CTNNA3 and ZNF474

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		CTNNA3	ZNF474
Description		catenin alpha 3	zinc finger protein 474
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytoskeleton Adherens Junction Fascia Adherens Lamellipodium Desmosome Anchoring Junction
	Molecular Function	Protein Binding Beta-catenin Binding Cadherin Binding Actin Filament Binding	Protein Binding Zinc Ion Binding Metal Ion Binding
	Biological Process	Cell Adhesion Cell Migration Bundle Of His Cell-Purkinje Myocyte Adhesion Involved In Cell Communication Regulation Of Heart Rate By Cardiac Conduction Cell-cell Adhesion Regulation Of Ventricular Cardiac Muscle Cell Action Potential
Pathways
Drugs
Diseases
GWAS		Adventurousness ( 30643258) Adverse response to drug ( 30420678) Asthma (toluene diisocyanate-induced) ( 19187332) Bronchopulmonary dysplasia ( 23897914) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Dental caries ( 23064961) Diffusing capacity of carbon monoxide ( 30694715) Docetaxel-induced peripheral neuropathy in metastatic castrate-resistant prostate cancer ( 27143689) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Epstein-Barr virus copy number in lymphoblastoid cell lines ( 28654678) Essential tremor ( 27797806) General risk tolerance (MTAG) ( 30643258) Household income (MTAG) ( 31844048) Lung function (FVC) ( 24023788) Metabolite levels ( 23823483) Metabolite levels (Pyroglutamine) ( 23934736) Mitochondrial DNA copy number ( 30704525) Nickel levels ( 26025379) Nicotine dependence ( 17158188) Night sleep phenotypes ( 27126917) Obesity-related traits ( 23251661) Optic disc area ( 28073927) Psoriatic arthritis ( 26626624) Pulse pressure ( 27841878) Rheumatic heart disease ( 34106200) Schizophrenia (cytomegalovirus infection interaction) ( 23358160) Subcutaneous adipose tissue ( 29178545) Systemic lupus erythematosus ( 28714469) Systolic blood pressure ( 27841878)	Intraocular pressure ( 29617998)
Interacting Genes		67 interacting genes: AKAP9 ATP23 BLOC1S2 C17orf50 CCDC183 CCDC33 CDSN CENPS-CORT CKMT1A CKMT1B CMC2 COG4 CRX CTNNB1 DISC1 ECSIT EID2B EPS8 FAM110A FAM161A FAM161B FAM9A FBXO28 FERD3L GINS3 GNB1 HDX HOMEZ JUP KATNAL1 LASP1 MARCHF7 MBD3L1 MSRA MYOG NAB2 NDUFB7 OIP5 ORC2 PAX6 PLAGL2 PNMA1 PNMA5 POU6F2 PPARA PRR5 REL RIPPLY1 RPS6KA5 SERTAD2 SPATS1 STMN2 TASOR2 TLX3 TNNI1 TNNI2 TRIM54 TXNRD3 USHBP1 VIP ZG16 ZNF19 ZNF426 ZNF474 ZNF552 ZNF620 ZNF662	29 interacting genes: ABI2 ATP6V0D2 BANP CABP5 CATSPERT CCDC57 COMMD8 CPNE7 CTNNA3 FRMD8 GPATCH11 GRB2 GYS1 IL16 KCTD7 MCMBP MLH1 NOXA1 PFKFB1 PPL PRKAB2 RSPH14 SEPHS1 TCF19 TEKT4 TRIM23 TSR2 UBASH3A ZIC1
Entrez ID		29119	133923
HPRD ID		09639	13411
Ensembl ID		ENSG00000183230	ENSG00000164185
Uniprot IDs		A8K141 Q8WW10 Q9UI47	Q6S9Z5
PDB IDs
Enriched GO Terms of Interacting Partners?		Protein Binding Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Catenin-TCF7L2 Complex Regulation Of RNA Metabolic Process Phosphocreatine Biosynthetic Process Creatine Kinase Activity DNA-binding Transcription Activator Activity Regulation Of Transcription By RNA Polymerase II Cellular Response To Indole-3-methanol Response To Indole-3-methanol Positive Regulation Of Neuroblast Proliferation
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