CTNNA3

Gene Name		catenin (cadherin-associated protein), alpha 3
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Cytoskeleton Fascia Adherens Lamellipodium
	Molecular Function	Protein Binding Cadherin Binding Actin Filament Binding
	Biological Process	Single Organismal Cell-cell Adhesion
Pathways
Drugs
Diseases
GWAS		Asthma (toluene diisocyanate-induced) ( 19187332) Dental caries ( 23064961) Nicotine dependence ( 17158188) Obesity-related traits ( 23251661) Schizophrenia (cytomegalovirus infection interaction) ( 23358160)
Protein-protein Interactions		2 interactors: CTNNB1 EPS8
Entrez ID		29119
HPRD ID		09639
Ensembl ID		ENSG00000183230
Uniprot IDs		A8K141 Q9UI47
PDB IDs
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Mitotic Cell Cycle, Embryonic Positive Regulation Of Epithelial Cell Proliferation Involved In Prostate Gland Development Schwann Cell Proliferation Cellular Response To Insulin-like Growth Factor Stimulus Canonical Wnt Signaling Pathway Involved In Positive Regulation Of Epithelial To Mesenchymal Transition Regulation Of Protein Complex Assembly Positive Regulation Of Heparan Sulfate Proteoglycan Biosynthetic Process Canonical Wnt Signaling Pathway Involved In Positive Regulation Of Cardiac Outflow Tract Cell Proliferation Actin Polymerization-dependent Cell Motility Renal Inner Medulla Development Renal Outer Medulla Development Mesenchymal Cell Proliferation Involved In Lung Development Glial Cell Fate Determination Oviduct Development Regulation Of Centriole-centriole Cohesion Positive Regulation Of Determination Of Dorsal Identity Lung Induction Embryonic Skeletal Limb Joint Morphogenesis Canonical Wnt Signaling Pathway Involved In Regulation Of Cell Proliferation Central Nervous System Vasculogenesis Trachea Formation Cellular Response To Indole-3-methanol Regulation Of Cell Morphogenesis Regulation Of Cytoskeleton Organization Regulation Of Centromeric Sister Chromatid Cohesion Renal Vesicle Formation Negative Regulation Of Protein Sumoylation Positive Regulation Of Branching Involved In Lung Morphogenesis Exit From Mitosis Regulation Of Mitotic Cell Cycle, Embryonic Positive Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway Regulation Of Branching Involved In Lung Morphogenesis Regulation Of Secondary Heart Field Cardioblast Proliferation Mesenchymal To Epithelial Transition Involved In Metanephros Morphogenesis Fungiform Papilla Formation Establishment Of Blood-brain Barrier Behavioral Response To Ethanol Canonical Wnt Signaling Pathway Involved In Negative Regulation Of Apoptotic Process Fungiform Papilla Morphogenesis Metanephric Renal Vesicle Morphogenesis Endothelial Tube Morphogenesis Glial Cell Proliferation Cell Proliferation Renal Vesicle Morphogenesis Sympathetic Ganglion Development Endodermal Cell Fate Commitment Fungiform Papilla Development Regulation Of Sister Chromatid Cohesion Neural Plate Development Positive Regulation Of Endothelial Cell Differentiation
Tagcloud ?		alphae alphat cardiomyocyte cardiomyocytes catenin catenins coactivator contractility cre delete divide dying gained heart hearts injured knockout lose perinatal proof rationale regulators replace shortly transgenes unable yap yes