CTNNA3 and POU6F2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		CTNNA3	POU6F2
Description		catenin alpha 3	POU class 6 homeobox 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytoskeleton Adherens Junction Fascia Adherens Lamellipodium Desmosome Anchoring Junction	Chromatin Nucleus
	Molecular Function	Protein Binding Beta-catenin Binding Cadherin Binding Actin Filament Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding
	Biological Process	Cell Adhesion Cell Migration Bundle Of His Cell-Purkinje Myocyte Adhesion Involved In Cell Communication Regulation Of Heart Rate By Cardiac Conduction Cell-cell Adhesion Regulation Of Ventricular Cardiac Muscle Cell Action Potential	Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Central Nervous System Development Visual Perception
Pathways
Drugs
Diseases
GWAS		Adventurousness ( 30643258) Adverse response to drug ( 30420678) Asthma (toluene diisocyanate-induced) ( 19187332) Bronchopulmonary dysplasia ( 23897914) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Dental caries ( 23064961) Diffusing capacity of carbon monoxide ( 30694715) Docetaxel-induced peripheral neuropathy in metastatic castrate-resistant prostate cancer ( 27143689) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Epstein-Barr virus copy number in lymphoblastoid cell lines ( 28654678) Essential tremor ( 27797806) General risk tolerance (MTAG) ( 30643258) Household income (MTAG) ( 31844048) Lung function (FVC) ( 24023788) Metabolite levels ( 23823483) Metabolite levels (Pyroglutamine) ( 23934736) Mitochondrial DNA copy number ( 30704525) Nickel levels ( 26025379) Nicotine dependence ( 17158188) Night sleep phenotypes ( 27126917) Obesity-related traits ( 23251661) Optic disc area ( 28073927) Psoriatic arthritis ( 26626624) Pulse pressure ( 27841878) Rheumatic heart disease ( 34106200) Schizophrenia (cytomegalovirus infection interaction) ( 23358160) Subcutaneous adipose tissue ( 29178545) Systemic lupus erythematosus ( 28714469) Systolic blood pressure ( 27841878)	Adult body size ( 32376654) Attention deficit hyperactivity disorder (inattention symptoms) ( 32595297) Caffeine consumption from tea ( 33287642) Feeling hurt ( 29500382) Glaucoma (multi-trait analysis) ( 31959993) Glaucoma (primary open-angle) ( 33627673) Hand grip strength ( 29691431) Intraocular pressure ( 29785010 30054594 31959993) Motion sickness ( 25628336) Refractive error ( 32231278) Tea consumption ( 31046077)
Interacting Genes		67 interacting genes: AKAP9 ATP23 BLOC1S2 C17orf50 CCDC183 CCDC33 CDSN CENPS-CORT CKMT1A CKMT1B CMC2 COG4 CRX CTNNB1 DISC1 ECSIT EID2B EPS8 FAM110A FAM161A FAM161B FAM9A FBXO28 FERD3L GINS3 GNB1 HDX HOMEZ JUP KATNAL1 LASP1 MARCHF7 MBD3L1 MSRA MYOG NAB2 NDUFB7 OIP5 ORC2 PAX6 PLAGL2 PNMA1 PNMA5 POU6F2 PPARA PRR5 REL RIPPLY1 RPS6KA5 SERTAD2 SPATS1 STMN2 TASOR2 TLX3 TNNI1 TNNI2 TRIM54 TXNRD3 USHBP1 VIP ZG16 ZNF19 ZNF426 ZNF474 ZNF552 ZNF620 ZNF662	143 interacting genes: ACTN3 AIRIM ANKRD10 ARHGEF6 ASB13 BANP BFSP2 BHLHE40 C5 CCHCR1 CCNC CCNK CDC23 CDC37 CDKN2C CHAF1A CIB3 CINP CSNK2A1 CSTF2 CTNNA3 DDX6 DTNB DYDC1 EBF1 EIF3F EIF4EBP1 EPHB6 FHL2 FNDC3B FOSB GCM2 GLIS2 GMEB2 GOLGA6L9 HGS HIVEP1 HNF1B HOXC5 HOXC8 HSPA4 IGFN1 IMPDH2 IQUB IRX4 ISX KDF1 KIF5B KLHL11 KPNA5 KPNA6 KRTAP8-1 L3MBTL2 LARP4 LMNB2 LMO3 LNX1 LONRF1 MAGEA12 MAPK9 MEIS2 MIEN1 MLLT10 MORF4L2 MSRB3 MSX2 MYL7 MYO15B NEUROG3 NFYC NKX3-2 NME7 NUP62CL OAZ3 OIP5 OPLAH OPTN PADI4 PARVG PDE6H PIBF1 PKN1 PM20D2 POLR3C POU2F1 PPIL1 PPIP5K2 PROP1 PRR20A PRR20B PRR20C PRR20D PRR20E QRICH1 RAD23B RBM39 RBPMS RELA SIX1 SMAD5 SMYD1 SORL1 SOX10 SSUH2 STAC STRA8 TBX6 TCEA2 TENT5B THADA THAP1 TLX2 TLX3 TNPO2 TNXB TP53BP1 TRIM73 TRIML2 TSC1 TSEN15 TTC19 TTC23 UBAC1 UFSP1 VAX2 VENTX VEZF1 VPS9D1 XPOT ZBTB24 ZBTB4 ZFHX2 ZFHX3 ZFP1 ZFP91 ZIM2 ZMYND12 ZNF148 ZNF319 ZNF34 ZNF384 ZNF410 ZNF574
Entrez ID		29119	11281
HPRD ID		09639	10162
Ensembl ID		ENSG00000183230	ENSG00000106536
Uniprot IDs		A8K141 Q8WW10 Q9UI47	A0A6E1XZL4 P78424
PDB IDs
Enriched GO Terms of Interacting Partners?		Protein Binding Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Catenin-TCF7L2 Complex Regulation Of RNA Metabolic Process Phosphocreatine Biosynthetic Process Creatine Kinase Activity DNA-binding Transcription Activator Activity Regulation Of Transcription By RNA Polymerase II Cellular Response To Indole-3-methanol Response To Indole-3-methanol Positive Regulation Of Neuroblast Proliferation	Regulation Of Transcription By RNA Polymerase II RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Nucleus Sequence-specific Double-stranded DNA Binding Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Gene Expression Protein Binding Chromatin Regulation Of Primary Metabolic Process Regulation Of Macromolecule Biosynthetic Process DNA-binding Transcription Factor Activity Regulation Of Macromolecule Metabolic Process DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific Regulation Of Metabolic Process Positive Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Nucleobase-containing Compound Metabolic Process DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Pattern Specification Process Negative Regulation Of DNA-templated Transcription Sequence-specific DNA Binding Negative Regulation Of RNA Biosynthetic Process Positive Regulation Of RNA Metabolic Process Negative Regulation Of RNA Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Zinc Ion Binding Transcription Cis-regulatory Region Binding Positive Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of Macromolecule Metabolic Process Positive Regulation Of Biosynthetic Process Negative Regulation Of Macromolecule Biosynthetic Process Nucleoplasm Negative Regulation Of Metabolic Process Negative Regulation Of Biosynthetic Process Regulation Of Branch Elongation Involved In Ureteric Bud Branching Stem Cell Differentiation Positive Regulation Of Macromolecule Metabolic Process Positive Regulation Of Metabolic Process Nuclear Import Signal Receptor Activity Animal Organ Development Activation Of Meiosis Nuclear Localization Sequence Binding DNA-templated Transcription
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