PPIF and SLC25A4

Number of citations of the paper that reports this interaction (PMID 9874241)
66

Data Source:
HPRD (in vitro)

		PPIF	SLC25A4
Gene Name		peptidylprolyl isomerase F	solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Mitochondrial Proton-transporting ATP Synthase Complex Mitochondrial Matrix Membrane	Nucleus Mitochondrion Mitochondrial Inner Membrane Integral Component Of Plasma Membrane
	Molecular Function	Peptidyl-prolyl Cis-trans Isomerase Activity Protein Binding Cyclosporin A Binding	Protein Binding Adenine Transmembrane Transporter Activity
	Biological Process	Protein Peptidyl-prolyl Isomerization Response To Ischemia Protein Folding Apoptotic Mitochondrial Changes Regulation Of Proton-transporting ATPase Activity, Rotational Mechanism Regulation Of Necrotic Cell Death Negative Regulation Of ATPase Activity Negative Regulation Of Apoptotic Process Regulation Of Mitochondrial Membrane Permeability Necroptotic Process Cellular Response To Hydrogen Peroxide Cellular Response To Arsenic-containing Substance Cellular Response To Calcium Ion Positive Regulation Of Release Of Cytochrome C From Mitochondria Negative Regulation Of Release Of Cytochrome C From Mitochondria Negative Regulation Of Oxidative Phosphorylation Regulation Of Mitochondrial Membrane Permeability Involved In Programmed Necrotic Cell Death Negative Regulation Of Oxidative Phosphorylation Uncoupler Activity Negative Regulation Of Intrinsic Apoptotic Signaling Pathway	Mitochondrial Genome Maintenance Generation Of Precursor Metabolites And Energy Energy Reserve Metabolic Process Transport Apoptotic Mitochondrial Changes Adenine Transport Viral Process Small Molecule Metabolic Process Regulation Of Insulin Secretion Transmembrane Transport Negative Regulation Of Necroptotic Process
Pathways			Integration of energy metabolism Vpr-mediated induction of apoptosis by mitochondrial outer membrane permeabilization HIV Infection Regulation of insulin secretion Host Interactions of HIV factors Mitochondrial protein import Interactions of Vpr with host cellular proteins
Drugs		L-Proline 1-Methoxy-2-[2-(2-Methoxy-Ethoxy]-Ethane 7-AMINO-4-METHYL-CHROMEN-2-ONE	Adenosine triphosphate Clodronate [3-(Dodecanoylamino)Propyl](Hydroxy)Dimethylammonium Carboxyatractyloside Cardiolipin Di-Stearoyl-3-Sn-Phosphatidylcholine
Diseases
GWAS		Height ( 20881960)
Protein-Protein Interactions		5 interactors: ABI2 BANP CMTM5 SLC25A4 VDAC1	7 interactors: AR BAX NFKBIA NR3C1 PPID PPIF PRKCE
Entrez ID		10105	291
HPRD ID		06839	00058
Ensembl ID		ENSG00000108179	ENSG00000151729
Uniprot IDs		P30405 Q2YDB7	P12235
PDB IDs		2BIT 2BIU 2Z6W 3QYU 3R49 3R4G 3R54 3R56 3R57 3R59 3RCF 3RCG 3RCI 3RCK 3RCL 3RD9 3RDA 3RDB 3RDC
Enriched GO Terms of Interacting Partners?		Adenine Transport Purine Nucleobase Transport Learning Or Memory Nucleobase Transport Cognition Positive Regulation Of Arp2/3 Complex-mediated Actin Nucleation Positive Regulation Of Actin Nucleation	Regulation Of Mitochondrial Membrane Permeability Involved In Programmed Necrotic Cell Death Regulation Of Apoptotic Process Regulation Of Cell Death Apoptotic Process Programmed Cell Death Regulation Of Cellular Localization Cellular Response To Lipid Cell Death Death Negative Regulation Of Signal Transduction Negative Regulation Of Signaling Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Positive Regulation Of Cell Death Regulation Of Signal Transduction Intracellular Receptor Signaling Pathway Regulation Of Nitrogen Compound Metabolic Process Regulation Of Establishment Of Protein Localization Positive Regulation Of Release Of Cytochrome C From Mitochondria Positive Regulation Of Transport Regulation Of Signaling Regulation Of Protein Localization Negative Regulation Of Apoptotic Signaling Pathway Regulation Of Mitochondrial Membrane Permeability Regulation Of Membrane Permeability Response To Lipid Lipopolysaccharide-mediated Signaling Pathway Cellular Response To Organic Substance Immune Response-activating Cell Surface Receptor Signaling Pathway Response To Organic Cyclic Compound Negative Regulation Of Transporter Activity Negative Regulation Of Apoptotic Process Programmed Necrotic Cell Death Negative Regulation Of Programmed Cell Death Necrotic Cell Death Negative Regulation Of Cell Death Negative Regulation Of Transmembrane Transport Positive Regulation Of Mitochondrion Organization Immune Response-regulating Cell Surface Receptor Signaling Pathway Positive Regulation Of Neuron Apoptotic Process Cellular Response To UV Cellular Response To Stimulus Mitochondrial Membrane Organization Response To Abiotic Stimulus Negative Regulation Of Transport Intracellular Steroid Hormone Receptor Signaling Pathway MyD88-independent Toll-like Receptor Signaling Pathway Positive Regulation Of Organelle Organization Apoptotic Mitochondrial Changes Positive Regulation Of Neuron Death
Tagcloud ?		accelerated autocrine bioenergetics called chemokine chemotaxis cxcl12 cxcr4 cyclophilin cypd decisions directs enhances entry extensive fate isomerase mediator mitochondria modulation motility nuclei paracrine peptidyl pleiotropic prolyl signature stimulates traits	aberrantly af anr atrial autonomic bioinformatics canine copyright dysregulated fgf19 fgf3 fgf4 fibrillation filtering inducibility lentiviruses lncrnas nearby neurogenesis orchestrators pads pipelines prolong reserved rights shorten tcons transcriptomes twofold
Tagcloud (Difference) ?		accelerated autocrine bioenergetics called chemokine chemotaxis cxcl12 cxcr4 cyclophilin cypd decisions directs enhances entry extensive fate isomerase mediator mitochondria modulation motility nuclei paracrine peptidyl pleiotropic prolyl signature stimulates traits	aberrantly af anr atrial autonomic bioinformatics canine copyright dysregulated fgf19 fgf3 fgf4 fibrillation filtering inducibility lentiviruses lncrnas nearby neurogenesis orchestrators pads pipelines prolong reserved rights shorten tcons transcriptomes twofold
Tagcloud (Intersection) ?