SCG3 and DNM1L

Number of citations of the paper that reports this interaction (PubMedID 18330356)
0

Data Source:
BioGRID (two hybrid)

		SCG3	DNM1L
Description		secretogranin III	dynamin 1 like
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region Endoplasmic Reticulum Lumen Membrane Transport Vesicle Transport Vesicle Membrane Secretory Granule Membrane Cytoplasmic Vesicle Secretory Granule Lumen	Cytoplasm Mitochondrion Mitochondrial Outer Membrane Peroxisome Endoplasmic Reticulum Endoplasmic Reticulum Membrane Golgi Apparatus Cytosol Microtubule Brush Border Clathrin-coated Pit Endomembrane System Membrane Synaptic Vesicle Membrane Cytoplasmic Vesicle Protein-containing Complex Synapse Perinuclear Region Of Cytoplasm Mitochondrion-derived Vesicle
	Molecular Function	RNA Binding Protein Binding	Nucleotide Binding GTPase Activity GTPase Activator Activity Protein Binding GTP Binding Microtubule Binding Lipid Binding Hydrolase Activity GTP-dependent Protein Binding Small GTPase Binding Ubiquitin Protein Ligase Binding Identical Protein Binding Protein Homodimerization Activity
	Biological Process	Protein Localization To Secretory Granule	Mitochondrial Fission Calcium Ion Transport Endocytosis Mitochondrion Organization Endoplasmic Reticulum Organization Regulation Of Gene Expression Regulation Of Mitochondrion Organization Programmed Cell Death Peroxisome Fission Mitochondrial Fragmentation Involved In Apoptotic Process Intracellular Distribution Of Mitochondria Rhythmic Process Positive Regulation Of Protein Secretion Protein Complex Oligomerization Heart Contraction Protein Localization To Mitochondrion Positive Regulation Of Neutrophil Chemotaxis Positive Regulation Of Mitochondrial Fission Mitochondrial Membrane Fission Mitocytosis Regulation Of Peroxisome Organization Regulation Of Mitophagy Positive Regulation Of Secretion By Cell Regulation Of ATP Metabolic Process
Pathways		Platelet degranulation Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Post-translational protein phosphorylation	Apoptotic execution phase
Drugs
Diseases
GWAS		Asthma ( 20159242) Blood protein levels ( 30072576) Intelligence (MTAG) ( 29326435) Mean reticulocyte volume ( 32888494)	Mean platelet volume ( 32888494) Platelet count ( 32888494) Platelet distribution width ( 32888494)
Interacting Genes		5 interacting genes: CHGA DNM1L NCAM2 NRIP1 SDCBP	23 interacting genes: CAP2 FILNC1 FIS1 FZR1 GSK3B MAGEA1 MAGEA3 MAP3K10 MFF MIEF1 MIEF2 MUL1 PINK1 PRKN RRM2 SCG3 SENP3 SH3GL1 SIRT3 SUMO2 USP16 VIM ZBTB24
Entrez ID		29106	10059
HPRD ID		11538	04833
Ensembl ID		ENSG00000104112	ENSG00000087470
Uniprot IDs		Q8WXD2	B4DYR6 O00429
PDB IDs			3W6N 3W6O 3W6P 4BEJ 4H1U 4H1V 5WP9 8T1H
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Relaxation Of Cardiac Muscle Positive Regulation Of Dense Core Granule Biogenesis Mast Cell Chemotaxis Regulation Of Secretion Chromaffin Granule Regulation Of Secretion By Cell Protein Localization To Secretory Granule Interleukin-5 Receptor Binding Interleukin-5 Receptor Complex Positive Regulation Of Extracellular Exosome Assembly Syndecan Binding Ovarian Follicle Rupture Mitochondrion-derived Vesicle Mitochondrial Membrane Fission Regulation Of Peroxisome Organization Mitocytosis Positive Regulation Of Phospholipase C-activating G Protein-coupled Receptor Signaling Pathway Regulation Of Relaxation Of Cardiac Muscle Mast Cell Migration Regulation Of Extracellular Exosome Assembly Response To Gonadotropin-releasing Hormone Intracellular Distribution Of Mitochondria	Positive Regulation Of Mitochondrial Fission Regulation Of Mitochondrial Fission Regulation Of Mitochondrion Organization Mitochondrial Fission Mitochondrion Organization Mitochondrial Outer Membrane Peroxisome Positive Regulation Of Organelle Organization Positive Regulation Of Type 2 Mitophagy Regulation Of Mitochondrial Fusion Cellular Response To Toxic Substance Positive Regulation Of Post-translational Protein Modification Positive Regulation Of Establishment Of Protein Localization Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Mitophagy Mitochondrion To Lysosome Vesicle-mediated Transport Cellular Response To Hydrogen Sulfide Regulation Of Proteasomal Protein Catabolic Process Positive Regulation Of Protein Metabolic Process Positive Regulation Of Autophagy Of Mitochondrion Positive Regulation Of Protein Modification Process Regulation Of Proteolysis Regulation Of Anatomical Structure Morphogenesis Positive Regulation Of Mitochondrial Fusion Response To Hydrogen Sulfide Positive Regulation Of Ubiquitin-dependent Protein Catabolic Process Regulation Of Organelle Organization Positive Regulation Of Protein Ubiquitination Positive Regulation Of Proteasomal Protein Catabolic Process Regulation Of Post-translational Protein Modification Negative Regulation Of Mitochondrial Fission Regulation Of Synaptic Vesicle Transport Negative Regulation Of Reactive Oxygen Species Metabolic Process Protein Modification Process Lewy Body Positive Regulation Of Proteolysis Involved In Protein Catabolic Process Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Regulation Of Mitophagy Negative Regulation Of Mitochondrial Fusion Ubiquitin Protein Ligase Binding Regulation Of Autophagy Of Mitochondrion Regulation Of Establishment Of Protein Localization Positive Regulation Of Cellular Component Organization Regulation Of Catalytic Activity Positive Regulation Of Catabolic Process Mitochondrial Fragmentation Involved In Apoptotic Process Regulation Of Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Autophagy Post-translational Protein Modification Regulation Of Protein Metabolic Process
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