SLC25A4 and PPIF

Number of citations of the paper that reports this interaction (PubMedID 9874241)
0

Data Source:
HPRD (in vitro)

		SLC25A4	PPIF
Description		solute carrier family 25 member 4	peptidylprolyl isomerase F
Image		No pdb structure
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Inner Membrane Mitochondrial Permeability Transition Pore Complex Plasma Membrane Membrane Mitochondrial Membrane	Cytoplasm Mitochondrion Mitochondrial Permeability Transition Pore Complex Mitochondrial Matrix Membrane
	Molecular Function	ATP:ADP Antiporter Activity Protein Binding Proton Transmembrane Transporter Activity Adenine Transmembrane Transporter Activity Antiporter Activity Oxidative Phosphorylation Uncoupler Activity	Peptidyl-prolyl Cis-trans Isomerase Activity Protein Binding Cyclosporin A Binding Isomerase Activity
	Biological Process	Generation Of Precursor Metabolites And Energy Apoptotic Mitochondrial Changes Adenine Transport ADP Transport Regulation Of Mitochondrial Membrane Permeability Transmembrane Transport Negative Regulation Of Necroptotic Process Mitochondrial ADP Transmembrane Transport Negative Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Positive Regulation Of Mitophagy Proton Transmembrane Transport Mitochondrial ATP Transmembrane Transport Adaptive Thermogenesis	Response To Ischemia Protein Folding Apoptotic Process Response To Oxidative Stress Mitochondrion Organization Apoptotic Mitochondrial Changes Regulation Of Proton-transporting ATPase Activity, Rotational Mechanism Programmed Cell Death Negative Regulation Of Apoptotic Process Regulation Of Mitochondrial Membrane Permeability Mitochondrial Depolarization Muscle Structure Development Necroptotic Process Cellular Response To Hydrogen Peroxide Cellular Response To Arsenic-containing Substance Cellular Response To Calcium Ion Negative Regulation Of Release Of Cytochrome C From Mitochondria Negative Regulation Of Oxidative Phosphorylation Skeletal Muscle Fiber Differentiation Regulation Of Mitochondrial Membrane Permeability Involved In Programmed Necrotic Cell Death Mitochondrial Outer Membrane Permeabilization Involved In Programmed Cell Death Negative Regulation Of Intrinsic Apoptotic Signaling Pathway
Pathways		Mitochondrial protein import Mitochondrial protein import Mitochondrial Uncoupling Vpr-mediated induction of apoptosis by mitochondrial outer membrane permeabilization Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane
Drugs		ATP Clodronic acid Etidronic acid [3-(Dodecanoylamino)Propyl](Hydroxy)Dimethylammonium Carboxyatractyloside Tetrastearoyl cardiolipin Di-Stearoyl-3-Sn-Phosphatidylcholine	Cyclosporine Proline Triglyme Coumarin 120
Diseases
GWAS			Appendicular lean mass ( 33097823) Blood protein levels ( 30072576) Height ( 20881960 31562340) High light scatter reticulocyte count ( 27863252 32888494) High light scatter reticulocyte percentage of red cells ( 27863252 32888494) Hip circumference adjusted for BMI ( 34021172) Immature fraction of reticulocytes ( 32888494) Liver enzyme levels (alkaline phosphatase) ( 33972514) Mean platelet volume ( 32888494) Metabolite levels ( 23823483) Triglyceride levels ( 32203549)
Interacting Genes		7 interacting genes: AR BAX NFKBIA NR3C1 PPID PPIF PRKCE	19 interacting genes: ABI2 AGTRAP ARFIP2 BANP CIDEB CMTM5 FAM25A FAM25C FAM25G FKBP7 MAGEA11 MUC1 PRB3 SERPINB5 SLC25A4 SYP SYPL1 VDAC1 YIF1A
Entrez ID		291	10105
HPRD ID		00058	06839
Ensembl ID		ENSG00000151729	ENSG00000108179
Uniprot IDs		A0A0S2Z3H3 P12235	P30405
PDB IDs			2BIT 2BIU 2Z6W 3QYU 3R49 3R4G 3R54 3R56 3R57 3R59 3RCF 3RCG 3RCI 3RCK 3RCL 3RD9 3RDA 3RDB 3RDC 4J58 4J59 4J5A 4J5B 4J5C 4J5D 4J5E 4O8H 4O8I 4XNC 4ZSC 4ZSD 5A0E 5CBT 5CBU 5CBV 5CBW 5CCN 5CCQ 5CCR 5CCS 6R8L 6R8O 6R8W 6R9S 6R9U 6R9X 6RA1 6Y3E 6YBM 7OGI 7PMT 7R2H 7R2I 7R2J 7R2L 7TGS 7TGT 7TGU 7TGV 7TH1 7TH6 7TH7 7THC 7THD 7THF 7ZDN 8EJX 8UC4 8UC5
Enriched GO Terms of Interacting Partners?		Regulation Of Mitochondrial Membrane Permeability Involved In Programmed Necrotic Cell Death Mitochondrial Permeability Transition Pore Complex Estrogen Response Element Binding Apoptotic Process Programmed Cell Death Cell Death Cyclosporin A Binding Mitochondrial Outer Membrane Permeabilization Involved In Programmed Cell Death Regulation Of Cellular Localization Steroid Binding Positive Regulation Of Mitochondrial Membrane Permeability Regulation Of Programmed Cell Death Regulation Of Apoptotic Process Negative Regulation Of Apoptotic Signaling Pathway Response To Ketone Intracellular Receptor Signaling Pathway Positive Regulation Of Membrane Permeability Peptidyl-prolyl Cis-trans Isomerase Activity Immune Response-activating Cell Surface Receptor Signaling Pathway Lipopolysaccharide-mediated Signaling Pathway Negative Regulation Of Metabolic Process Regulation Of Transport Regulation Of Monoatomic Cation Transmembrane Transport Hsp90 Protein Binding Toll-like Receptor 4 Signaling Pathway Regulation Of Release Of Cytochrome C From Mitochondria Response To Lipid Immune Response-regulating Cell Surface Receptor Signaling Pathway Cell Surface Toll-like Receptor Signaling Pathway Regulation Of Monoatomic Ion Transmembrane Transport Hsp70 Protein Binding Nuclear Receptor Activity B Cell Receptor Signaling Pathway Cellular Response To Oxygen-containing Compound Cell Surface Pattern Recognition Receptor Signaling Pathway Intracellular Signal Transduction Positive Regulation Of MiRNA Transcription Regulation Of Mitochondrial Membrane Permeability Regulation Of Protein Localization Lipid Binding Cellular Response To Hormone Stimulus Positive Regulation Of MiRNA Metabolic Process Immune Response-activating Signaling Pathway Negative Regulation Of Transcription By RNA Polymerase II Apoptotic Mitochondrial Changes Enzyme Binding Prostate Induction Regulation Of Apoptotic Signaling Pathway Regulation Of MiRNA Transcription Regulation Of Intracellular Signal Transduction	Mitochondrial Permeability Transition Pore Complex
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