Positive Regulation Of Gene Expression Receptor Transactivation Branching Involved In Mammary Gland Duct Morphogenesis Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of Transcription, DNA-templated Regulation Of RNA Biosynthetic Process Positive Regulation Of Cellular Biosynthetic Process Negative Regulation Of Nucleic Acid-templated Transcription Mammary Gland Branching Involved In Thelarche Negative Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Intracellular Receptor Signaling Pathway Histone Deacetylation Negative Regulation Of Transcription From RNA Polymerase II Promoter Mammary Gland Duct Morphogenesis Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Protein Deacetylation Intracellular Steroid Hormone Receptor Signaling Pathway Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Gene Expression Regulation Of Gene Expression Cellular Protein Modification Process Negative Regulation Of Biosynthetic Process Regulation Of Nitrogen Compound Metabolic Process Development Of Secondary Female Sexual Characteristics Peptidyl-lysine Modification Mammary Gland Morphogenesis Positive Regulation Of Cellular Metabolic Process Negative Regulation Of Myotube Differentiation Development Of Secondary Sexual Characteristics Cellular Response To Hormone Stimulus Mammary Gland Epithelium Development B Cell Differentiation Regulation Of Skeletal Muscle Fiber Development Vagina Development	Steroid Hormone Mediated Signaling Pathway Transcription Initiation From RNA Polymerase II Promoter Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Gene Expression Intracellular Receptor Signaling Pathway Positive Regulation Of Cellular Metabolic Process Hormone-mediated Signaling Pathway Positive Regulation Of Macromolecule Biosynthetic Process DNA-templated Transcription, Initiation Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Cellular Biosynthetic Process Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Metabolic Process Response To Steroid Hormone Response To Lipid Regulation Of Nitrogen Compound Metabolic Process Cellular Response To Steroid Hormone Stimulus Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Cellular Response To Lipid Regulation Of Gene Expression Response To Hormone Transcription From RNA Polymerase II Promoter Response To Organic Cyclic Compound Cellular Response To Organic Cyclic Compound Cellular Response To Organic Substance Transcription, DNA-templated Response To Organic Substance RNA Biosynthetic Process Regulation Of Metabolic Process Cellular Response To Hormone Stimulus Signal Transduction Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of Gene Expression Gene Expression Negative Regulation Of RNA Biosynthetic Process Signaling Negative Regulation Of Biosynthetic Process Negative Regulation Of Cellular Metabolic Process Cell Communication Cellular Nitrogen Compound Metabolic Process Nucleobase-containing Compound Metabolic Process RNA Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Nitrogen Compound Metabolic Process Cellular Macromolecule Biosynthetic Process
Tagcloud ?		12q13 1p36 cdls cleaves cohesin cornelia deeper discriminating encompassing espl1 exome filtering hdac8 intellectual intronic kbg lange merits mosaic multisystem nipbl novo partitioning rad21 recursive separase smc1a smc3 undetected	acetyltransferase aggressive characteristically emu fusing haploinsufficient hence homeobox hox includes kat6a localizes lymphoma maintain maintaining maintains malignancy meis1 menin mll1 moz myst3 overlap progenitor progenitors proliferative tale tif2 translocations
Tagcloud (Difference) ?		12q13 1p36 cdls cleaves cohesin cornelia deeper discriminating encompassing espl1 exome filtering hdac8 intellectual intronic kbg lange merits mosaic multisystem nipbl novo partitioning rad21 recursive separase smc1a smc3 undetected	acetyltransferase aggressive characteristically emu fusing haploinsufficient hence homeobox hox includes kat6a localizes lymphoma maintain maintaining maintains malignancy meis1 menin mll1 moz myst3 overlap progenitor progenitors proliferative tale tif2 translocations
Tagcloud (Intersection) ?