PPIF and VDAC1

Number of citations of the paper that reports this interaction (PMID 9874241)
66

Data Source:
HPRD (in vitro)

		PPIF	VDAC1
Gene Name		peptidylprolyl isomerase F	voltage-dependent anion channel 1
Image
Gene Ontology Annotations	Cellular Component	Mitochondrial Proton-transporting ATP Synthase Complex Mitochondrial Matrix Membrane	Nucleus Mitochondrion Mitochondrial Outer Membrane Mitochondrial Inner Membrane Plasma Membrane Membrane Mitochondrial Nucleoid Pore Complex Extracellular Vesicular Exosome
	Molecular Function	Peptidyl-prolyl Cis-trans Isomerase Activity Protein Binding Cyclosporin A Binding	Protein Binding Voltage-gated Anion Channel Activity Porin Activity Protein Kinase Binding
	Biological Process	Protein Peptidyl-prolyl Isomerization Response To Ischemia Protein Folding Apoptotic Mitochondrial Changes Regulation Of Proton-transporting ATPase Activity, Rotational Mechanism Regulation Of Necrotic Cell Death Negative Regulation Of ATPase Activity Negative Regulation Of Apoptotic Process Regulation Of Mitochondrial Membrane Permeability Necroptotic Process Cellular Response To Hydrogen Peroxide Cellular Response To Arsenic-containing Substance Cellular Response To Calcium Ion Positive Regulation Of Release Of Cytochrome C From Mitochondria Negative Regulation Of Release Of Cytochrome C From Mitochondria Negative Regulation Of Oxidative Phosphorylation Regulation Of Mitochondrial Membrane Permeability Involved In Programmed Necrotic Cell Death Negative Regulation Of Oxidative Phosphorylation Uncoupler Activity Negative Regulation Of Intrinsic Apoptotic Signaling Pathway	Behavioral Fear Response Anion Transport Apoptotic Process Neuron-neuron Synaptic Transmission Learning Viral Process Epithelial Cell Differentiation Regulation Of Anion Transport Transmembrane Transport
Pathways			Mitochondrial protein import
Drugs		L-Proline 1-Methoxy-2-[2-(2-Methoxy-Ethoxy]-Ethane 7-AMINO-4-METHYL-CHROMEN-2-ONE
Diseases
GWAS		Height ( 20881960)
Protein-Protein Interactions		5 interactors: ABI2 BANP CMTM5 SLC25A4 VDAC1	20 interactors: ADRB2 BAK1 BAX BCL2L1 BCL2L11 CKMT1A CKMT1B CSNK2B DYNLT1 DYNLT3 GSN HK1 KLHL40 MCL1 PPIF PRKCE RAF1 SUMO4 TOMM20 TUBA4A
Entrez ID		10105	7416
HPRD ID		06839	05137
Ensembl ID		ENSG00000108179	ENSG00000213585
Uniprot IDs		P30405 Q2YDB7	B3KTS5 P21796
PDB IDs		2BIT 2BIU 2Z6W 3QYU 3R49 3R4G 3R54 3R56 3R57 3R59 3RCF 3RCG 3RCI 3RCK 3RCL 3RD9 3RDA 3RDB 3RDC	2JK4 2K4T
Enriched GO Terms of Interacting Partners?		Adenine Transport Purine Nucleobase Transport Learning Or Memory Nucleobase Transport Cognition Positive Regulation Of Arp2/3 Complex-mediated Actin Nucleation Positive Regulation Of Actin Nucleation	Apoptotic Mitochondrial Changes Regulation Of Mitochondrial Membrane Permeability Regulation Of Membrane Permeability Extrinsic Apoptotic Signaling Pathway Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Mitochondrial Membrane Organization Mitochondrial Transport Positive Regulation Of Release Of Cytochrome C From Mitochondria Thymocyte Apoptotic Process B Cell Apoptotic Process Post-embryonic Organ Morphogenesis Positive Regulation Of Apoptotic Signaling Pathway Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Regulation Of Mitochondrion Organization Mitochondrion Organization Positive Regulation Of Signal Transduction Apoptotic Process Programmed Cell Death Cell Death Death Positive Regulation Of Mitochondrion Organization Regulation Of Intrinsic Apoptotic Signaling Pathway Positive Regulation Of Intrinsic Apoptotic Signaling Pathway T Cell Apoptotic Process Apoptotic Signaling Pathway Transport Regulation Of Organelle Organization Intrinsic Apoptotic Signaling Pathway Positive Regulation Of Organelle Organization B Cell Negative Selection Apoptotic Process Involved In Morphogenesis Organelle Organization Apoptotic Process Involved In Development Establishment Of Localization In Cell Intracellular Transport Release Of Cytochrome C From Mitochondria Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Negative Regulation Of Apoptotic Signaling Pathway Regulation Of Mitochondrial Membrane Permeability Involved In Programmed Necrotic Cell Death Apoptotic Process Involved In Embryonic Digit Morphogenesis Post-embryonic Camera-type Eye Morphogenesis Positive Regulation Of Intracellular Signal Transduction Regulation Of Mitochondrial Membrane Potential Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Regulation Of Signal Transduction B Cell Homeostasis Establishment Or Maintenance Of Transmembrane Electrochemical Gradient Developmental Programmed Cell Death Regulation Of Intracellular Signal Transduction Positive Regulation Of Apoptotic Process
Tagcloud ?		accelerated autocrine bioenergetics called chemokine chemotaxis cxcl12 cxcr4 cyclophilin cypd decisions directs enhances entry extensive fate isomerase mediator mitochondria modulation motility nuclei paracrine peptidyl pleiotropic prolyl signature stimulates traits	000xg calreticulin cd81 centrifugation cleared contaminating devoid dulbecco eagle exosomal exosome exosomes fill fl3 hek293 impacted microsomes nanoparticle nta overnight pelleted phenol purity sedimentation speeds syntenin tsg101 ultracentrifugation vesicle
Tagcloud (Difference) ?		accelerated autocrine bioenergetics called chemokine chemotaxis cxcl12 cxcr4 cyclophilin cypd decisions directs enhances entry extensive fate isomerase mediator mitochondria modulation motility nuclei paracrine peptidyl pleiotropic prolyl signature stimulates traits	000xg calreticulin cd81 centrifugation cleared contaminating devoid dulbecco eagle exosomal exosome exosomes fill fl3 hek293 impacted microsomes nanoparticle nta overnight pelleted phenol purity sedimentation speeds syntenin tsg101 ultracentrifugation vesicle
Tagcloud (Intersection) ?